Effects of changing glutamate 487 to lysine in rat and human liver mitochondrial aldehyde dehydrogenase. A model to study human (Oriental type) class 2 aldehyde dehydrogenase.
about
The three-dimensional structural basis of type II hyperprolinemiaThe mutation in the mitochondrial aldehyde dehydrogenase (ALDH2) gene responsible for alcohol-induced flushing increases turnover of the enzyme tetramers in a dominant fashionNon-P450 aldehyde oxidizing enzymes: the aldehyde dehydrogenase superfamilyStructure of betaine aldehyde dehydrogenase at 2.1 A resolutionThe aldehyde dehydrogenase ALDH2*2 allele exhibits dominance over ALDH2*1 in transduced HeLa cellsMolecular characterization of genes of Pseudomonas sp. strain HR199 involved in bioconversion of vanillin to protocatechuateGlu504Lys Single Nucleotide Polymorphism of Aldehyde Dehydrogenase 2 Gene and the Risk of Human DiseasesHuman liver mitochondrial aldehyde dehydrogenase: Three-dimensional structure and the restoration of solubility and activity of chimeric formsStructural and Functional Consequences of Coenzyme Binding to the Inactive Asian Variant of Mitochondrial Aldehyde Dehydrogenase: ROLES OF RESIDUES 475 AND 487Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variantConserved Catalytic Residues of the ALDH1L1 Aldehyde Dehydrogenase Domain Control Binding and Discharging of the CoenzymeMolecular cloning, characterization, and potential roles of cytosolic and mitochondrial aldehyde dehydrogenases in ethanol metabolism in Saccharomyces cerevisiae.Catalytic contribution of threonine 244 in human ALDH2NADH fluorescence lifetime analysis of the effect of magnesium ions on ALDH2Disruption of the coenzyme binding site and dimer interface revealed in the crystal structure of mitochondrial aldehyde dehydrogenase "Asian" variant.Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin.Interaction between the functional polymorphisms of the alcohol-metabolism genes in protection against alcoholism.Targeting aldehyde dehydrogenase 2: new therapeutic opportunities.Relationship between genetic polymorphisms of alcohol and aldehyde dehydrogenases and esophageal squamous cell carcinoma risk in males.Discovery of a series of aromatic lactones as ALDH1/2-directed inhibitors.Differential metabolism of organic nitrates by aldehyde dehydrogenase 1a1 and 2: substrate selectivity, enzyme inactivation, and active cysteine sites.ALDH2(E487K) mutation increases protein turnover and promotes murine hepatocarcinogenesis.Characterization of E. coli tetrameric aldehyde dehydrogenases with atypical properties compared to other aldehyde dehydrogenases.Role of CYP2E1 in mitochondrial dysfunction and hepatic tissue injury in alcoholic and non-alcoholic diseases.Genes encoding enzymes involved in ethanol metabolismRoles of defective ALDH2 polymorphism on liver protection and cancer development.Enhancement of coenzyme binding by a single point mutation at the coenzyme binding domain of E. coli lactaldehyde dehydrogenase.Differences in the roles of conserved glutamic acid residues in the active site of human class 3 and class 2 aldehyde dehydrogenasesCharacterization of the East Asian variant of aldehyde dehydrogenase-2: bioactivation of nitroglycerin and effects of Alda-1.A comparison of nitrophenyl esters and lactones as substrates of cytosolic aldehyde dehydrogenase.Inhibition of the Aldehyde Dehydrogenase 1/2 Family by Psoralen and Coumarin Derivatives.
P2860
Q24315802-1D76CCA1-0373-4582-A591-8A864BE16517Q24318592-698ACBB3-D936-4948-AF34-7F0286B1527DQ24655095-99D57652-3E63-4A9A-A789-A523232FAE08Q24673324-0217C89E-6CAB-4BA6-AF5D-78411C052494Q24677464-5DD80E1F-249D-4F69-A23F-FA1C6F6FACD5Q24679043-48EEB505-D420-4983-8116-6FA36FAE1EECQ26822811-4AB94FDE-67F6-453E-AE17-50C7D4B80B99Q27620972-15383230-D9D0-400E-9734-5D1699A73B71Q27643918-439D3054-2851-4F9F-A6BF-9E73400D8C4BQ27658903-96E5E1A4-5E38-459F-90CA-4FC292E04855Q27667677-68B2B86A-EAB0-46C5-9E65-874E66A9099DQ27930982-5A9418BA-7830-4C72-9838-536C5DA53B46Q28282806-72CE8FD2-FA38-40CA-B923-22D22DB72814Q28574531-45767423-80EB-4855-A62A-FDFB64F26048Q34093072-59C90CE0-5C26-42A0-9308-A82D747E6F70Q34312771-6E0CE52A-46FB-480F-80F7-1E29668A9D82Q34390264-9EE3C5DB-DA4A-422E-BAC2-D232A659F2DEQ34395219-760B733C-2A77-4DF1-A2D4-00579D7239CEQ35059686-2ADC603D-F5DC-43B5-BA03-1AF1B2C60F84Q35553100-53559913-35B2-4845-B576-3AD652327AA9Q35595779-077FA5FE-05F8-41A4-AC4F-53B94CA0DB52Q35895457-3AA2E0EE-3573-49C8-9FE1-D11DD65B7EC1Q36458445-F063B751-71AC-4305-A5CB-2A4E54C1BF0DQ36590615-88C53F8B-0578-47DD-A97C-83A9F77040ACQ37130460-291574FA-D0F8-438F-A4E3-E2D869A876EDQ38974718-499A4FFE-C123-45B8-A517-E77B8B8794F7Q41828734-90B979B8-A3A2-42CD-BED3-1BF6012CF6CFQ41845211-9C36AA30-6ED8-4622-9743-40A905AC5171Q41965258-2A16D811-5647-44E6-85CC-729BAED687EAQ42982214-C35482D4-4761-4982-A485-028B1DB3D91BQ46415124-38FE34B5-1462-42DD-8AAF-6A12BDD59615
P2860
Effects of changing glutamate 487 to lysine in rat and human liver mitochondrial aldehyde dehydrogenase. A model to study human (Oriental type) class 2 aldehyde dehydrogenase.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Effects of changing glutamate ...... lass 2 aldehyde dehydrogenase.
@en
type
label
Effects of changing glutamate ...... lass 2 aldehyde dehydrogenase.
@en
prefLabel
Effects of changing glutamate ...... lass 2 aldehyde dehydrogenase.
@en
P2093
P1476
Effects of changing glutamate ...... lass 2 aldehyde dehydrogenase.
@en
P2093
P304
13854-13860
P407
P577
1994-05-01T00:00:00Z