p53 and NF-κB coregulate proinflammatory gene responses in human macrophages. - Wikidata - wikimedia - TriplyDB

p53 and NF-κB coregulate proinflammatory gene responses in human macrophages.

p53 and NF-κB coregulate proinflammatory gene responses in human macrophages.

http://www.wikidata.org/entity/Q37714779

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Transcriptional Activation of Inflammatory Genes: Mechanistic Insight into Selectivity and Diversity The Double Role of p53 in Cancer and Autoimmunity and Its Potential as Therapeutic Target Immunomodulatory Function of the Tumor Suppressor p53 in Host Immune Response and the Tumor Microenvironment Interleukin 6 augments lung cancer chemotherapeutic resistance via ataxia-telangiectasia mutated/NF-kappaB pathway activation A unique role for p53 in the regulation of M2 macrophage polarization p53 amplifies Toll-like receptor 5 response in human primary and cancer cells through interaction with multiple signal transduction pathways RelA NF-κB subunit activation as a therapeutic target in diffuse large B-cell lymphoma.Emerging roles of p53 and other tumour-suppressor genes in immune regulation Radiotherapy-Associated Long-term Modification of Expression of the Inflammatory Biomarker Genes ARG1, BCL2L1, and MYC.New perspective on targeting the tumor suppressor p53 pathway in the tumor microenvironment to enhance the efficacy of immunotherapy.Low-dose radiation accelerates aging of the T-cell receptor repertoire in CBA/Ca mice.Betulinic Acid-Mediated Apoptosis in Human Prostate Cancer Cells Involves p53 and Nuclear Factor-Kappa B (NF-κB) Pathways.Insulin-induced cytokine production in macrophages causes insulin resistance in hepatocytes.CD146 attenuation in cancer-associated fibroblasts promotes pancreatic cancer progression.GDF15 derived from both tumor-associated macrophages and esophageal squamous cell carcinomas contributes to tumor progression via Akt and Erk pathways.Cooperative interactions between p53 and NFκB enhance cell plasticity.Modulating Both Tumor Cell Death and Innate Immunity Is Essential for Improving Radiation Therapy Effectiveness.p53 isoforms regulate astrocyte-mediated neuroprotection and neurodegeneration.p16(Ink4a) and senescence-associated β-galactosidase can be induced in macrophages as part of a reversible response to physiological stimuli.cMyc-p53 feedback mechanism regulates the dynamics of T lymphocytes in the immune response.Brief mechanical ventilation causes differential epithelial repair along the airways of fetal, preterm lambs A new inflammatory role for p53 in human macrophages.Macrophage biology plays a central role during ionizing radiation-elicited tumor response.∆133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling.The novel p53 target TNFAIP8 variant 2 is increased in cancer and offsets p53-dependent tumor suppression.Deficiency of monoclonal non-specific suppressor factor beta (MNSFB) promotes pregnancy loss in mice.Microenvironment-Cell Nucleus Relationship in the Context of Oxidative Stress.Oncogenes in immune cells as potential therapeutic targets.Methotrexate selectively targets human proinflammatory macrophages through a thymidylate synthase/p53 axis.MDM2 Overexpression Modulates the Angiogenesis-Related Gene Expression Profile of Prostate Cancer Cells.The p53-S100A2 Positive Feedback Loop Negatively Regulates Epithelialization in Cutaneous Wound Healing.3D micro-environment regulates NF-κβ dependent adhesion to induce monocyte differentiation Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage Revealing a human p53 universe RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulated by NF-κB and p53 transcription factors in cells exposed to high doses of ionizing radiation

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p53 and NF-κB coregulate proinflammatory gene responses in human macrophages.

http://www.wikidata.org/entity/Q37714779

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on April 2014

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

p53 and NF-κB coregulate proinflammatory gene responses in human macrophages.

@en

p53 and NF-κB coregulate proinflammatory gene responses in human macrophages.

@nl

type

label

p53 and NF-κB coregulate proinflammatory gene responses in human macrophages.

@en

p53 and NF-κB coregulate proinflammatory gene responses in human macrophages.

@nl

prefLabel

p53 and NF-κB coregulate proinflammatory gene responses in human macrophages.

@en

p53 and NF-κB coregulate proinflammatory gene responses in human macrophages.

@nl

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0008-5472.CAN-13-1070

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Cancer Research

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p53 and NF-κB coregulate proinflammatory gene responses in human macrophages.

@en

P2093

Daniel Menendez

http://www.w3.org/2001/XMLSchema#string

Erin L Kirk

http://www.w3.org/2001/XMLSchema#string

Julie M Lowe

http://www.w3.org/2001/XMLSchema#string

Melissa A Troester

http://www.w3.org/2001/XMLSchema#string

Pierre R Bushel

http://www.w3.org/2001/XMLSchema#string

P2860

Mdm2 promotes the rapid degradation of p53

Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion

Transcription factors NF-IL6 and NF-kappa B synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8

Regulation of tumor necrosis factor alpha transcription in macrophages: involvement of four kappa B-like motifs and of constitutive and inducible forms of NF-kappa B

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor

IKKbeta links inflammation and tumorigenesis in a mouse model of colitis-associated cancer

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

Crosstalk in NF-κB signaling pathways

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2182-2192

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scholarly article

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10.1158/0008-5472.CAN-13-1070

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P433

8

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74

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Stavros Garantziotis

Michael A Resnick

Michael B Fessler

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2014-04-01T00:00:00Z

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24737129

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3994464

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