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Awakening lineage potential by Ikaros-mediated transcriptional priming.

Awakening lineage potential by Ikaros-mediated transcriptional priming.

http://www.wikidata.org/entity/Q37714143

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Serine phosphorylation by SYK is critical for nuclear localization and transcription factor function of Ikaros Selective regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies Myh7b/miR-499 gene expression is transcriptionally regulated by MRFs and Eos Regulatory phosphorylation of Ikaros by Bruton's tyrosine kinase Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongation Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis.Peripheral natural killer cell maturation depends on the transcription factor Aiolos Gfi1 and gfi1b repress rag transcription in plasmacytoid dendritic cells in vitro The IKAROS interaction with a complex including chromatin remodeling and transcription elongation activities is required for hematopoiesis.Expression of Ik6 and Ik8 Isoforms and Their Association with Relapse and Death in Mexican Children with Acute Lymphoblastic Leukemia Efficacy of Retinoids in IKZF1-Mutated BCR-ABL1 Acute Lymphoblastic Leukemia.Alternative Splice Variants Modulates Dominant-Negative Function of Helios in T-Cell Leukemia.Higher-order orchestration of hematopoiesis: is cohesin a new player?Ikaros Inhibits Group 3 Innate Lymphoid Cell Development and Function by Suppressing the Aryl Hydrocarbon Receptor Pathway.Ikaros limits basophil development by suppressing C/EBP-α expression.Superenhancer reprogramming drives a B-cell-epithelial transition and high-risk leukemia.Transcriptional regulators dictate innate lymphoid cell fates.Epstein-Barr virus utilizes Ikaros in regulating its latent-lytic switch in B cells.Switching of the relative dominance between feedback mechanisms in lipopolysaccharide-induced NF-κB signaling Transcription factor networks in dendritic cell development.Staying innate: transcription factor maintenance of innate lymphoid cell identity.Dominant-negative Ikaros cooperates with BCR-ABL1 to induce human acute myeloid leukemia in xenografts.Direct protein interactions are responsible for Ikaros-GATA and Ikaros-Cdk9 cooperativeness in hematopoietic cells Normal hematologic parameters and fetal hemoglobin silencing with heterozygous IKZF1 mutations Mucocutaneous inflammation in the Ikaros Family Zinc Finger 1-keratin 5-specific transgenic mice.

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Awakening lineage potential by Ikaros-mediated transcriptional priming.

http://www.wikidata.org/entity/Q37714143

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 17 March 2010

@en

vedecký článok

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vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Awakening lineage potential by Ikaros-mediated transcriptional priming.

@en

Awakening lineage potential by Ikaros-mediated transcriptional priming.

@nl

type

label

Awakening lineage potential by Ikaros-mediated transcriptional priming.

@en

Awakening lineage potential by Ikaros-mediated transcriptional priming.

@nl

prefLabel

Awakening lineage potential by Ikaros-mediated transcriptional priming.

@en

Awakening lineage potential by Ikaros-mediated transcriptional priming.

@nl

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J.COI.2010.02.011

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Current Opinion in Immunology

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Awakening lineage potential by Ikaros-mediated transcriptional priming.

@en

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Katia Georgopoulos

http://www.w3.org/2001/XMLSchema#string

Samuel Yao-Ming Ng

http://www.w3.org/2001/XMLSchema#string

Toshimi Yoshida

http://www.w3.org/2001/XMLSchema#string

P2860

A bivalent chromatin structure marks key developmental genes in embryonic stem cells

Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes

The role of the Ikaros gene in lymphocyte development and homeostasis

Ly6d marks the earliest stage of B-cell specification and identifies the branchpoint between B-cell and T-cell development

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells.

Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation.

Genome-wide lineage-specific transcriptional networks underscore Ikaros-dependent lymphoid priming in hematopoietic stem cells.

The evolution of adaptive immune systems.

Predominant interaction of both Ikaros and Helios with the NuRD complex in immature thymocytes.

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154-160

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scholarly article

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10.1016/J.COI.2010.02.011

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2

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22

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2010-03-17T00:00:00Z

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