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Biological influence of Hakai in cancer: a 10-year reviewNitric oxide and pH modulation in gynaecological cancerSLC transporters as a novel class of tumour suppressors: identity, function and molecular mechanismsIs carbonic anhydrase IX a validated target for molecular imaging of cancer and hypoxia?Recent developments in targeting carbonic anhydrase IX for cancer therapeuticsIntracellular cAMP signaling by soluble adenylyl cyclase.The bZIP transcription factor Rca1p is a central regulator of a novel CO₂ sensing pathway in yeast.Molecular mechanisms of ischemic preconditioning in the kidneyTM9SF4 is a novel V-ATPase-interacting protein that modulates tumor pH alterations associated with drug resistance and invasiveness of colon cancer cellsIn vivo pH in metabolic-defective Ras-transformed fibroblast tumors: key role of the monocarboxylate transporter, MCT4, for inducing an alkaline intracellular pH.Hypoxia-induced invadopodia formation involves activation of NHE-1 by the p90 ribosomal S6 kinase (p90RSK).Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer questionHuman voltage-gated proton channel hv1: a new potential biomarker for diagnosis and prognosis of colorectal cancer.Human Plasma Very Low-Density Lipoproteins Are Stabilized by Electrostatic Interactions and Destabilized by Acidic pHIdentification of metal dithiocarbamates as a novel class of antileishmanial agentsIdentification of key binding site residues of MCT1 for AR-C155858 reveals the molecular basis of its isoform selectivity.ZEB1 transcriptionally regulated carbonic anhydrase 9 mediates the chemoresistance of tongue cancer via maintaining intracellular pH.Understanding nucleus pulposus cell phenotype: a prerequisite for stem cell based therapies to treat intervertebral disc degenerationRenal cancer: oxygen meets metabolismAlteration of ASIC1 expression in clear cell renal cell carcinoma.Hypoxia-induced carbonic anhydrase IX facilitates lactate flux in human breast cancer cells by non-catalytic function.Acidosis promotes Bcl-2 family-mediated evasion of apoptosis: involvement of acid-sensing G protein-coupled receptor Gpr65 signaling to Mek/Erk.pH, Lactate, and Hypoxia: Reciprocity in Regulating High-Affinity Monocarboxylate Transporter Expression in GlioblastomaAcetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastomaMicrotargeting cancer metabolism: opening new therapeutic windows based on lipid metabolismKnock-down of hypoxia-induced carbonic anhydrases IX and XII radiosensitizes tumor cells by increasing intracellular acidosisCation-coupled bicarbonate transportersCombination of lactate calcium salt with 5-indanesulfonamide and α-cyano-4-hydroxycinnamic acid to enhance the antitumor effect on HCT116 cells via intracellular acidificationNuclear receptors and the Warburg effect in cancer.Genetic basis for the increased expression of vacuolar H+ translocating ATPase genes upon imatinib treatment in human lymphoblastoid cells.The endothelial lipase protein is promising urinary biomarker for diagnosis of gastric cancer.Decreased extracellular pH inhibits osteogenesis through proton-sensing GPR4-mediated suppression of yes-associated proteinRoles of acid-extruding ion transporters in regulation of breast cancer cell growth in a 3-dimensional microenvironment.Carbonic anhydrase IX from cancer-associated fibroblasts drives epithelial-mesenchymal transition in prostate carcinoma cells.Spearhead Nanometric Field-Effect Transistor Sensors for Single-Cell Analysis.The gut in iron homeostasis: role of HIF-2 under normal and pathological conditionsMatriptase activation and shedding through PDGF-D-mediated extracellular acidosis.Lactate/pyruvate transporter MCT-1 is a direct Wnt target that confers sensitivity to 3-bromopyruvate in colon cancer.Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs--an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research.Single-cell intracellular nano-pH probes.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on February 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
pH control mechanisms of tumor survival and growth.
@en
pH control mechanisms of tumor survival and growth.
@nl
type
label
pH control mechanisms of tumor survival and growth.
@en
pH control mechanisms of tumor survival and growth.
@nl
prefLabel
pH control mechanisms of tumor survival and growth.
@en
pH control mechanisms of tumor survival and growth.
@nl
P356
P1476
pH control mechanisms of tumor survival and growth.
@en
P2093
Johanna Chiche
Scott K Parks
P304
P356
10.1002/JCP.22400
P577
2011-02-01T00:00:00Z