Enigmatic MYC Conducts an Unfolding Systems Biology Symphony.
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c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cellsN-Myc and L-Myc are essential for hair cell formation but not maintenanceStress-induced cleavage of Myc promotes cancer cell survivalKinetic profiling of the c-Myc transcriptome and bioinformatic analysis of repressed gene promoters.Demonstration that drug-targeted down-regulation of MYC in non-Hodgkins lymphoma is directly mediated through the promoter G-quadruplex.Proteomic profiling of high risk medulloblastoma reveals functional biologyMYCN amplification confers enhanced folate dependence and methotrexate sensitivity in neuroblastoma.The soy isoflavone equol may increase cancer malignancy via up-regulation of eukaryotic protein synthesis initiation factor eIF4GER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth.Prognostic PET 18F-FDG uptake imaging features are associated with major oncogenomic alterations in patients with resected non-small cell lung cancerPartition of Myc into immobile vs. mobile complexes within nuclei.Metabolic host responses to infection by intracellular bacterial pathogensMYC degradation under low O2 tension promotes survival by evading hypoxia-induced cell death.Impact of c-MYC protein expression on outcome of patients with early-stage HER2+ breast cancer treated with adjuvant trastuzumab NCCTG (alliance) N9831.Cellular MYCro economics: Balancing MYC function with MYC expression.Nucleic acid clamp-mediated recognition and stabilization of the physiologically relevant MYC promoter G-quadruplex.Targeting RNA polymerase I to treat MYC-driven cancer.MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis.Wedelolactone, an Anti-inflammatory Botanical, Interrupts c-Myc Oncogenic Signaling and Synergizes with Enzalutamide to Induce Apoptosis in Prostate Cancer Cells.Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer.PET Radiomics in NSCLC: state of the art and a proposal for harmonization of methodology.Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models.Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 binding.Myc, Max, and Mnt: molecular mechanisms of enhancement of cholangiocarcinogenesis by cholestasis.L-Proline uptake in Saccharomyces cerevisiae mitochondria can contribute to bioenergetics during nutrient stress as alternative mitochondrial fuel.RAFT Polymerization for the Synthesis of Tertiary Amine-Based Diblock Copolymer Nucleic Acid Delivery Vehicles.MicroRNA-27a-5p regulation by promoter methylation and MYC signaling in prostate carcinogenesis.
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Enigmatic MYC Conducts an Unfolding Systems Biology Symphony.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on June 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Enigmatic MYC Conducts an Unfolding Systems Biology Symphony.
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Enigmatic MYC Conducts an Unfolding Systems Biology Symphony.
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type
label
Enigmatic MYC Conducts an Unfolding Systems Biology Symphony.
@en
Enigmatic MYC Conducts an Unfolding Systems Biology Symphony.
@nl
prefLabel
Enigmatic MYC Conducts an Unfolding Systems Biology Symphony.
@en
Enigmatic MYC Conducts an Unfolding Systems Biology Symphony.
@nl
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Enigmatic MYC Conducts an Unfolding Systems Biology Symphony
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P2093
Chi V Dang
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P304
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10.1177/1947601910378742
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P577
2010-06-01T00:00:00Z