Regulation of mitochondrial pyruvate dehydrogenase activity by tau protein kinase I/glycogen synthase kinase 3beta in brain. - Wikidata - wikimedia - TriplyDB

Regulation of mitochondrial pyruvate dehydrogenase activity by tau protein kinase I/glycogen synthase kinase 3beta in brain.

Regulation of mitochondrial pyruvate dehydrogenase activity by tau protein kinase I/glycogen synthase kinase 3beta in brain.

http://www.wikidata.org/entity/Q37672243

about

Recent developments of protein kinase inhibitors as potential AD therapeutics Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau Regulation of mitochondrial functions by protein phosphorylation and dephosphorylation Glycogen Synthase Kinase-3 (GSK-3)-Targeted Therapy and Imaging Neuronal response in Alzheimer's and Parkinson's disease: the effect of toxic proteins on intracellular pathways Molecular and biochemical trajectories from diabetes to Alzheimer's disease: A critical appraisal Structural insights and biological effects of glycogen synthase kinase 3-specific inhibitor AR-A014418 Mood stabilizers, glycogen synthase kinase-3beta and cell survival GSK3beta in ethanol neurotoxicity The role of GSK3beta in the development of the central nervous system Light and electron microscopy study of glycogen synthase kinase-3beta in the mouse brain GSK-3: Functional Insights from Cell Biology and Animal Models.Abnormalities in brain structure and behavior in GSK-3alpha mutant mice A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation.Improvement by nefiracetam of beta-amyloid-(1-42)-induced learning and memory impairments in rats.Regulation of glycogen synthase kinase 3beta and downstream Wnt signaling by axin Stable isotope-resolved metabolomic analysis of lithium effects on glial-neuronal metabolism and interactions MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease Glycogen synthase kinase-3beta (GSK3beta) binds to and promotes the actions of p53.Regulation of tau phosphorylation and protection against beta-amyloid-induced neurodegeneration by lithium. Possible implications for Alzheimer's disease.What Are the bona fide GSK3 Substrates?Bioenergetics breakdown in Alzheimer's disease: targets for new therapies Large-scale in silico modeling of metabolic interactions between cell types in the human brain.Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta Inhibition of GSK-3beta as a target for cardioprotection: the importance of timing, location, duration and degree of inhibition.A model for dynamic regulation of choline acetyltransferase by phosphorylation.GSK3β inhibition protects the immature brain from hypoxic-ischaemic insult via reduced STAT3 signalling.D-beta-hydroxybutyrate protects neurons in models of Alzheimer's and Parkinson's disease The GSK3 hypothesis of Alzheimer's disease Regulation and localization of tyrosine216 phosphorylation of glycogen synthase kinase-3beta in cellular and animal models of neuronal degeneration.The marine natural-derived inhibitors of glycogen synthase kinase-3beta phenylmethylene hydantoins: In vitro and in vivo activities and pharmacophore modeling.Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration.Protein kinase networks regulating glucocorticoid-induced apoptosis of hematopoietic cancer cells: fundamental aspects and practical considerations.Targeting Glycogen Synthase Kinase-3β for Therapeutic Benefit against Oxidative Stress in Alzheimer's Disease: Involvement of the Nrf2-ARE Pathway.The pyruvate dehydrogenase complex as a therapeutic target for age-related diseases.GSK-3 and mitochondria in cancer cells.Regulation of pyruvate metabolism in metabolic-related diseases.GSK-3β, a pivotal kinase in Alzheimer disease.The mitochondrial permeability transition pore and its adaptive responses in tumor cells.

P2860

Q21129481-789E303B-8404-4C2A-BE3A-B4A50DF25441 Q24320124-D5359CCB-A9D1-4134-A5ED-775B0B04BEFC Q26752880-4665A566-57B1-4781-85D1-F6E818044A89 Q26768475-8EB575C7-1D82-47BD-AF54-4AB119B16513 Q26779424-31596831-8316-4878-B4EC-7D7A3FE38112 Q26783344-C41E2688-A8C0-423C-A771-C7806F93AB28 Q27641873-982E2DE9-D55F-4677-BB69-E0186422C9D5 Q28216404-E31F7E2B-1CAF-4490-82BF-F9C952EA3B86 Q28387181-47E0CDCE-A30B-459A-A583-36AE79EF2971 Q28387853-8881284B-1DDF-4ED7-A412-FF1916F3DDB7 Q28472669-903E4863-CFD8-4170-B680-48FCB9447D56 Q30472813-42140727-03FC-41E3-9CFC-4172F586E60B Q30485018-BD49DF8D-4E20-4359-9C24-0076F1F38802 Q30538459-3A1499D0-01AB-42D4-981A-75656BDA5D59 Q31034955-BA47084B-857F-4655-83B8-8AFC66C46233 Q33853596-D935F217-8841-459A-8AA4-F48BE0F5C847 Q33959834-77B9C51D-B051-4C1A-B5D7-D0E6C24C2D8A Q33989596-E4D34E8C-A78E-4DFC-95F5-FC3CD81B881C Q34324544-DFE6054D-D315-45EA-A561-10C07AE4BD2F Q34338748-DA20A165-B134-4468-ACB7-A19B5D406001 Q34785749-EA64CFBE-4F26-4A3E-B520-BA198DBA3E44 Q35001234-A6B59B16-3CF8-46F6-ABC1-ABC575A15EF0 Q35098445-884AE57A-EB50-481C-BFCD-1F8D925451BF Q35117087-3C411F48-CF1B-4802-842D-F63A927E542A Q35142950-B03AC4BF-0DD0-4D7F-A1F4-70C3FB050228 Q36158687-8C519011-D7FC-40FA-BF6E-0C8B7BB231F5 Q36245818-EA5C66FF-876D-450E-829D-9D3AC8CAAC46 Q36378223-CF9FFC60-CA4A-4158-9223-84ACD014D86A Q36976707-B6F3F3E7-D50F-4F7B-842A-2A37812340A8 Q37035378-A55A259E-9513-466B-A5CF-5C5666A21CDB Q37273048-00986D71-5E65-481C-BE85-C6B5BAB574DB Q37345648-C21B2DE3-6017-4DBC-9DC1-F2C82514C8C2 Q37710447-6569EF97-C61E-43D2-B4E3-50C48E945DA8 Q37789771-AC180307-1BA1-4ADC-814C-FBF061E0DB21 Q37883102-9246790E-98C1-4E37-B55E-FC175AE2DA34 Q37982890-7F74339B-C337-4E56-AE42-2FE61C105309 Q38079592-57B4F3BD-BB73-4AF6-B1D1-909AE05ED9C0 Q38161453-AE210E6B-94F1-40FF-94D2-99765F6B51AD Q38218085-6218E778-4E1F-498E-B7B5-6EC8B50AB5F1 Q38278265-7066DBD9-4C74-4DBB-BF6B-EA4427676EAD

P2860

Regulation of mitochondrial pyruvate dehydrogenase activity by tau protein kinase I/glycogen synthase kinase 3beta in brain.

http://www.wikidata.org/entity/Q37672243

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on April 1996

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Regulation of mitochondrial py ...... ynthase kinase 3beta in brain.

@en

Regulation of mitochondrial py ...... ynthase kinase 3beta in brain.

@nl

type

label

Regulation of mitochondrial py ...... ynthase kinase 3beta in brain.

@en

Regulation of mitochondrial py ...... ynthase kinase 3beta in brain.

@nl

prefLabel

Regulation of mitochondrial py ...... ynthase kinase 3beta in brain.

@en

Regulation of mitochondrial py ...... ynthase kinase 3beta in brain.

@nl

P1433

Q37672243-20EE2107-5E62-4327-B214-A156A1A4EDDB

P1476

Q37672243-D2EA7ADB-EAE8-4011-BF9F-F8D39A4D164A

P2093

Q37672243-016C08ED-6361-4668-AB7B-DD828E2076E9

Q37672243-1104E76F-FFC8-4FA5-8947-4A5851C1C409

Q37672243-431BD895-0B51-4116-9192-26429F4F76B1

Q37672243-46FC3F9D-DBC4-4034-B173-EC8F5CB84A96

Q37672243-501DB388-8F48-4E2E-A2B9-4EA1FEDF7FBF

Q37672243-7A6061CB-D2FA-4721-A50D-E868261DE045

Q37672243-87A15EE1-4E93-4AF7-8769-F04C1BE42E0F

Q37672243-A7EBF49E-B6D8-4444-9CC5-721B1B7BA2FA

Q37672243-BD7D1D9E-B54C-4F7B-B4BC-953806BCFD25

Q37672243-E83AA2E8-AC3C-43BF-8CBF-F370EFADC796

P2860

Q37672243-11792C4D-4CEF-4578-BCFA-610E03CC0CFD

Q37672243-11CF27FF-E8AA-4B21-A3A0-691B86F538C4

Q37672243-1593ECF8-2C50-446D-8F77-85CC25805677

Q37672243-1A18F763-D7D8-4C54-AF8F-0439EABAB509

Q37672243-23218771-BEB4-4B2B-8A3F-30F6BFB2FEB2

Q37672243-24457662-D5DE-4988-91CD-A056514F8DC2

Q37672243-3A479373-EAE5-4270-B9E0-4C0ACA42429D

Q37672243-47C635E3-9030-43BD-9679-CB410DD79E67

Q37672243-47CEFBC7-FAC8-4D8D-B7E4-4440730B1258

Q37672243-543BF6ED-3A64-44F5-A890-15484033666C

P304

Q37672243-6ED682CF-B4EB-4936-9C10-B29674BB4BA8

P31

Q37672243-14FB3836-0A1A-4B06-9E91-A7D323925898

P356

Q37672243-4D7EFD89-917C-4D38-AE97-FC71CFAFDEFB

P407

Q37672243-55A3340D-F223-4E1C-8D8F-B482682731B2

P433

Q37672243-8825A14C-AE5A-42EC-81FA-340D82AF25B3

P478

Q37672243-16F87631-632A-4549-8171-BA420A5F83BD

P577

Q37672243-3BCDDB4C-9176-4868-AE95-0ABED6E7EE65

P5875

Q37672243-D3B2DFFA-444C-490E-8C33-A9F371982CFA

P698

Q37672243-89C79388-5A3F-4280-ACCA-4B71CA0FDF0D

P921

Q37672243-5844E9D7-1EFE-4AE2-A3AE-6977B02F5027

P932

Q37672243-65E40A3B-AB00-45D9-9A45-9F2D2A54974C

P356

P1433

Proceedings of the National Academy of Sciences of the United States of America

P1476

Regulation of mitochondrial py ...... ynthase kinase 3beta in brain.

@en

P2093

Hoshi M

http://www.w3.org/2001/XMLSchema#string

Hoshino T

http://www.w3.org/2001/XMLSchema#string

Imahori K

http://www.w3.org/2001/XMLSchema#string

Ishiguro K

http://www.w3.org/2001/XMLSchema#string

Kondo S

http://www.w3.org/2001/XMLSchema#string

Murayama M

http://www.w3.org/2001/XMLSchema#string

Noguchi K

http://www.w3.org/2001/XMLSchema#string

Saitoh Y

http://www.w3.org/2001/XMLSchema#string

Sato M

http://www.w3.org/2001/XMLSchema#string

Takashima A

http://www.w3.org/2001/XMLSchema#string

P2860

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

A novel genetic system to detect protein-protein interactions

Tau protein kinase I is essential for amyloid beta-protein-induced neurotoxicity

Molecular cloning and expression of glycogen synthase kinase-3/factor A

Different localization of tau protein kinase I/glycogen synthase kinase-3 beta from glycogen synthase kinase-3 alpha in cerebellum mitochondria

Primary structure of pyruvate dehydrogenase kinase establishes a new family of eukaryotic protein kinases

Alzheimer's disease: the amyloid cascade hypothesis

Abnormal phosphorylation of the microtubule-associated protein tau (tau) in Alzheimer cytoskeletal pathology

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

P304

2719-2723

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1073/PNAS.93.7.2719

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

93

http://www.w3.org/2001/XMLSchema#string

P577

1996-04-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

14590662

http://www.w3.org/2001/XMLSchema#string

P698

8610107

http://www.w3.org/2001/XMLSchema#string

P921

P932

39697

http://www.w3.org/2001/XMLSchema#string