Identification of sequence requirements and trans-acting functions necessary for regulated expression of a human cytomegalovirus early gene.
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Activation of transcription of the human cytomegalovirus early UL4 promoter by the Ets transcription factor binding element.Effects of human cytomegalovirus major immediate-early proteins in controlling the cell cycle and inhibiting apoptosis: studies with ts13 cellsThe phosphorylation status of the serine-rich region of the human cytomegalovirus 86-kilodalton major immediate-early protein IE2/IEP86 affects temporal viral gene expression.Transcription factor Sp1 mediates cell-specific trans-activation of the human cytomegalovirus DNA polymerase gene promoter by immediate-early protein IE86 in glioblastoma U373MG cells.Defective growth correlates with reduced accumulation of a viral DNA replication protein after low-multiplicity infection by a human cytomegalovirus ie1 mutant.Phosphorylation of the human cytomegalovirus 86-kilodalton immediate-early protein IE2.An AP-1 binding site is the predominant cis-acting regulatory element in the 1.2-kilobase early RNA promoter of human cytomegalovirus.Construction of a rationally designed human cytomegalovirus variant encoding a temperature-sensitive immediate-early 2 protein.Inhibition of cyclooxygenase 2 blocks human cytomegalovirus replication.Role of the specific interaction of UL112-113 p84 with UL44 DNA polymerase processivity factor in promoting DNA replication of human cytomegalovirus.Functional properties of the human cytomegalovirus IE86 protein required for transcriptional regulation and virus replicationRole of regulatory elements and the MAPK/ERK or p38 MAPK pathways for activation of human cytomegalovirus gene expression.Strain variations in single amino acids of the 86-kilodalton human cytomegalovirus major immediate-early protein (IE2) affect its functional and biochemical properties: implications of dynamic protein conformation.Analysis of splice variants of the immediate-early 1 region of human cytomegalovirus.Neuron-specific activation of murine cytomegalovirus early gene e1 promoter in transgenic miceAnalysis and mapping of a family of 3'-coterminal transcripts containing coding sequences for human cytomegalovirus open reading frames UL93 through UL99.Differential effects of human cytomegalovirus on integrated and unintegrated human immunodeficiency virus sequencesGrowth kinetics of human cytomegalovirus are altered in monocyte-derived macrophages.The human cytomegalovirus UL98 gene transcription unit overlaps with the pp28 true late gene (UL99) and encodes a 58-kilodalton early protein.Multiple regulatory events influence human cytomegalovirus DNA polymerase (UL54) expression during viral infectionThe IE2 regulatory protein of human cytomegalovirus induces expression of the human transforming growth factor beta1 gene through an Egr-1 binding site.DNA immunization confers protection against murine cytomegalovirus infection.The role of ATF in regulating the human cytomegalovirus DNA polymerase (UL54) promoter during viral infection.TAF-like functions of human cytomegalovirus immediate-early proteinsIdentification of sequence elements in the human cytomegalovirus DNA polymerase gene promoter required for activation by viral gene products.The human cytomegalovirus 86-kilodalton immediate-early 2 protein: synthesis as a precursor polypeptide and interaction with a 75-kilodalton protein of probable viral origin.The effects of cytomegalovirus on human immunodeficiency virus replication in brain-derived cells correlate with permissiveness of the cells for each virusUse of recombinant virus to assess human cytomegalovirus early and late promoters in the context of the viral genome.Human cytomegalovirus immediate-early gene 2 protein interacts with itself and with several novel cellular proteinsSpliced transcripts of human cytomegalovirus.Structural organization, expression, and functional characterization of the murine cytomegalovirus immediate-early gene 3Human cytomegalovirus ie2 negatively regulates alpha gene expression via a short target sequence near the transcription start siteCharacterization of a human cytomegalovirus 1.6-kilobase late mRNA and identification of its putative protein product.Transactivation of the cytomegalovirus ICP36 gene promoter requires the alpha gene product TRS1 in addition to IE1 and IE2Characterization of human cytomegalovirus UL84 early gene and identification of its putative protein productThe functionally active IE2 immediate-early regulatory protein of human cytomegalovirus is an 80-kilodalton polypeptide that contains two distinct activator domains and a duplicated nuclear localization signalThe human cytomegalovirus 2.7-kilobase RNA promoter contains a functional binding site for the adenovirus major late transcription factor.Regulation of cytomegalovirus late-gene expression: differential use of three start sites in the transcriptional activation of ICP36 gene expressionThe IE2 gene products of human cytomegalovirus specifically down-regulate expression from the major immediate-early promoter through a target sequence located near the cap site.Transactivation of a human cytomegalovirus early promoter by gene products from the immediate-early gene IE2 and augmentation by IE1: mutational analysis of the viral proteins.
P2860
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P2860
Identification of sequence requirements and trans-acting functions necessary for regulated expression of a human cytomegalovirus early gene.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
1988年论文
@zh
1988年论文
@zh-cn
name
Identification of sequence req ...... an cytomegalovirus early gene.
@en
type
label
Identification of sequence req ...... an cytomegalovirus early gene.
@en
prefLabel
Identification of sequence req ...... an cytomegalovirus early gene.
@en
P2093
P2860
P1433
P1476
Identification of sequence req ...... man cytomegalovirus early gene
@en
P2093
D H Spector
D K Rabert
S I Staprans
P2860
P304
P407
P577
1988-09-01T00:00:00Z