Differential upregulation in DRG neurons of an α2δ-1 splice variant with a lower affinity for gabapentin after peripheral sensory nerve injury.
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Alternative RNA splicing: contribution to pain and potential therapeutic strategyMechanisms of the gabapentinoids and α 2 δ-1 calcium channel subunit in neuropathic painIncidence of Augmentation in Primary Restless Legs Syndrome Patients May Not Be That High: Evidence From A Systematic Review and Meta-AnalysisThe Physiology, Pathology, and Pharmacology of Voltage-Gated Calcium Channels and Their Future Therapeutic PotentialGenetic disruption of voltage-gated calcium channels in psychiatric and neurological disordersEmerging evidence for specific neuronal functions of auxiliary calcium channel α₂δ subunits.Impact of gabapentin on neuronal high voltage-activated Ca2+ channel properties of injured-side axotomized and adjacent uninjured dorsal root ganglions in a rat model of spinal nerve ligation.Voltage-gated calcium channels and their auxiliary subunits: physiology and pathophysiology and pharmacologyProteolytic maturation of α2δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels.Injury-induced maladaptation and dysregulation of calcium channel α2 δ subunit proteins and its contribution to neuropathic pain development.Calcium channel modulation as a target in chronic pain control.Thrombospondin-4 reduces binding affinity of [(3)H]-gabapentin to calcium-channel α2δ-1-subunit but does not interact with α2δ-1 on the cell-surface when co-expressed.Electrophysiological characterization of activation state-dependent Ca(v)2 channel antagonist TROX-1 in spinal nerve injured rats.Efficacy and Tolerability of Gabapentin in Adults with Sleep Disturbance in Medical Illness: A Systematic Review and Meta-analysis.Altered expression of the voltage-gated calcium channel subunit α₂δ-1: a comparison between two experimental models of epilepsy and a sensory nerve ligation model of neuropathic pain.The α2δ Subunit and Absence Epilepsy: Beyond Calcium Channels?Analysis of the long-term actions of gabapentin and pregabalin in dorsal root ganglia and substantia gelatinosa.Neuropathic pain-induced enhancement of spontaneous and pain-evoked neuronal activity in the periaqueductal gray that is attenuated by gabapentin.
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P2860
Differential upregulation in DRG neurons of an α2δ-1 splice variant with a lower affinity for gabapentin after peripheral sensory nerve injury.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 06 December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Differential upregulation in D ...... ripheral sensory nerve injury.
@en
Differential upregulation in D ...... ripheral sensory nerve injury.
@nl
type
label
Differential upregulation in D ...... ripheral sensory nerve injury.
@en
Differential upregulation in D ...... ripheral sensory nerve injury.
@nl
prefLabel
Differential upregulation in D ...... ripheral sensory nerve injury.
@en
Differential upregulation in D ...... ripheral sensory nerve injury.
@nl
P2093
P2860
P1433
P1476
Differential upregulation in D ...... ripheral sensory nerve injury.
@en
P2093
Anthony H Dickenson
Beatrice Lana
Bettina Schlick
Claudia S Bauer
Karen M Page
Leonor Goncalves
Stuart Martin
Wahida Rahman
Wendy S Pratt
P2860
P304
P356
10.1016/J.PAIN.2013.12.001
P407
P577
2013-12-06T00:00:00Z