Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation.
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Action and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological SynapseAdhesion protein networks reveal functions proximal and distal to cell-matrix contactsTalin Dependent Mechanosensitivity of Cell Focal AdhesionsCellular Biomechanics in Drug Screening and Evaluation: MechanopharmacologyVinculin controls talin engagement with the actomyosin machinery.Extracellular rigidity sensing by talin isoform-specific mechanical linkagesAll Subdomains of the Talin Rod Are Mechanically Vulnerable and May Contribute To Cellular MechanosensingCost-benefit analysis of the mechanisms that enable migrating cells to sustain motility upon changes in matrix environments.Cooperative Vinculin Binding to Talin Mapped by Time-Resolved Super Resolution Microscopy.Mechanical stability of talin rod controls cell migration and substrate sensing.Single-molecule force spectroscopy reveals force-enhanced binding of calcium ions by gelsolinForce is a signal that cells cannot ignore.Mechanical force antagonizes the inhibitory effects of RecX on RecA filament formation in Mycobacterium tuberculosis.Dynamics of equilibrium folding and unfolding transitions of titin immunoglobulin domain under constant forces.Molecular mechanism of vinculin activation and nanoscale spatial organization in focal adhesions.Talin determines the nanoscale architecture of focal adhesions.The mechanotransduction machinery at work at adherens junctions.Regulation of integrin-mediated adhesions.Multiscale mechanobiology: computational models for integrating molecules to multicellular systems.Disturbance-free rapid solution exchange for magnetic tweezers single-molecule studies.LD Motif Recognition by Talin: Structure of the Talin-DLC1 ComplexThe mechanical response of talin.Talin-KANK1 interaction controls the recruitment of cortical microtubule stabilizing complexes to focal adhesions.Drosophila vinculin is more harmful when hyperactive than absent, and can circumvent integrin to form adhesion complexes.How to Measure Molecular Forces in Cells: A Guide to Evaluating Genetically-Encoded FRET-Based Tension Sensors.Lighting Up the Force: Investigating Mechanisms of Mechanotransduction Using Fluorescent Tension Probes.The nucleus is a conserved mechanosensation and mechanoresponse organelle.Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix.Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch.Molecular mechanisms of mechanotransduction in integrin-mediated cell-matrix adhesion.Complement Receptors in Myeloid Cell Adhesion and Phagocytosis.Integrin-mediated mechanotransduction.The Nuclear Option: Evidence Implicating the Cell Nucleus in Mechanotransduction.Integration of Cadherin Adhesion and Cytoskeleton at Adherens Junctions.Alternative mechanisms for talin to mediate integrin functionMolecular stretching modulates mechanosensing pathways.Quantifying forces in cell biology.Talin - the master of integrin adhesions.Molecular Mechanoneurobiology: An Emerging Angle to Explore Neural Synaptic Functions.Zygotic vinculin is not essential for embryonic development in zebrafish.
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Mechanical activation of vinculin binding to talin locks talin in an unfolded conformation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 09 April 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Mechanical activation of vincu ...... n in an unfolded conformation.
@en
Mechanical activation of vincu ...... n in an unfolded conformation.
@nl
type
label
Mechanical activation of vincu ...... n in an unfolded conformation.
@en
Mechanical activation of vincu ...... n in an unfolded conformation.
@nl
prefLabel
Mechanical activation of vincu ...... n in an unfolded conformation.
@en
Mechanical activation of vincu ...... n in an unfolded conformation.
@nl
P2093
P2860
P50
P356
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P1476
Mechanical activation of vincu ...... n in an unfolded conformation.
@en
P2093
Michael P Sheetz
Mingxi Yao
P2860
P2888
P356
10.1038/SREP04610
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P577
2014-04-09T00:00:00Z
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P6179
1049525946