The FERM domain: organizing the structure and function of FAK.
about
Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African AmericansProteins interacting with cloning scars: a source of false positive protein-protein interactionsFAK promotes recruitment of talin to nascent adhesions to control cell motilityGelatinase B/MMP-9 in Tumour Pathogenesis and ProgressionEvolution of SH2 domains and phosphotyrosine signalling networksMechanosensitivity and compositional dynamics of cell-matrix adhesionsNuclear FAK: a new mode of gene regulation from cellular adhesionsFAK in cancer: mechanistic findings and clinical applicationsNovel Phosphotidylinositol 4,5-Bisphosphate Binding Sites on Focal Adhesion KinaseThe FAK-Arp2/3 interaction promotes leading edge advance and haptosensing by coupling nascent adhesions to lamellipodia actin.FAK acts as a suppressor of RTK-MAP kinase signalling in Drosophila melanogaster epithelia and human cancer cellsThe proteomic landscape of triple-negative breast cancer.Structural Basis for Small G Protein Effector Interaction of Ras-related Protein 1 (Rap1) and Adaptor Protein Krev Interaction Trapped 1 (KRIT1)FAK dimerization controls its kinase-dependent functions at focal adhesionsPhosphatidylinositol 4,5-bisphosphate triggers activation of focal adhesion kinase by inducing clustering and conformational changesThe Mammalian Blood-Testis Barrier: Its Biology and RegulationEmerging methodologies to investigate lipid-protein interactionsThe blood-testis barrier and its implications for male contraceptionQuantitative proteomic profiling identifies DPYSL3 as pancreatic ductal adenocarcinoma-associated molecule that regulates cell adhesion and migration by stabilization of focal adhesion complexStructural analysis of the KRIT1 ankyrin repeat and FERM domains reveals a conformationally stable ARD-FERM interfaceKindlin-2 tyrosine phosphorylation and interaction with Src serve as a regulatable switch in the integrin outside-in signaling circuit.Signaling networks that regulate cell migrationβ₁Integrin/FAK/cortactin signaling is essential for human head and neck cancer resistance to radiotherapyThe Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins.The regulation of focal adhesion complex formation and salivary gland epithelial cell organization by nanofibrous PLGA scaffolds.Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells.Inhibiting the interaction of cMET and IGF-1R with FAK effectively reduces growth of pancreatic cancer cells in vitro and in vivoHGF/Met Signaling in Cancer Invasion: The Impact on Cytoskeleton Remodeling.Integrin α2β1 in nonactivated conformation can induce focal adhesion kinase signalingTetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cellsFunctions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.FRAS1 knockdown reduces A549 cells migration and invasion through downregulation of FAK signaling.Targeting the C-terminal focal adhesion kinase scaffold in pancreatic cancerPaired immunoglobulin-like receptor B regulates platelet activation.Activation of endogenous FAK via expression of its amino terminal domain in Xenopus embryosHigh focal adhesion kinase expression in breast carcinoma is associated with lymphovascular invasion and triple-negative phenotype.Nuclear FAK controls chemokine transcription, Tregs, and evasion of anti-tumor immunity.Enhanced apoptotic effects by the combination of curcumin and methylseleninic acid: potential role of Mcl-1 and FAK.Disruption of focal adhesion kinase and p53 interaction with small molecule compound R2 reactivated p53 and blocked tumor growth.Understanding the roles of FAK in cancer: inhibitors, genetic models, and new insights
P2860
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P2860
The FERM domain: organizing the structure and function of FAK.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
The FERM domain: organizing the structure and function of FAK.
@en
The FERM domain: organizing the structure and function of FAK.
@nl
type
label
The FERM domain: organizing the structure and function of FAK.
@en
The FERM domain: organizing the structure and function of FAK.
@nl
prefLabel
The FERM domain: organizing the structure and function of FAK.
@en
The FERM domain: organizing the structure and function of FAK.
@nl
P2093
P356
P1476
The FERM domain: organizing the structure and function of FAK.
@en
P2093
Bryan Serrels
Hitesh Patel
Michael J Eck
P2888
P304
P356
10.1038/NRM2996
P577
2010-11-01T00:00:00Z
P5875
P6179
1026995058