Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch.
about
Notch-Mediated Cell Adhesion4-Dimensional light-sheet microscopy to elucidate shear stress modulation of cardiac trabeculation.Small but Mighty: Nanoparticles Probe Cellular Signaling PathwaysMutational analysis of the Notch2 negative regulatory region identifies key structural elements for mechanical stability.Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors.Notch and Hippo signaling converge on Strawberry Notch 1 (Sbno1) to synergistically activate Cdx2 during specification of the trophectoderm.Constructing modular and universal single molecule tension sensor using protein G to study mechano-sensitive receptors.Context-Dependent Sensitivity to Mutations Disrupting the Structural Integrity of Individual EGF Repeats in the Mouse Notch Ligand DLL1.A Mechanogenetic Toolkit for Interrogating Cell Signaling in Space and Time.Defining Single Molecular Forces Required for Notch Activation Using Nano Yoyo.Muscle contraction is required to maintain the pool of muscle progenitors via YAP and NOTCH during fetal myogenesis.Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors.Structure and function of the Mind bomb E3 ligase in the context of Notch signal transduction.Analyzing Cell Surface Adhesion Remodeling in Response to Mechanical Tension Using Magnetic Beads.Chimeric antigen receptors: driving immunology towards synthetic biology.Notch: A multi-functional integrating system of microenvironmental signals.Notch Signaling and Alloreactivity.Roles of the cytoskeleton, cell adhesion and rho signalling in mechanosensing and mechanotransduction.Methods to investigate the structure and connectivity of the nervous system.A new mechanism for spatial pattern formation via lateral and protrusion-mediated lateral signalling.Context-dependent function of ROS in the vascular endothelium: The role of the Notch pathway and shear stress.Synthetic Immunology: Hacking Immune Cells to Expand Their Therapeutic Capabilities.The Canonical Notch Signaling Pathway: Structural and Biochemical Insights into Shape, Sugar, and Force.Reprogramming cellular functions with engineered membrane proteins.The Varied Roles of Notch in Cancer.Sequence-Directed Covalent Protein-DNA Linkages in a Single Step Using HUH-Tags.Combinatorial Antigen Targeting: Ideal T-Cell Sensing and Anti-Tumor Response.O-Glycosylation modulates the stability of epidermal growth factor-like repeats and thereby regulates Notch trafficking.A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self-renewal.Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity.Impact of external pneumatic compression target inflation pressure on transcriptome-wide RNA expression in skeletal muscle.Monitoring cell-cell contacts in vivo in transgenic animals.Ubiquitylation at the crossroads of development and disease.Development of an optimized synthetic Notch receptor as an in vivo cell-cell contact sensor.Tracing neuronal circuits in transgenic animals by transneuronal control of transcription (TRACT).Notch Signaling in Development, Tissue Homeostasis, and Disease.Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification.Mechanosensing and fibrosis.A non-canonical Notch complex regulates adherens junctions and vascular barrier function.Multiplexing molecular tension sensors reveals piconewton force gradient across talin-1.
P2860
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P2860
Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Mechanical Allostery: Evidence ...... oteolytic Activation of Notch.
@en
type
label
Mechanical Allostery: Evidence ...... oteolytic Activation of Notch.
@en
prefLabel
Mechanical Allostery: Evidence ...... oteolytic Activation of Notch.
@en
P2093
P2860
P1433
P1476
Mechanical Allostery: Evidence ...... oteolytic Activation of Notch.
@en
P2093
Brandon Zimmerman
Debbie G McArthur
Jiuhong Huang
Jon C Aster
Joseph J Loparo
Kittichoat Tiyanont
Laura J Miles
Stephen C Blacklow
P2860
P304
P356
10.1016/J.DEVCEL.2015.05.004
P407
P577
2015-06-04T00:00:00Z