Bax alpha perturbs T cell development and affects cell cycle entry of T cells
about
A dual role of cyclin E in cell proliferation and apoptosis may provide a target for cancer therapyLight induced apoptosis is accelerated in transgenic retina overexpressing human EAT/mcl-1, an anti-apoptotic bcl-2 related geneAccelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice.Disrupted differentiation and oncogenic transformation of lymphoid progenitors in E2A-HLF transgenic miceGene expression profiling of murine T-cell lymphoblastic lymphoma identifies deregulation of S-phase initiating genes.Deletion of p37Ing1 in mice reveals a p53-independent role for Ing1 in the suppression of cell proliferation, apoptosis, and tumorigenesis.The anti-apoptosis function of Bcl-2 can be genetically separated from its inhibitory effect on cell cycle entryA link between cell cycle and cell death: Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis.Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation.Higher expression of Bax in regulatory T cells increases vascular inflammation.Overexpression of Bcl2 in osteoblasts inhibits osteoblast differentiation and induces osteocyte apoptosis.Proteolytic cleavage of cyclin E leads to inactivation of associated kinase activity and amplification of apoptosis in hematopoietic cells.Bax expression measured by AQUAnalysis is an independent prognostic marker in oral squamous cell carcinoma.PARP-2 deficiency affects the survival of CD4+CD8+ double-positive thymocytes.Buffy, a Drosophila Bcl-2 protein, has anti-apoptotic and cell cycle inhibitory functions.Overexpression of bax associated with mutations in the loop-sheet-helix motif of p53DNA-damage response network at the crossroads of cell-cycle checkpoints, cellular senescence and apoptosisBax-induced apoptotic cell death.Loss of Bcl-2 in invasive breast cancer is associated with high rates of cell death, but also with increased proliferative activityBad can act as a key regulator of T cell apoptosis and T cell development.The cyclin-dependent kinase Cdk2 regulates thymocyte apoptosis.The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential.The action of Bax and bcl-2 on T cell selectionAsymmetric thymocyte death underlies the CD4:CD8 T-cell ratio in the adaptive immune systemManganese superoxide dismutase gene dosage affects chromosomal instability and tumor onset in a mouse model of T cell lymphoma.Non-apoptotic functions of BCL-2 family proteins.Bcl-xL/Bcl-2 coordinately regulates apoptosis, cell cycle arrest and cell cycle entry.c-Myb regulates the proliferation of immature thymocytes following beta-selection.G0 function of BCL2 and BCL-xL requires BAX, BAK, and p27 phosphorylation by Mirk, revealing a novel role of BAX and BAK in quiescence regulation.Bcl2 deficiency activates FoxO through Akt inactivation and accelerates osteoblast differentiationBcl-2 activates a programme of premature senescence in human carcinoma cells.The pro-apoptotic BAX protein influences cell growth and differentiation from the nucleus in healthy interphasic cells.The Bcl-2 family pro-apoptotic molecule, BNIP3 regulates activation-induced cell death of effector cytotoxic T lymphocytes.Dynamic Reorganization of the Cytoskeleton during Apoptosis: The Two Coffins Hypothesis.
P2860
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P2860
Bax alpha perturbs T cell development and affects cell cycle entry of T cells
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Bax alpha perturbs T cell development and affects cell cycle entry of T cells
@ast
Bax alpha perturbs T cell development and affects cell cycle entry of T cells
@en
type
label
Bax alpha perturbs T cell development and affects cell cycle entry of T cells
@ast
Bax alpha perturbs T cell development and affects cell cycle entry of T cells
@en
prefLabel
Bax alpha perturbs T cell development and affects cell cycle entry of T cells
@ast
Bax alpha perturbs T cell development and affects cell cycle entry of T cells
@en
P2093
P2860
P1433
P1476
Bax alpha perturbs T cell development and affects cell cycle entry of T cells
@en
P2093
P2860
P304
P356
10.1002/J.1460-2075.1996.TB01091.X
P407
P577
1996-12-01T00:00:00Z