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Alternative expression of TCRζ related genes in patients with chronic myeloid leukemiaDiversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular PerspectivesFunctional roles of Syk in macrophage-mediated inflammatory responsesDouble-negative T cells during HIV/SIV infections: potential pinch hitters in the T-cell lineupSuper-resolution characterization of TCR-dependent signaling clustersCIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes InfectionDistinct Mechanisms Regulate Lck Spatial Organization in Activated T Cells.Time-Course Study of the Transcriptome of Peripheral Blood Mononuclear Cells (PBMCs) from Sheep Infected with Fasciola hepaticaPhosphorylation site dynamics of early T-cell receptor signalingThe Structural Basis for Activation and Inhibition of ZAP-70 Kinase DomainAutoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate.Non-degradative Ubiquitination of Protein Kinases.A large Rab GTPase encoded by CRACR2A is a component of subsynaptic vesicles that transmit T cell activation signals.Actin polymerization-dependent activation of Cas-L promotes immunological synapse stabilitySelective Targeting of SH2 Domain-Phosphotyrosine Interactions of Src Family Tyrosine Kinases with Monobodies.Molecular mechanisms underlying the evolution of the slp76 signalosome.Novel tools to dissect the dynamic regulation of TCR signaling by the kinase Csk and the phosphatase CD45A cycle of Zap70 kinase activation and release from the TCR amplifies and disperses antigenic stimuli.Quantitative analysis of protein phosphorylations and interactions by multi-colour IP-FCM as an input for kinetic modelling of signalling networksGene expression profiling of peripheral blood cells: new insights into Ewing sarcoma biology and clinical applications.A sharp T-cell antigen receptor signaling threshold for T-cell proliferation.Protein clusters on the T cell surface may suppress spurious early signaling events.The human CD8β M-4 isoform dominant in effector memory T cells has distinct cytoplasmic motifs that confer unique properties.Dynamic motile T cells highly respond to the T cell stimulation via PI3K-Akt and NF-κB pathways.Sts-2 is a phosphatase that negatively regulates zeta-associated protein (ZAP)-70 and T cell receptor signaling pathwaysComputational approach to identify enzymes that are potential therapeutic candidates for psoriasis.The Bordetella pertussis adenylate cyclase toxin binds to T cells via LFA-1 and induces its disengagement from the immune synapseRelative extended haplotype homozygosity signals across breeds reveal dairy and beef specific signatures of selection.The coreceptor CD4 is expressed in distinct nanoclusters and does not colocalize with T-cell receptor and active protein tyrosine kinase p56lckModification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding.Regulatory T cells require TCR signaling for their suppressive functionRegulation of T cell development by c-Cbl: essential role of Lck.Functional nanoscale organization of signaling molecules downstream of the T cell antigen receptor.Immunoreceptor signalingInvolvement of soluble scavenger receptor A in suppression of T cell activation in patients with chronic hepatitis B.The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway.Aberrant T-lymphocyte development and function in mice overexpressing human soluble amyloid precursor protein-α: implications for autism.A CRISPR-Based Toolbox for Studying T Cell Signal Transduction.Molecular basis for T cell response induced by altered peptide ligand of type II collagen.The Ebola Interferon Inhibiting Domains Attenuate and Dysregulate Cell-Mediated Immune Responses.
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description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 2010
@en
vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
ZAP-70: an essential kinase in T-cell signaling
@en
ZAP-70: an essential kinase in T-cell signaling.
@nl
type
label
ZAP-70: an essential kinase in T-cell signaling
@en
ZAP-70: an essential kinase in T-cell signaling.
@nl
prefLabel
ZAP-70: an essential kinase in T-cell signaling
@en
ZAP-70: an essential kinase in T-cell signaling.
@nl
P2093
P2860
P50
P1476
ZAP-70: an essential kinase in T-cell signaling
@en
P2093
Hanna E Sjölin Goodfellow
Haopeng Wang
Lih-Yun Hsu
P2860
P304
P356
10.1101/CSHPERSPECT.A002279
P577
2010-05-01T00:00:00Z