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Directed migration of positively selected thymocytes visualized in real time.The Contribution of Chemokines and Migration to the Induction of Central Tolerance in the ThymusMaturation and migration of murine CD4 single positive thymocytes and thymic emigrantsThe production of alpha/beta and gamma/delta double negative (DN) T-cells and their role in the maintenance of pregnancyExpression of the Bcl-2 family member A1 is developmentally regulated in T cellsQuantitative and functional expression of somatostatin receptor subtypes in human thymocytesSpare PRELI gene loci: failsafe chromosome insurance?A mutation in a chromosome condensin II subunit, kleisin beta, specifically disrupts T cell developmentDynamic control of β1 integrin adhesion by the plexinD1-sema3E axis.Altered bone marrow lymphopoiesis and interleukin-6-dependent inhibition of thymocyte differentiation contribute to thymic atrophy during Trypanosoma cruzi infection.Efficient intrathymic gene transfer following in situ administration of a rAAV serotype 8 vector in mice and nonhuman primates.Thymic emigration: when and how T cells leave home.Human T-Cell Development and Thymic Egress: An Infectious Disease PerspectiveOne naive T cell, multiple fates in CD8+ T cell differentiation.Identification of dendritic cells, B cell and T cell subsets in Tasmanian devil lymphoid tissue; evidence for poor immune cell infiltration into devil facial tumors.The ability to rearrange dual TCRs enhances positive selection, leading to increased Allo- and Autoreactive T cell repertoires.Review article: thymus organ cultures and T-cell receptor repertoire development.Transcriptomic analysis supports similar functional roles for the two thymuses of the tammar wallaby.The role of the thymus in tolerance.Both positive and negative effects on immune responses by expression of a second class II MHC molecule.Bclx regulates the survival of double-positive thymocytes.Without peripheral interference, thymic deletion is mediated in a cohort of double-positive cells without classical activation.The activation threshold of CD4+ T cells is defined by TCR/peptide-MHC class II interactions in the thymic medullaPositive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgene.Genetic prevention of lymphoma in p53 knockout mice allows the early development of p53-related sarcomasLipid phosphate phosphatase 3 enables efficient thymic egress.Apoptosis and T-cell repertoire selection in the thymus.Regulation of DNA methylation dictates Cd4 expression during the development of helper and cytotoxic T cell lineages.Spontaneous apoptosis in human thymocytes.Expression of bcl-2 in fetal tissues suggests a role in morphogenesis.Cross-linking of T-cell receptors on double-positive thymocytes induces a cytokine-mediated stromal activation process linked to cell deathThe cell death inhibitor Bcl-2 and its homologues influence control of cell cycle entryBax alpha perturbs T cell development and affects cell cycle entry of T cellsTwo distinct pathways of positive selection for thymocytes.Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunityAn MHC-linked locus modulates thymic differentiation of CD4+CD25+Foxp3+ regulatory T lymphocytes.Thymic emigration revisitedThe kinetics of T cell antigen receptor expression by subgroups of CD4+8+ thymocytes: delineation of CD4+8+3(2+) thymocytes as post-selection intermediates leading to mature T cells.Identifying T Cell Receptors from High-Throughput Sequencing: Dealing with Promiscuity in TCRα and TCRβ Pairing.Lineage relationships and developmental kinetics of immature thymocytes: CD3, CD4, and CD8 acquisition in vivo and in vitro
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 1990
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Kinetics of mature T-cell development in the thymus.
@en
Kinetics of mature T-cell development in the thymus.
@nl
type
label
Kinetics of mature T-cell development in the thymus.
@en
Kinetics of mature T-cell development in the thymus.
@nl
prefLabel
Kinetics of mature T-cell development in the thymus.
@en
Kinetics of mature T-cell development in the thymus.
@nl
P2093
P2860
P356
P1476
Kinetics of mature T-cell development in the thymus.
@en
P2093
P2860
P304
P356
10.1073/PNAS.87.7.2579
P407
P577
1990-04-01T00:00:00Z