Cleavage of full-length beta APP mRNA by hammerhead ribozymes.
about
The effect of structure in a long target RNA on ribozyme cleavage efficiency.Selection of efficient cleavage sites in target RNAs by using a ribozyme expression library.Facilitator oligonucleotides increase ribozyme RNA binding to full-length RNA substrates in vitro.Oligonucleotide facilitators may inhibit or activate a hammerhead ribozymePeptide nucleic acid (PNA) is capable of enhancing hammerhead ribozyme activity with long but not with short RNA substrates.Ribozyme mediated degradation of beta-amyloid peptide precursor mRNA in COS-7 cells.Comparative analysis of cleavage rates after systematic permutation of the NUX consensus target motif for hammerhead ribozymes.Extension of helix II of an HIV-1-directed hammerhead ribozyme with long antisense flanks does not alter kinetic parameters in vitro but causes loss of the inhibitory potential in living cells.A three-nucleotide helix I is sufficient for full activity of a hammerhead ribozyme: advantages of an asymmetric design.Hammerhead ribozyme kinetics.Efficient hammerhead ribozymes targeted to the polycistronic Sendai virus P/C mRNA. Structure-function relationships.In vitro selection of adenine-dependent ribozyme against Tpl2/Cot oncogene.Development of an efficient cis-trans-cis ribozyme cassette to inactivate plant genes.
P2860
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P2860
Cleavage of full-length beta APP mRNA by hammerhead ribozymes.
description
1993 nî lūn-bûn
@nan
1993年の論文
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1993年学术文章
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1993年学术文章
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1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
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1993年學術文章
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name
Cleavage of full-length beta APP mRNA by hammerhead ribozymes.
@en
type
label
Cleavage of full-length beta APP mRNA by hammerhead ribozymes.
@en
prefLabel
Cleavage of full-length beta APP mRNA by hammerhead ribozymes.
@en
P2860
P356
P1476
Cleavage of full-length beta APP mRNA by hammerhead ribozymes.
@en
P2093
R B Denman
P2860
P304
P356
10.1093/NAR/21.17.4119
P407
P577
1993-08-01T00:00:00Z