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Salinomycin as a drug for targeting human cancer stem cellsDiabetes and cancer: two diseases with obesity as a common risk factorMetformin therapy and risk of cancer in patients with type 2 diabetes: systematic reviewResponse of breast cancer cells and cancer stem cells to metformin and hyperthermia alone or combinedEffect of metformin on cancer risk and treatment outcome of prostate cancer: a meta-analysis of epidemiological observational studiesAdenosine Monophosphate-activated Protein Kinase (AMPK) Activators For the Prevention, Treatment and Potential Reversal of Pathological Pain.Cancer stem cells: a systems biology view of their role in prognosis and therapyNew frontiers in the treatment of colorectal cancer: Autophagy and the unfolded protein response as promising targetsMetformin reduces thyroid cancer risk in Taiwanese patients with type 2 diabetes.Metformin in cancer prevention and therapy.Lovastatin induces multiple stress pathways including LKB1/AMPK activation that regulate its cytotoxic effects in squamous cell carcinoma cells.Activation of the cellular unfolded protein response by recombinant adeno-associated virus vectors.Metformin use among type 2 diabetics and risk of pancreatic cancer in a clinic-based case-control studyMetformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion currentMetformin induces apoptosis through AMPK-dependent inhibition of UPR signaling in ALL lymphoblasts.Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumorsEffect of Metformin on Viability, Morphology, and Ultrastructure of Mouse Bone Marrow-Derived Multipotent Mesenchymal Stromal Cells and Balb/3T3 Embryonic Fibroblast Cell Line.Investigational cancer drugs targeting cell metabolism in clinical development.Mortality after incident cancer in people with and without type 2 diabetes: impact of metformin on survivalMetformin kills and radiosensitizes cancer cells and preferentially kills cancer stem cellsMetformin suppresses growth of human head and neck squamous cell carcinoma via global inhibition of protein translation.Metformin: an emerging new therapeutic option for targeting cancer stem cells and metastasisA novel inverse relationship between metformin-triggered AMPK-SIRT1 signaling and p53 protein abundance in high glucose-exposed HepG2 cells.Metformin use and the risk of colorectal adenoma: A systematic review and meta-analysis.Metformin inhibits early stage diethylnitrosamine‑induced hepatocarcinogenesis in rats.Metformin inhibits leptin-induced growth and migration of glioblastoma cells.The use of metformin and the incidence of lung cancer in patients with type 2 diabetes.Metformin for cancer and aging prevention: is it a time to make the long story short?Tristetraprolin mediates the anti-proliferative effects of metformin in breast cancer cellsMetformin may reduce oral cancer risk in patients with type 2 diabetesThe impact of metformin and salinomycin on transforming growth factor β-induced epithelial-to-mesenchymal transition in non-small cell lung cancer cell linesMetformin Decreases Reactive Oxygen Species, Enhances Osteogenic Properties of Adipose-Derived Multipotent Mesenchymal Stem Cells In Vitro, and Increases Bone Density In VivoConstruction of In Vivo Fluorescent Imaging of Echinococcus granulosus in a Mouse Model.Role of the ROS/AMPK signaling pathway in tetramethylpyrazine-induced apoptosis in gastric cancer cellsMetformin, at concentrations corresponding to the treatment of diabetes, potentiates the cytotoxic effects of carboplatin in cultures of ovarian cancer cellsMetformin sensitizes the response of oral squamous cell carcinoma to cisplatin treatment through inhibition of NF-κB/HIF-1α signal axis.Bioavailable copper modulates oxidative phosphorylation and growth of tumors.AMP-activated protein kinase fortifies epithelial tight junctions during energetic stress via its effector GIV/Girdin.Enhanced anti-tumor activity and cytotoxic effect on cancer stem cell population of metformin-butyrate compared with metformin HCl in breast cancer.
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description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 08 February 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Metformin and cancer: new applications for an old drug.
@en
Metformin and cancer: new applications for an old drug.
@nl
type
label
Metformin and cancer: new applications for an old drug.
@en
Metformin and cancer: new applications for an old drug.
@nl
prefLabel
Metformin and cancer: new applications for an old drug.
@en
Metformin and cancer: new applications for an old drug.
@nl
P2860
P1433
P1476
Metformin and cancer: new applications for an old drug.
@en
P2093
Robert D Siegel
Taxiarchis V Kourelis
P2860
P2888
P304
P356
10.1007/S12032-011-9846-7
P577
2011-02-08T00:00:00Z