An enhancer-like element in the adenovirus E2 promoter contains sequences essential for uninduced and E1A-induced transcription.
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E4F and ATF, two transcription factors that recognize the same site, can be distinguished both physically and functionally: a role for E4F in E1A trans activationIsolation and characterization of two novel, closely related ATF cDNA clones from HeLa cellsCREB regulation of cellular cyclic AMP-responsive and adenovirus early promoters.Adenoviral control regions activated by E1A and the cAMP response element bind to the same factor.The 289-amino acid E1A protein of adenovirus binds zinc in a region that is important for trans-activation.Cyclic AMP induction of early adenovirus promoters involves sequences required for E1A trans-activationDNA octamer element can confer E1A trans-activation, and adenovirus infection results in a stimulation of the DNA-binding activity of OTF-1/NFIII factor.Phosphorylation-dependent activation of the adenovirus-inducible E2F transcription factor in a cell-free system.Adenovirus stimulation of transcription by RNA polymerase III: evidence for an E1A-dependent increase in transcription factor IIIC concentration.Simian virus 40 small t antigen trans activates the adenovirus E2A promoter by using mechanisms distinct from those used by adenovirus E1A.Promoter trans-activation of protooncogenes c-fos and c-myc, but not c-Ha-ras, by products of adenovirus early region 1ARole of an adenovirus E2 promoter binding factor in E1A-mediated coordinate gene control.The E4 promoter of adenovirus type 2 contains an E1A dependent cis-acting element.Activation of the mouse DNA polymerase beta gene promoter by adenovirus type 12 E1A proteins.In vivo photocrosslinking reveals that transcription factor binding to the mammalian ATF recognition sequence is required for E1A-induced transactivation in injected Xenopus laevis oocytes.The C-terminal 70 amino acids of the adenovirus E4-ORF6/7 protein are essential and sufficient for E2F complex formationThe embryonal carcinoma stem cell Ela-like activity involves a differentiation-regulated transcription factor.Sequence-specific and general transcriptional activation by the bovine papillomavirus-1 E2 trans-activator require an N-terminal amphipathic helix-containing E2 domain.Transrepression of RNA polymerase II promoters by the simian virus 40 small t antigen.Transcriptional activation of several heterologous promoters by the E6 protein of human papillomavirus type 16.Adenovirus E4-dependent activation of the early E2 promoter is insufficient to promote the early-to-late-phase transitionE1A represses wild-type and F9-selected polyomavirus DNA replication by a mechanism not requiring depression of large tumor antigen transcriptionAn embryonic enhancer determines the temporal activation of a sea urchin late H1 gene.Adenovirus E1A-mediated negative control of genes activated during F9 differentiation.Factors responsible for the higher transcriptional activity of extracts of adenovirus-infected cells fractionate with the TATA box transcription factorSequences upstream of AAUAAA influence poly(A) site selection in a complex transcription unit.Genetic analysis of the adenovirus E4 6/7 trans activator: interaction with E2F and induction of a stable DNA-protein complex are critical for activityThe adenovirus EII early promoter has multiple EIA-sensitive elements, two of which function cooperatively in basal and virus-induced transcriptionThe cellular transcription factor E2f requires viral E1A and E4 gene products for increased DNA-binding activity and functions to stimulate adenovirus E2A gene expressionAnalysis of trans activation by human papillomavirus type 16 E7 and adenovirus 12S E1A suggests a common mechanism.The adenovirus E4 gene, in addition to the E1A gene, is important for trans-activation of E2 transcription and for E2F activation.The regions important for the activator and repressor functions of herpes simplex virus type 1 alpha protein ICP27 map to the C-terminal half of the molecule.Multiple transcriptional regulatory domains in the human immunodeficiency virus type 1 long terminal repeat are involved in basal and E1A/E1B-induced promoter activity.An adenovirus type 5 E1A protein with a single amino acid substitution blocks wild-type E1A transactivationThree trans-acting regulatory proteins of herpes simplex virus modulate immediate-early gene expression in a pathway involving positive and negative feedback regulation.Repression of adenovirus early gene expression by coinfection with a temperature-sensitive mutant in the immediate-early gene of pseudorabies virus.Autoregulation of adenovirus E1A gene expressionEIa-mediated stimulation of the adenovirus EIII promoter involves an enhancer element within the nearby EIIa promoterUse of recombinant retroviruses to study the regulation of integrated adenovirus early promotersIdentification of sequence requirements and trans-acting functions necessary for regulated expression of a human cytomegalovirus early gene.
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P2860
An enhancer-like element in the adenovirus E2 promoter contains sequences essential for uninduced and E1A-induced transcription.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 1985
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
An enhancer-like element in th ...... and E1A-induced transcription.
@en
An enhancer-like element in th ...... and E1A-induced transcription.
@nl
type
label
An enhancer-like element in th ...... and E1A-induced transcription.
@en
An enhancer-like element in th ...... and E1A-induced transcription.
@nl
prefLabel
An enhancer-like element in th ...... and E1A-induced transcription.
@en
An enhancer-like element in th ...... and E1A-induced transcription.
@nl
P2093
P2860
P356
P1476
An enhancer-like element in th ...... and E1A-induced transcription.
@en
P2093
J R Nevins
M J Imperiale
P2860
P304
P356
10.1073/PNAS.82.2.381
P407
P577
1985-01-01T00:00:00Z