Defined neurofilament, tau, and beta-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques.
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P3 beta-amyloid peptide has a unique and potentially pathogenic immunohistochemical profile in Alzheimer's disease brainFamilial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filamentsNeuropathology and apolipoprotein E profile of aged chimpanzees: implications for Alzheimer diseaseEpitope map of neurofilament protein domains in cortical and peripheral nervous system Lewy bodies.Quantitative neuropathology: an update on automated methodologies and implications for large scale cohorts.Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaquesA critical analysis of postulated pathogenetic mechanisms in amyloidogenesis.Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation.Amyloid beta protein deposition in normal aging has the same characteristics as that in Alzheimer's disease. Predominance of A beta 42(43) and association of A beta 40 with cored plaquesFull-length amyloid-beta (1-42(43)) and amino-terminally modified and truncated amyloid-beta 42(43) deposit in diffuse plaques.Chemical and immunological heterogeneity of fibrillar amyloid in plaques of Alzheimer's disease and Down's syndrome brains revealed by confocal microscopy.Molecular features of hypothalamic plaques in Alzheimer's disease.Distribution of beta/A4 protein and amyloid precursor protein in hereditary cerebral hemorrhage with amyloidosis-Dutch type and Alzheimer's disease.Alzheimer disease A68 proteins injected into rat brain induce codeposits of beta-amyloid, ubiquitin, and alpha 1-antichymotrypsin.Plasma amyloid beta measurements - a desired but elusive Alzheimer's disease biomarkerTissue transglutaminase, protein cross-linking and Alzheimer's disease: review and views.Increased neuronal beta-amyloid precursor protein expression in human temporal lobe epilepsy: association with interleukin-1 alpha immunoreactivityAltered tau and neurofilament proteins in neuro-degenerative diseases: diagnostic implications for Alzheimer's disease and Lewy body dementias.The role of synaptic proteins in the pathogenesis of disorders of the central nervous system.Alzheimer's amyloid precursor protein-positive degenerative neurites exist even within kuru plaques not specific to Alzheimer's disease.Antibodies to non-beta regions of the beta-amyloid precursor protein detect a subset of senile plaques.Light and electron microscopic localization of beta-amyloid protein in muscle biopsies of patients with inclusion-body myositis.Tangle-associated neuritic clusters. A new lesion in Alzheimer's disease and aging suggests that aggregates of dystrophic neurites are not necessarily associated with beta/A4An antibody against phosphorylated neurofilaments identifies a subset of damaged association axons in Alzheimer's disease.Beta-Amyloid peptide and amyloid precursor proteins in olfactory mucosa of patients with Alzheimer's disease, Parkinson's disease, and Down syndrome.Alzheimer's disease. Beta-amyloid precursor protein expression in the nucleus basalis of Meynert.The ameliorating effects of luteolin on beta-amyloid-induced impairment of water maze performance and passive avoidance in rats.Colocalization of amino terminal and A4 (beta-amyloid) antigens in Alzheimer plaques: evidence for coordinated processing of the amyloid precursor protein.Low amyloid (Abeta) plaque load and relative predominance of diffuse plaques distinguish argyrophilic grain disease from Alzheimer's disease.An extensive network of PHF tau-rich dystrophic neurites permeates neocortex and nearly all neuritic and diffuse amyloid plaques in Alzheimer disease.Tomoregulin-2 is found extensively in plaques in Alzheimer's disease brain.Relative increase in Alzheimer's disease of soluble forms of cerebral Abeta amyloid protein precursor containing the Kunitz protease inhibitory domain.Long-term Ameliorative Effects of the Antidepressant Fluoxetine Exposure on Cognitive Deficits in 3 × TgAD Mice.Reduction of autophagy markers mediated protective effects of JNK inhibitor and bucladesine on memory deficit induced by Aβ in rats.Morphological and biochemical analyses of amyloid plaque core proteins purified from Alzheimer disease brain tissue.Distribution of amyloid beta protein precursor in the Alzheimer's disease brain.DNAJC5 facilitates USP19-dependent unconventional secretion of misfolded cytosolic proteins.A comparison of β-amyloid (Aβ) deposition in the medial temporal lobe in late-onset sporadic Alzheimer's disease, and Down's syndrome
P2860
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P2860
Defined neurofilament, tau, and beta-amyloid precursor protein epitopes distinguish Alzheimer from non-Alzheimer senile plaques.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 1990
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Defined neurofilament, tau, an ...... non-Alzheimer senile plaques.
@en
Defined neurofilament, tau, an ...... non-Alzheimer senile plaques.
@nl
type
label
Defined neurofilament, tau, an ...... non-Alzheimer senile plaques.
@en
Defined neurofilament, tau, an ...... non-Alzheimer senile plaques.
@nl
prefLabel
Defined neurofilament, tau, an ...... non-Alzheimer senile plaques.
@en
Defined neurofilament, tau, an ...... non-Alzheimer senile plaques.
@nl
P2093
P2860
P356
P1476
Defined neurofilament, tau, an ...... m non-Alzheimer senile plaques
@en
P2093
B D Greenberg
J Q Trojanowski
M L Schmidt
S K Sharma
P2860
P304
P356
10.1073/PNAS.87.6.2249
P407
P577
1990-03-01T00:00:00Z