Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability. - Wikidata - wikimedia - TriplyDB

Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability.

Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability.

http://www.wikidata.org/entity/Q37733187

about

Wnt/beta-catenin signaling and small molecule inhibitors Amyloid precursor protein modulates beta-catenin degradation Cellular mechanisms of γ-secretase substrate selection, processing and toxicity Novel plasticity rule can explain the development of sensorimotor intelligence.Gamma-secretase-dependent and -independent effects of presenilin1 on beta-catenin.Tcf-4 transcriptional activity Pharmacological and genetic reversal of age-dependent cognitive deficits attributable to decreased presenilin function GABAρ subunits confer a bicuculline-insensitive component to GFAP+ cells of cerebellum.Presenilin-1 Dependent Neurogenesis Regulates Hippocampal Learning and Memory.Amyloid-β production via cleavage of amyloid-β protein precursor is modulated by cell density.Neural activity and CaMKII protect mitochondria from fragmentation in aging Caenorhabditis elegans neurons.Interactome analyses of mature γ-secretase complexes reveal distinct molecular environments of presenilin (PS) paralogs and preferential binding of signal peptide peptidase to PS2.Toward structural elucidation of the gamma-secretase complex.Presenilin: RIP and beyond.Molecular aspects of microcystin-induced hepatotoxicity and hepatocarcinogenesis.Review: disruption of the postsynaptic density in Alzheimer's disease and other neurodegenerative dementias.The way Wnt works: components and mechanism.p120 catenin recruits cadherins to gamma-secretase and inhibits production of Abeta peptide.Interleukin-1 receptor type 1 is a substrate for gamma-secretase-dependent regulated intramembrane proteolysis.Presenilin-1 is an unprimed glycogen synthase kinase-3beta substrate.Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference.Neuroscience. Plasticity in the neurotransmitter repertoire.Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy.Mutational re-modeling of di-aspartyl intramembrane proteases: uncoupling physiologically-relevant activities from those associated with Alzheimer's disease.

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Cadherins mediate both the association between PS1 and beta-catenin and the effects of PS1 on beta-catenin stability.

http://www.wikidata.org/entity/Q37733187

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 26 August 2005

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Cadherins mediate both the ass ...... PS1 on beta-catenin stability.

@en

Cadherins mediate both the ass ...... PS1 on beta-catenin stability.

@nl

type

label

Cadherins mediate both the ass ...... PS1 on beta-catenin stability.

@en

Cadherins mediate both the ass ...... PS1 on beta-catenin stability.

@nl

prefLabel

Cadherins mediate both the ass ...... PS1 on beta-catenin stability.

@en

Cadherins mediate both the ass ...... PS1 on beta-catenin stability.

@nl

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Journal of Biological Chemistry

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Cadherins mediate both the ass ...... PS1 on beta-catenin stability.

@en

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Anastasios Georgakopoulos

http://www.w3.org/2001/XMLSchema#string

Claudia M Litterst

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Geo Serban

http://www.w3.org/2001/XMLSchema#string

Junichi Shioi

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Lia Baki

http://www.w3.org/2001/XMLSchema#string

Nikolaos K Robakis

http://www.w3.org/2001/XMLSchema#string

Zen Kouchi

http://www.w3.org/2001/XMLSchema#string

P2860

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions.

The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin

Presenilin 1 interaction in the brain with a novel member of the Armadillo family

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

Wnt signaling and cancer

Direct interaction of Alzheimer's disease-related presenilin 1 with armadillo protein p0071

p120(ctn) binds to the membrane-proximal region of the E-cadherin cytoplasmic domain and is involved in modulation of adhesion activity

A CBP binding transcriptional repressor produced by the PS1/epsilon-cleavage of N-cadherin is inhibited by PS1 FAD mutations

Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis

Intercellular adhesion, signalling and the cytoskeleton

P304

36007-36012

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scholarly article

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10.1074/JBC.M507503200

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P433

43

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280

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2005-08-26T00:00:00Z

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16126725

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4005066

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