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Molecular Pathways Bridging Frontotemporal Lobar Degeneration and Psychiatric DisordersThe role of progranulin in diabetes and kidney diseaseUsing the social amoeba Dictyostelium to study the functions of proteins linked to neuronal ceroid lipofuscinosisFrontotemporal Dementia.A Review of Gaucher Disease Pathophysiology, Clinical Presentation and TreatmentsProgranulin deficiency causes the retinal ganglion cell loss during development.Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia.Decreased progranulin levels in patients and rats with subarachnoid hemorrhage: a potential role in inhibiting inflammation by suppressing neutrophil recruitment.Progranulin and Its Related MicroRNAs after Status Epilepticus: Possible Mechanisms of Neuroprotection.Progranulin inhibits expression and release of chemokines CXCL9 and CXCL10 in a TNFR1 dependent mannerProgranulin promotes the retinal precursor cell proliferation and the photoreceptor differentiation in the mouse retina.Signaling Pathway of GP88 (Progranulin) in Breast Cancer Cells: Upregulation and Phosphorylation of c-myc by GP88/Progranulin in Her2-Overexpressing Breast Cancer CellsProgranulin Levels in Plasma and Cerebrospinal Fluid in Granulin Mutation Carriers.Lack of estrogen receptor α in astrocytes of progranulin-deficient mice.Progranulin Recruits HSP70 to β-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease.The established and emerging roles of astrocytes and microglia in amyotrophic lateral sclerosis and frontotemporal dementiaThe Receptor-interacting Serine/Threonine Protein Kinase 1 (RIPK1) Regulates Progranulin Levels.Induced pluripotent stem cell-based modeling of neurodegenerative diseases: a focus on autophagy.Genetics of FTLD: overview and what else we can expect from genetic studies.Progranulin functions as a cathepsin D chaperone to stimulate axonal outgrowth in vivo.Genetics of Frontotemporal Lobar Degeneration: From the Bench to the Clinic.Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network.Molecular Genetics of Neurodegenerative Dementias.Microglia and C9orf72 in neuroinflammation and ALS and frontotemporal dementia.Reduced Tau protein expression is associated with frontotemporal degeneration with progranulin mutation.Angiogenin Prevents Progranulin A9D Mutation-Induced Neuronal-Like Cell Apoptosis Through Cleaving tRNAs into tiRNAs.Stability of Progranulin Under Pre-Analytical Conditions in Serum and Cerebrospinal Fluid.A novel frameshift GRN mutation results in frontotemporal lobar degeneration with a distinct clinical phenotype in two siblings: case report and literature review.Progranulin as a Novel Factor in Gaucher Disease.Progranulin and the receptor tyrosine kinase EphA2, partners in crime?The Progranulin Cleavage Products, Granulins, Exacerbate TDP-43 Toxicity and Increase TDP-43 Levels.Disease and Region Specificity of Granulin Immunopositivities in Alzheimer Disease and Frontotemporal Lobar Degeneration.Another piece in the progranulin puzzle: special binding between progranulin and prosaposin creates additional lysosomal access: An Editorial Comment for 'The interaction between progranulin and prosaposin is mediated by granulins and the linker regProgranulin and its biological effects in cancer.Loss of TMEM106B Ameliorates Lysosomal and Frontotemporal Dementia-Related Phenotypes in Progranulin-Deficient Mice.Progranulin-mediated deficiency of cathepsin D results in FTD and NCL-like phenotypes in neurons derived from FTD patients.Foxo4- and Stat3-dependent IL-10 production by progranulin in regulatory T cells restrains inflammatory arthritis.Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay.Peripheral nerve atrophy together with higher cerebrospinal fluid progranulin indicate axonal damage in amyotrophic lateral sclerosis.Progranulin serum levels in human kidney transplant recipients: A longitudinal study.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Progranulin in neurodegenerative disease.
@en
type
label
Progranulin in neurodegenerative disease.
@en
prefLabel
Progranulin in neurodegenerative disease.
@en
P1476
Progranulin in neurodegenerative disease.
@en
P2093
Terri L Petkau
P304
P356
10.1016/J.TINS.2014.04.003
P577
2014-05-04T00:00:00Z