CD133+ cells contribute to radioresistance via altered regulation of DNA repair genes in human lung cancer cells.
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Cellular Pathways in Response to Ionizing Radiation and Their Targetability for Tumor RadiosensitizationGalectin-1 is overexpressed in CD133+ human lung adenocarcinoma cells and promotes their growth and invasiveness.IL-6 signaling promotes DNA repair and prevents apoptosis in CD133+ stem-like cells of lung cancer after radiation.High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant.Polarized cell migration induces cancer type-specific CD133/integrin/Src/Akt/GSK3β/β-catenin signaling required for maintenance of cancer stem cell properties.Investigating the Radioresistant Properties of Lung Cancer Stem Cells in the Context of the Tumor MicroenvironmentRadiation induces the generation of cancer stem cells: A novel mechanism for cancer radioresistanceInduction of metastasis, cancer stem cell phenotype, and oncogenic metabolism in cancer cells by ionizing radiation.The molecular mechanisms underlying the therapeutic resistance of cancer stem cells.The role of cancer stem cells in tumor heterogeneity and resistance to therapy.Cooperative effect of chidamide and chemotherapeutic drugs induce apoptosis by DNA damage accumulation and repair defects in acute myeloid leukemia stem and progenitor cells.DNA damage responses in cancer stem cells: Implications for cancer therapeutic strategiesApoptotic and genotoxic effects of low-intensity ultrasound on healthy and leukemic human peripheral mononuclear blood cells.Tumor Tissue Analogs for the Assessment of Radioresistance in Cancer Stem Cells.Carbonic Anhydrase IX (CAIX), Cancer, and Radiation Responsiveness.DNA Repair.Clinically relevant inflammatory breast cancer patient-derived xenograft-derived ex vivo model for evaluation of tumor-specific therapies.
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CD133+ cells contribute to radioresistance via altered regulation of DNA repair genes in human lung cancer cells.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 January 2014
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CD133+ cells contribute to rad ...... es in human lung cancer cells.
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CD133+ cells contribute to rad ...... es in human lung cancer cells.
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CD133+ cells contribute to rad ...... es in human lung cancer cells.
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CD133+ cells contribute to rad ...... es in human lung cancer cells.
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CD133+ cells contribute to rad ...... es in human lung cancer cells.
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CD133+ cells contribute to rad ...... es in human lung cancer cells.
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P2093
P2860
P1476
CD133+ cells contribute to rad ...... es in human lung cancer cells.
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P2093
Amar Desai
Bryan Webb
Stanton L Gerson
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P304
P356
10.1016/J.RADONC.2013.10.040
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2014-01-16T00:00:00Z