about
Serelaxin for the treatment of acute heart failure: a review with a focus on end-organ protectionG-Protein-coupled receptors as potential drug candidates in preeclampsia: targeting the relaxin/insulin-like family peptide receptor 1 for treatment and preventionIn a Class of Their Own - RXFP1 and RXFP2 are Unique Members of the LGR FamilyRole of the Extracellular and Intracellular Loops of Follicle-Stimulating Hormone Receptor in Its FunctionThe effect of relaxin on the musculoskeletal systemCardiac endothelium-myocyte interaction: clinical opportunities for new heart failure therapies regardless of ejection fractionPhysiological effects and therapeutic potential of proinsulin C-peptideRelaxin protects rat lungs from ischemia-reperfusion injury via inducible NO synthase: role of ERK-1/2, PI3K, and forkhead transcription factor FKHRL1Growth Coordination During Drosophila melanogaster Imaginal Disc Regeneration Is Mediated by Signaling Through the Relaxin Receptor Lgr3 in the Prothoracic Gland.The relaxin receptor (RXFP1) utilizes hydrophobic moieties on a signaling surface of its N-terminal low density lipoprotein class A module to mediate receptor activation.The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptorsSynthesis of fluorescent analogs of relaxin family peptides and their preliminary in vitro and in vivo characterization.Treatment for cerebral small vessel disease: effect of relaxin on the function and structure of cerebral parenchymal arterioles during hypertensionSerelaxin treatment promotes adaptive hypertrophy but does not prevent heart failure in experimental peripartum cardiomyopathy.Role of sphingosine kinase/S1P axis in ECM remodeling of cardiac cells elicited by relaxinSphingosine 1-Phosphate Receptors: Do They Have a Therapeutic Potential in Cardiac Fibrosis?ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.Diverse cell type-specific mechanisms localize G protein-coupled receptors to Caenorhabditis elegans sensory ciliaDevelopment of a selective agonist for relaxin family peptide receptor 3.Distinct activation modes of the Relaxin Family Peptide Receptor 2 in response to insulin-like peptide 3 and relaxinCharacterizing the reproductive transcriptomic correlates of acute dehydration in males in the desert-adapted rodent, Peromyscus eremicus.Serelaxin in addition to standard therapy in acute heart failure: rationale and design of the RELAX-AHF-2 study.Multi-tissue omics analyses reveal molecular regulatory networks for puberty in composite beef cattleSerelaxin: a novel therapy for acute heart failure with a range of hemodynamic and non-hemodynamic actionsUpregulation of relaxin after experimental subarachnoid hemorrhage in rabbitsInvestigation of interactions at the extracellular loops of the relaxin family peptide receptor 1 (RXFP1).Serelaxin reduces oxidative stress and asymmetric dimethylarginine in angiotensin II-induced hypertension.Identification and optimization of small-molecule agonists of the human relaxin hormone receptor RXFP1.Relaxin activates peroxisome proliferator-activated receptor γ (PPARγ) through a pathway involving PPARγ coactivator 1α (PGC1α)Trastuzumab alters the expression of genes essential for cardiac function and induces ultrastructural changes of cardiomyocytes in mice.Synthetic covalently linked dimeric form of H2 relaxin retains native RXFP1 activity and has improved in vitro serum stability.Relaxin does not improve Angiotensin II-induced target-organ damage.International Union of Basic and Clinical Pharmacology. XCV. Recent advances in the understanding of the pharmacology and biological roles of relaxin family peptide receptors 1-4, the receptors for relaxin family peptides.Zearalenone mycotoxin affects immune mediators, MAPK signalling molecules, nuclear receptors and genome-wide gene expression in pig spleen.Profiling of relaxin and its receptor proteins in boar reproductive tissues and spermatozoa.Pregnancy complications and birth outcomes among women experiencing nausea only or nausea and vomiting during pregnancy in the Norwegian Mother and Child Cohort Study.Increase of cortical cerebral blood flow and further cerebral microcirculatory effects of Serelaxin in a sheep model.Recombinant human relaxin versus placebo for cervical ripening: a double-blind randomised trial in pregnant women scheduled for induction of labourDilp8 requires the neuronal relaxin receptor Lgr3 to couple growth to developmental timingConditional deletion of the relaxin receptor gene in cells of smooth muscle lineage affects lower reproductive tract in pregnant mice.
P2860
Q26740185-6D889DF6-94AA-4E91-9435-D9EBB1BBD4ABQ26744192-7569E88D-5B31-4C5F-802E-23777A9ABFEEQ26781446-EE2C8763-42AD-4BBD-80AD-64485936D88CQ26800024-55DC13B2-E463-4CC3-B32D-3C45AB497F46Q26828539-7F447506-970C-4E48-86F6-3169672088F0Q26853363-F19D00AC-E4FA-4B84-903E-3B99C5BF4F7DQ27012286-B0298ACD-1BBD-4342-ACE7-3B01EDF40FEAQ28533941-0CCBC95E-C216-46B0-8CAB-A8A304173FAAQ30276070-50DFBFD3-0CF4-4C63-9632-45FAF5F97877Q30352669-43835ECE-B802-4851-96F6-79CF83357ECEQ30486707-501959A4-8F4B-4A81-8A7D-5242E0861919Q30575864-9C1CCA57-F8E3-40D8-B55A-08B220D5EFD3Q30579950-F658E540-79E2-4951-8292-3C28FFFBF512Q33623465-6CF0A93D-D804-463B-965E-059B505B5694Q33631848-7A8E548B-206A-401D-B931-5A695602334BQ33753317-F1C57518-2711-4BF3-A43E-9D9A5917380FQ33774441-D5BD701B-BFCB-45BB-8A42-A3BF300B4088Q33779611-7E38B088-2271-45DB-B4A5-642E39827FDEQ33789534-D71B736C-BF21-4BAE-B60C-09D8AE96804FQ33789816-287CE2CE-7C96-4F69-9389-35BF3E707FF6Q33827451-FC2C07A6-2867-4D73-923F-0412E0553ED3Q33845755-14966204-089F-4DE7-8B96-3670402A069FQ33928212-98B6F3CE-DA52-47D8-998A-304941D0E1D1Q33970136-F3EE181D-ED44-4D55-A0DC-7B2D0447BFC5Q34009712-90278B92-74AD-49F4-97A1-2C7CBAF87DE2Q34683416-D5E75160-9B66-4915-B824-785FF0CD0C73Q34726868-9833DEDF-2EC3-4552-B53B-1DEB7811E1EDQ34771756-1EECB7E0-B490-4423-9BCB-D3ED266A6197Q34958919-EF8D9774-6A85-4530-8FE1-64559751BE4AQ35047415-4D6F5CBE-7BAC-4369-875B-C71988E5F234Q35050690-8C5E19F4-9DD4-468F-BB9F-6784829D94B6Q35141812-CBB554EC-D2F1-40B5-A8D9-40D4AC713DB0Q35383835-1883886D-25C1-426D-A6EA-7D1F2BF30B72Q35642170-16FAFFCC-B356-4DD0-BBFE-C0B20C103E2CQ35653980-C44C2C34-001A-4281-AF5F-4E5B6EC85939Q35671229-9EC452B6-FCA6-48A8-880D-EE387E87DD24Q36073516-6568FECB-5B32-4666-8990-0378ADEC7BAAQ36123438-81A08F20-C78F-443D-9AE7-77A84800D241Q36266787-5C506C5D-79A9-4CEA-AD8D-0F4BD5FC4893Q36277282-24C78C28-E5DB-4B89-B861-A4496F22FE5C
P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Relaxin family peptides and their receptors.
@en
type
label
Relaxin family peptides and their receptors.
@en
prefLabel
Relaxin family peptides and their receptors.
@en
P2093
P1476
Relaxin family peptides and their receptors.
@en
P2093
E T van der Westhuizen
G E Callander
R J Summers
P304
P356
10.1152/PHYSREV.00001.2012
P577
2013-01-01T00:00:00Z