Small molecules as pro-apoptotic anticancer agents.

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Discovery of small molecule inhibitors for the C. elegans caspase CED-3 by high-throughput screening.Peptide aptamer identified by molecular docking targeting translationally controlled tumor protein in leukemia cells.

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Small molecules as pro-apoptotic anticancer agents.

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http://www.wikidata.org/entity/Q38162939

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article científic

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article scientifique

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articolo scientifico

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Small molecules as pro-apoptotic anticancer agents.

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Small molecules as pro-apoptotic anticancer agents.

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Small molecules as pro-apoptotic anticancer agents.

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Small molecules as pro-apoptotic anticancer agents.

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Pierfausto Seneci

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Structural basis for the inhibition of caspase-3 by XIAP

p53 has a direct apoptogenic role at the mitochondria

Mdm2 promotes the rapid degradation of p53

Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

Small-molecule inhibitors of the MDM2-p53 protein-protein interaction to reactivate p53 function: a novel approach for cancer therapy

Targeting Mcl-1 for the therapy of cancer

Structural and biochemical basis of apoptotic activation by Smac/DIABLO

Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain

Discovery of a Potent Small-Molecule Antagonist of Inhibitor of Apoptosis (IAP) Proteins and Clinical Candidate for the Treatment of Cancer (GDC-0152)

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483-505

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scholarly article

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10.4155/PPA.12.41

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http://www.w3.org/2001/XMLSchema#string

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2012-09-01T00:00:00Z

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24236885

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apoptotic process

Small molecules as pro-apoptotic anticancer agents.

about

P2860

P2860

Small molecules as pro-apoptotic anticancer agents.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P921

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P921