Mechanism of inhibition of HIV-1 integrase by G-tetrad-forming oligonucleotides in Vitro.
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Stacking of G-quadruplexes: NMR structure of a G-rich oligonucleotide with potential anti-HIV and anticancer activityThe fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif.An interlocked dimeric parallel-stranded DNA quadruplex: a potent inhibitor of HIV-1 integrase.HIV-1 IN inhibitors: 2010 update and perspectivesBiochemical and pharmacological analyses of HIV-1 integrase flexible loop mutants resistant to raltegravirDeveloping G-quartet oligonucleotides as novel anti-HIV agents: focus on anti-HIV drug design.Newly designed six-membered azasugar nucleotide-containing phosphorothioate oligonucleotides as potent human immunodeficiency virus type 1 inhibitors.Identification of a novel domain of fibroblast growth factor 2 controlling its angiogenic properties.Enhanced anti-HIV-1 activity of G-quadruplexes comprising locked nucleic acids and intercalating nucleic acidsDNA duplexes with hydrophobic modifications inhibit fusion between HIV-1 and cell membranes.Biophysical and biological properties of quadruplex oligodeoxyribonucleotidesAzasugar-containing phosphorothioate oligonucleotide (AZPSON) DBM-2198 inhibits human immunodeficiency virus type 1 (HIV-1) replication by blocking HIV-1 gp120 without affecting the V3 region.The quest for an efficacious antiviral for respiratory syncytial virus.G-quadruplex structures and their interaction diversity with ligands.NMR evaluation of ammonium ion movement within a unimolecular G-quadruplex in solution.Stable Domain Assembly of a Monomolecular DNA Quadruplex: Implications for DNA-Based NanoswitchesNovel bimodular DNA aptamers with guanosine quadruplexes inhibit phylogenetically diverse HIV-1 reverse transcriptases.A single molecule study of a fluorescently labeled telomestatin derivative and G-quadruplex interactions.Synthesis of unimolecularly circular G-quadruplexes as prospective molecular probes.6-oxocytidine containing oligonucleotides inhibit the HIV-1 integrase in vitro.d(GGGT) 4 and r(GGGU) 4 are both HIV-1 inhibitors and interleukin-6 receptor aptamers.Quadruplex formation as a molecular switch to turn on intrinsically fluorescent nucleotide analogs.Molecular dynamics of HIV1-integrase in complex with 93del - a structural perspective on the mechanism of inhibition.Cation binding to 15-TBA quadruplex DNA is a multiple-pathway cation-dependent process.Discovery of novel anti-HIV active G-quadruplex-forming oligonucleotides.Collision-induced dissociation of dimeric G-quadruplexes of HIV-1 integrase inhibitors and their complexes by tandem-in-time mass spectrometry.Multifunctional G-quadruplex aptamers and their application to protein detection.Effects of site-specific guanine C8-modifications on an intramolecular DNA G-quadruplexHIV-1 integrase inhibitor T30177 forms a stacked dimeric G-quadruplex structure containing bulges.Influence of loop size on the stability of intramolecular DNA quadruplexesEffects of monovalent cations on folding kinetics of G-quadruplexesInteraction of human nuclear topoisomerase I with guanosine quartet-forming and guanosine-rich single-stranded DNA and RNA oligonucleotides.Structural investigations on the anti-HIV G-quadruplex-forming oligonucleotide TGGGAG and its analogues: evidence for the presence of an A-tetrad.Cytotoxicity of guanine-based degradation products contributes to the antiproliferative activity of guanine-rich oligonucleotides.Interaction of hemin with quadruplex DNA.
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P2860
Mechanism of inhibition of HIV-1 integrase by G-tetrad-forming oligonucleotides in Vitro.
description
2000 nî lūn-bûn
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2000年の論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年論文
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2000年论文
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2000年论文
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name
Mechanism of inhibition of HIV-1 integrase by G-tetrad-forming oligonucleotides in Vitro.
@en
type
label
Mechanism of inhibition of HIV-1 integrase by G-tetrad-forming oligonucleotides in Vitro.
@en
prefLabel
Mechanism of inhibition of HIV-1 integrase by G-tetrad-forming oligonucleotides in Vitro.
@en
P2093
P2860
P356
P1476
Mechanism of inhibition of HIV-1 integrase by G-tetrad-forming oligonucleotides in Vitro.
@en
P2093
P2860
P304
21460-21467
P356
10.1074/JBC.M001436200
P407
P577
2000-07-01T00:00:00Z