Increased numbers of preexisting memory CD8 T cells and decreased T-bet expression can restrain terminal differentiation of secondary effector and memory CD8 T cells.
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CMV-Specific CD8 T Cell Differentiation and Localization: Implications for Adoptive TherapiesCD8(+) T-cell effector function and transcriptional regulation during HIV pathogenesisCharacterization of T-bet and eomes in peripheral human immune cellsT-bet and Eomes are differentially linked to the exhausted phenotype of CD8+ T cells in HIV infectionTranscriptional control of effector and memory CD8+ T cell differentiation.The interface between transcriptional and epigenetic control of effector and memory CD8⁺ T-cell differentiationHuman memory, but not naive, CD4+ T cells expressing transcription factor T-bet might drive rapid cytokine production.The tyrosine kinase Itk suppresses CD8+ memory T cell development in response to bacterial infection.Specificity and dynamics of effector and memory CD8 T cell responses in human tick-borne encephalitis virus infection.Accumulation of memory precursor CD8 T cells in regressing tumors following combination therapy with vaccine and anti-PD-1 antibody.HLA-A02:01-restricted epitopes identified from the herpes simplex virus tegument protein VP11/12 preferentially recall polyfunctional effector memory CD8+ T cells from seropositive asymptomatic individuals and protect humanized HLA-A*02:01 transgeniHeteroclitic XBP1 peptides evoke tumor-specific memory cytotoxic T lymphocytes against breast cancer, colon cancer, and pancreatic cancer cells.Generating CD8 T cell heterogeneity: attack of the clones.Phenotypic and functional characterization of herpes simplex virus glycoprotein B epitope-specific effector and memory CD8+ T cells from symptomatic and asymptomatic individuals with ocular herpesCD8 T cells recruited early in mouse polyomavirus infection undergo exhaustionc-IAP ubiquitin protein ligase activity is required for 4-1BB signaling and CD8(+) memory T-cell survival.Activation of the Hippo pathway by CTLA-4 regulates the expression of Blimp-1 in the CD8+ T cell.The transcription factors ZEB2 and T-bet cooperate to program cytotoxic T cell terminal differentiation in response to LCMV viral infection.Eomesodermin(lo) CTLA4(hi) Alloreactive CD8+ Memory T Cells Are Associated With Prolonged Renal Transplant Survival Induced by Regulatory Dendritic Cell Infusion in CTLA4 Immunoglobulin-Treated Nonhuman Primates.Memory CD8 T cells specific for plasmodia liver-stage antigens maintain protracted protection against malaria.Differential localization of T-bet and Eomes in CD8 T cell memory populations.The survival of memory CD8 T cells that is mediated by IL-15 correlates with sustained protection against malaria.Asymptomatic memory CD8+ T cells: from development and regulation to consideration for human vaccines and immunotherapeuticsHigh viral burden restricts short-lived effector cell number at late times postinfection through increased natural regulatory T cell expansion.Lenalidomide Polarizes Th1-specific Anti-tumor Immune Response and Expands XBP1 Antigen-Specific Central Memory CD3(+)CD8(+) T cells against Various Solid Tumors.Aging promotes acquisition of naive-like CD8+ memory T cell traits and enhanced functionalities.Lung airway-surveilling CXCR3(hi) memory CD8(+) T cells are critical for protection against influenza A virusHuman Asymptomatic Epitopes Identified from the Herpes Simplex Virus Tegument Protein VP13/14 (UL47) Preferentially Recall Polyfunctional Effector Memory CD44high CD62Llow CD8+ TEM Cells and Protect Humanized HLA-A*02:01 Transgenic Mice against OculPreexisting high frequencies of memory CD8+ T cells favor rapid memory differentiation and preservation of proliferative potential upon boosting.Protecting and rescuing the effectors: roles of differentiation and survival in the control of memory T cell development.Human memory CD8 T cell effector potential is epigenetically preserved during in vivo homeostasis.Mechanisms Underlying T Cell Immunosenescence: Aging and Cytomegalovirus Infection.The Balance between CD8+ T Cell-Mediated Clearance of AAV-Encoded Antigen in the Liver and Tolerance Is Dependent on the Vector Dose.Vaccination for Mycobacterium tuberculosis infection: reprogramming CD4 T-cell homing into the lung.T-bet Is Required for the Rapid Clearance of Attenuated Rabies Virus from Central Nervous System TissueFOXO1 opposition of CD8+ T cell effector programming confers early memory properties and phenotypic diversity.Memory T Cell Proliferation before Hepatitis C Virus Therapy Predicts Antiviral Immune Responses and Treatment Success.Transcription factor ELF4 promotes development and function of memory CD8(+) T cells in Listeria monocytogenes infection.Association between the genetic variations within TBX21 gene promoter and the clinicopathological characteristics of esophageal squamous cell carcinoma in a high-risk Chinese population.PD-1/PD-L1 pathway: an adaptive immune resistance mechanism to immunogenic chemotherapy in colorectal cancer.
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Increased numbers of preexisting memory CD8 T cells and decreased T-bet expression can restrain terminal differentiation of secondary effector and memory CD8 T cells.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 19 September 2011
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Increased numbers of preexisti ...... fector and memory CD8 T cells.
@en
Increased numbers of preexisti ...... fector and memory CD8 T cells.
@nl
type
label
Increased numbers of preexisti ...... fector and memory CD8 T cells.
@en
Increased numbers of preexisti ...... fector and memory CD8 T cells.
@nl
prefLabel
Increased numbers of preexisti ...... fector and memory CD8 T cells.
@en
Increased numbers of preexisti ...... fector and memory CD8 T cells.
@nl
P2093
P2860
P356
P1476
Increased numbers of preexisti ...... ffector and memory CD8 T cells
@en
P2093
Claudia X Dominguez
Jonathan H Chen
Susan M Kaech
Timothy W Hand
Weiguo Cui
P2860
P304
P356
10.4049/JIMMUNOL.1002145
P407
P577
2011-09-19T00:00:00Z