Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling - Wikidata - wikimedia - TriplyDB

Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling

Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling

http://www.wikidata.org/entity/Q38289224

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Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1 Carboxy terminal tail of polycystin-1 regulates localization of TSC2 to repress mTOR Two mutations in human BICC1 resulting in Wnt pathway hyperactivity associated with cystic renal dysplasia Autosomal dominant polycystic kidney disease: the last 3 years Role of the Polycystins in Cell Migration, Polarity, and Tissue Morphogenesis A polycystin-centric view of cyst formation and disease: the polycystins revisited Wnt and planar cell polarity signaling in cystic renal disease The role of the cilium in normal and abnormal cell cycles: emphasis on renal cystic pathologies Localization of retinitis pigmentosa 2 to cilia is regulated by Importin beta2.Signaling mechanisms implicated in cranial sutures pathophysiology: Craniosynostosis Systems biology of polycystic kidney disease: a critical review The ciliary protein nephrocystin-4 translocates the canonical Wnt regulator Jade-1 to the nucleus to negatively regulate β-catenin signaling Whole-exome sequencing reveals LRP5 mutations and canonical Wnt signaling associated with hepatic cystogenesis Impaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy HDAC6 is overexpressed in cystic cholangiocytes and its inhibition reduces cystogenesis Pkd1 regulates lymphatic vascular morphogenesis during development Protein kinase A-dependent pSer(675) -β-catenin, a novel signaling defect in a mouse model of congenital hepatic fibrosis Advances in the pathogenesis and treatment of polycystic kidney disease Identification of a polycystin-1 cleavage product, P100, that regulates store operated Ca entry through interactions with STIM1.Molecular advances in autosomal dominant polycystic kidney disease.Treatment strategies and clinical trial design in ADPKD Role of the polycytin-primary cilia complex in bone development and mechanosensing Dynamics of the G protein-coupled vasopressin V2 receptor signaling network revealed by quantitative phosphoproteomics.Interactions between β-catenin and the HSlo potassium channel regulates HSlo surface expression The cell biology of polycystic kidney disease Kidney: polycystic kidney disease.Genetic variation of DKK3 may modify renal disease severity in ADPKD.Systems biology of autosomal dominant polycystic kidney disease (ADPKD): computational identification of gene expression pathways and integrated regulatory networks.Detecting the surface localization and cytoplasmic cleavage of membrane-bound proteins.Effect of PKD1 gene missense mutations on polycystin-1 membrane topogenesis.Polycystin-1 and Gα12 regulate the cleavage of E-cadherin in kidney epithelial cells Loss of vinculin and membrane-bound β-catenin promotes metastasis and predicts poor prognosis in colorectal cancer The Wnt inhibitory factor 1 (WIF1) is targeted in glioblastoma and has a tumor suppressing function potentially by induction of senescence Fibrosis and progression of autosomal dominant polycystic kidney disease (ADPKD).Aquaporin-1 retards renal cyst development in polycystic kidney disease by inhibition of Wnt signaling.Expression of a naturally occurring angiotensin AT(1) receptor cleavage fragment elicits caspase-activation and apoptosis.Induction of Ran GTP drives ciliogenesis Lessons from in vitro studies and a related intracellular angiotensin II transgenic mouse model.c-Met and NF-κB-dependent overexpression of Wnt7a and -7b and Pax2 promotes cystogenesis in polycystic kidney disease.

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Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling

http://www.wikidata.org/entity/Q38289224

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

@zh-hans

2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

Polycystin-1 C-terminal tail a ...... hibits canonical Wnt signaling

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type

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Polycystin-1 C-terminal tail a ...... hibits canonical Wnt signaling

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Polycystin-1 C-terminal tail a ...... hibits canonical Wnt signaling

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Human Molecular Genetics

P1476

Polycystin-1 C-terminal tail a ...... hibits canonical Wnt signaling

@en

P2093

David M Merrick

http://www.w3.org/2001/XMLSchema#string

Jennifer L Pluznick

http://www.w3.org/2001/XMLSchema#string

Mark Lal

http://www.w3.org/2001/XMLSchema#string

Michael J Caplan

http://www.w3.org/2001/XMLSchema#string

Norman D Rosenblum

http://www.w3.org/2001/XMLSchema#string

Valeria Di Giovanni

http://www.w3.org/2001/XMLSchema#string

Veronique Chauvet

http://www.w3.org/2001/XMLSchema#string

Xuewen Song

http://www.w3.org/2001/XMLSchema#string

York Pei

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P2860

Interaction of frizzled related protein (FRP) with Wnt ligands and the frizzled receptor suggests alternative mechanisms for FRP inhibition of Wnt signaling

Three-dimensional structure of the armadillo repeat region of beta-catenin

Wnt signals are transmitted through N-terminally dephosphorylated beta-catenin

Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus

Cystic renal neoplasia following conditional inactivation of apc in mouse renal tubular epithelium

Nuclear localization of beta-catenin and loss of apical brush border actin in cystic tubules of bcl-2 -/- mice

Inversin, the gene product mutated in nephronophthisis type II, functions as a molecular switch between Wnt signaling pathways

WNT and beta-catenin signalling: diseases and therapies

Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations

Distinct molecular forms of beta-catenin are targeted to adhesive or transcriptional complexes.

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3105-3117

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scholarly article

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10.1093/HMG/DDN208

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20

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P478

17

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Cara J Gottardi

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2008-07-16T00:00:00Z

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51407264

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18632682

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2722884

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