The BRRF1 early gene of Epstein-Barr virus encodes a transcription factor that enhances induction of lytic infection by BRLF1.
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Regulation of the latent-lytic switch in Epstein-Barr virusEpstein-Barr virus lytic reactivation regulation and its pathogenic role in carcinogenesisThe B-cell specific transcription factor, Oct-2, promotes Epstein-Barr virus latency by inhibiting the viral immediate-early protein, BZLF1Methylation-dependent binding of the epstein-barr virus BZLF1 protein to viral promotersSumoylation of the Epstein-Barr virus BZLF1 protein inhibits its transcriptional activity and is regulated by the virus-encoded protein kinase.Epstein-Barr virus WZhet DNA can induce lytic replication in epithelial cells in vitro, although WZhet is not detectable in many human tissues in vivo.Epstein-Barr virus lytic infection is required for efficient production of the angiogenesis factor vascular endothelial growth factor in lymphoblastoid cell lines.Epstein-Barr virus lytic infection contributes to lymphoproliferative disease in a SCID mouse model.The Epstein-Barr virus BZLF1 protein inhibits tumor necrosis factor receptor 1 expression through effects on cellular C/EBP proteinsEpstein-Barr virus-specific methylation of human genes in gastric cancer cells.The Epstein-Barr virus BRRF1 protein, Na, induces lytic infection in a TRAF2- and p53-dependent mannerCellular transcription factor Oct-1 interacts with the Epstein-Barr virus BRLF1 protein to promote disruption of viral latencyThe virion-associated open reading frame 49 of murine gammaherpesvirus 68 promotes viral replication both in vitro and in vivo as a derepressor of RTA.Differentiation-Dependent KLF4 Expression Promotes Lytic Epstein-Barr Virus Infection in Epithelial CellsKnockout of Epstein-Barr virus BPLF1 retards B-cell transformation and lymphoma formation in humanized mice.The cellular ataxia telangiectasia-mutated kinase promotes epstein-barr virus lytic reactivation in response to multiple different types of lytic reactivation-inducing stimuli5-hydroxymethylation of the EBV genome regulates the latent to lytic switch.Viral genome methylation differentially affects the ability of BZLF1 versus BRLF1 to activate Epstein-Barr virus lytic gene expression and viral replication.Negative autoregulation of Epstein-Barr virus (EBV) replicative gene expression by EBV SM protein.Structure of the Open Reading Frame 49 Protein Encoded by Kaposi's Sarcoma-Associated Herpesvirus.Epstein-Barr virus utilizes Ikaros in regulating its latent-lytic switch in B cells.Epstein-Barr virus LF2 protein regulates viral replication by altering Rta subcellular localization.The Epstein-Barr virus (EBV)-encoded protein kinase, EBV-PK, but not the thymidine kinase (EBV-TK), is required for ganciclovir and acyclovir inhibition of lytic viral productionSimian virus 40 T/t antigens and lamin A/C small interfering RNA rescue the phenotype of an Epstein-Barr virus protein kinase (BGLF4) mutant.The Epstein-Barr Virus BRRF1 Gene Is Dispensable for Viral Replication in HEK293 cells and Transformation.Identification and characterization of the Orf49 protein of Kaposi's sarcoma-associated herpesvirus.Cohesins repress Kaposi's sarcoma-associated herpesvirus immediate early gene transcription during latency.The Rad6/18 ubiquitin complex interacts with the Epstein-Barr virus deubiquitinating enzyme, BPLF1, and contributes to virus infectivity.The ORF49 protein of murine gammaherpesvirus 68 cooperates with RTA in regulating virus replication.Epstein-Barr Virus Hijacks DNA Damage Response Transducers to Orchestrate Its Life Cycle.Investigating genetic-and-epigenetic networks, and the cellular mechanisms occurring in Epstein-Barr virus-infected human B lymphocytes via big data mining and genome-wide two-sided NGS data identificationStructure-based mechanism of action of a viral poly(ADP-ribose) polymerase 1-interacting protein facilitating virus replication
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The BRRF1 early gene of Epstein-Barr virus encodes a transcription factor that enhances induction of lytic infection by BRLF1.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on May 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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The BRRF1 early gene of Epstei ...... n of lytic infection by BRLF1.
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The BRRF1 early gene of Epstei ...... n of lytic infection by BRLF1.
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type
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The BRRF1 early gene of Epstei ...... n of lytic infection by BRLF1.
@en
The BRRF1 early gene of Epstei ...... n of lytic infection by BRLF1.
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The BRRF1 early gene of Epstei ...... n of lytic infection by BRLF1.
@en
The BRRF1 early gene of Epstei ...... n of lytic infection by BRLF1.
@nl
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The BRRF1 early gene of Epstei ...... on of lytic infection by BRLF1
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Alain Sergeant
Gregory K Hong
Shannon C Kenney
Thomas E Morrison
Wen-Hai Feng
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10.1128/JVI.78.10.4983-4992.2004
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2004-05-01T00:00:00Z