Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses.
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Membrane progesterone receptors: evidence for neuroprotective, neurosteroid signaling and neuroendocrine functions in neuronal cellsEvolving concepts in cancer therapy through targeting sphingolipid metabolismIntercellular transport of microRNAsNeutral sphingomyelinase and breast cancer researchRoles and regulation of neutral sphingomyelinase-2 in cellular and pathological processesIdentification and biochemical characterization of an acid sphingomyelinase-like protein from the bacterial plant pathogen Ralstonia solanacearum that hydrolyzes ATP to AMP but not sphingomyelin to ceramideEarly activation of nSMase2/ceramide pathway in astrocytes is involved in ischemia-associated neuronal damage via inflammation in rat hippocampiPrimary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide.Neutral sphingomyelinase-3 mediates TNF-stimulated oxidant activity in skeletal muscleLung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor.Expression profiles of podocytes exposed to high glucose reveal new insights into early diabetic glomerulopathyLithocholic acid disrupts phospholipid and sphingolipid homeostasis leading to cholestasis in mice.Tetanus Toxin Hc Fragment Induces the Formation of Ceramide Platforms and Protects Neuronal Cells against Oxidative Stress.The neutral sphingomyelinase pathway regulates packaging of the prion protein into exosomes.Neutral sphingomyelinase-2 mediates growth arrest by retinoic acid through modulation of ribosomal S6 kinaseCholine metabolism in malignant transformation.A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization.Lung cancer and lung injury: the dual role of ceramideSphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics.Neutral sphingomyelinase 2 activity and protein stability are modulated by phosphorylation of five conserved serines.Neutral sphingomyelinase-2 is a redox sensitive enzyme: role of catalytic cysteine residues in regulation of enzymatic activity through changes in oligomeric state.Evidence for coordination of lysosomal (ASMase) and plasma membrane (NSMase2) forms of sphingomyelinase from mutant mice.Fatty acid synthase causes drug resistance by inhibiting TNF-α and ceramide productionIncreased ceramide in brains with Alzheimer's and other neurodegenerative diseasesATRA transcriptionally induces nSMase2 through CBP/p300-mediated histone acetylation.Toxoplasma gondii salvages sphingolipids from the host Golgi through the rerouting of selected Rab vesicles to the parasitophorous vacuole.Off-target function of the Sonic hedgehog inhibitor cyclopamine in mediating apoptosis via nitric oxide-dependent neutral sphingomyelinase 2/ceramide inductionNeutral sphingomyelinase 2 (nSMase2) is the primary neutral sphingomyelinase isoform activated by tumour necrosis factor-α in MCF-7 cells.Biological functionalization of drug delivery carriers to bypass size restrictions of receptor-mediated endocytosis independently from receptor targeting.Novel chemotherapeutic drugs in sphingolipid cancer research.The neutral sphingomyelinase family: identifying biochemical connections.Drug targeting of sphingolipid metabolism: sphingomyelinases and ceramidases.The roles of neutral sphingomyelinases in neurological pathologies.Lipid-based carriers of microRNAs and intercellular communication.Anti-apoptotic and anti-oxidative mechanisms of minocycline against sphingomyelinase/ceramide neurotoxicity: implication in Alzheimer's disease and cerebral ischemia.Sphingolipid metabolism and neutral sphingomyelinases.Sphingomyelin Phosphodiesterase 3 Enhances Cytodifferentiation of Periodontal Ligament Cells.Identification and characterization of Laodelphax striatellus (Insecta: Hemiptera: Delphacidae) neutral sphingomyelinase.Biogenesis and Functions of Exosomes and Extracellular Vesicles.Inhibition of neutral sphingomyelinase decreases elevated levels of nitrative and oxidative stress markers in liver ischemia-reperfusion injury.
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Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 16 June 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses.
@en
Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses.
@nl
type
label
Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses.
@en
Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses.
@nl
prefLabel
Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses.
@en
Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses.
@nl
P2860
P1476
Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses.
@en
P2093
Christopher J Clarke
P2860
P2888
P304
P356
10.1007/S12017-010-8120-Z
P577
2010-06-16T00:00:00Z