Understanding the structure and function of the immunological synapse
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Mechanisms behind functional avidity maturation in T cellsβ-Arrestin-1 mediates the TCR-triggered re-routing of distal receptors to the immunological synapse by a PKC-mediated mechanismA motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28Autoimmune therapies targeting costimulation and emerging trends in multivalent therapeuticsNeuroendocrine regulation of inflammationImpaired T-Cell Function in B-Cell Lymphoma: A Direct Consequence of Events at the Immunological Synapse?Controversy and consensus regarding myosin II function at the immunological synapseMolecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapseMast cells and dendritic cells form synapses that facilitate antigen transfer for T cell activation.Diacylglycerol Kinases: Shaping Diacylglycerol and Phosphatidic Acid Gradients to Control Cell PolarityMechanism and function of Vav1 localisation in TCR signalling.Body-barrier surveillance by epidermal γδ TCRs.Characterization of dynamic actin associations with T-cell receptor microclusters in primary T cells.HIV-1 Gag, Envelope, and Extracellular Determinants Cooperate To Regulate the Stability and Turnover of Virological Synapses.Using Murine Models to Investigate Tumor-Lymphoid Interactions: Spotlight on Chronic Lymphocytic Leukemia and Angioimmunoblastic T-Cell Lymphoma.Myristoylation: An Important Protein Modification in the Immune ResponseNew insights into the role of EMT in tumor immune escape.Cell distance mapping identifies functional T follicular helper cells in inflamed human renal tissue.The CD3-zeta chimeric antigen receptor overcomes TCR Hypo-responsiveness of human terminal late-stage T cells.HIV-1 Nef: a multifaceted modulator of T cell receptor signaling.Towards efficient cancer immunotherapy: advances in developing artificial antigen-presenting cells.Non-catalytic functions of Pyk2 and Fyn regulate late stage adhesion in human T cells.Phase transitions of multivalent proteins can promote clustering of membrane receptorsIn TCR-stimulated T-cells, N-ras regulates specific genes and signal transduction pathwaysThe variable hinge region of novel PKCs determines localization to distinct regions of the immunological synapseLymphocyte polarity, the immunological synapse and the scope of biological analogy.The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway.Deletion of IFT20 in early stage T lymphocyte differentiation inhibits the development of collagen-induced arthritis.High throughput method to quantify anterior-posterior polarity of T-cells and epithelial cells.The differential production of cytokines by human Langerhans cells and dermal CD14(+) DCs controls CTL primingFrom lipid second messengers to molecular motors: microtubule-organizing center reorientation in T cellsAssociation with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex.Quantitative phosphoproteomic analysis reveals a role for serine and threonine kinases in the cytoskeletal reorganization in early T cell receptor activation in human primary T cells.The linker for activation of T cells (LAT) signaling hub: from signaling complexes to microclustersBidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.Nitrosothiols in the immune system: signaling and protection.Functional single-cell analysis of T-cell activation by supported lipid bilayer-tethered ligands on arrays of nanowells.The emerging role of protein kinase Cθ in cytoskeletal signaling.Cytotoxic T Cells Use Mechanical Force to Potentiate Target Cell KillingIn and out of the bull's eye: protein kinase Cs in the immunological synapse.
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Understanding the structure and function of the immunological synapse
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 15 September 2010
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Understanding the structure and function of the immunological synapse
@en
Understanding the structure and function of the immunological synapse.
@nl
type
label
Understanding the structure and function of the immunological synapse
@en
Understanding the structure and function of the immunological synapse.
@nl
prefLabel
Understanding the structure and function of the immunological synapse
@en
Understanding the structure and function of the immunological synapse.
@nl
P2860
P1476
Understanding the structure and function of the immunological synapse
@en
P2093
Andrey S Shaw
Arup K Chakraborty
P2860
P304
P356
10.1101/CSHPERSPECT.A002311
P577
2010-09-15T00:00:00Z