about
Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38.MAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitmentThe p38 MAPK pathway inhibits tristetraprolin-directed decay of interleukin-10 and pro-inflammatory mediator mRNAs in murine macrophagesIdentification of a novel AU-rich-element-binding protein which is related to AUF1Mitogen-activated protein kinase-activated protein kinase 2 regulates tumor necrosis factor mRNA stability and translation mainly by altering tristetraprolin expression, stability, and binding to adenine/uridine-rich elementPARP-14 combines with tristetraprolin in the selective posttranscriptional control of macrophage tissue factor expression.Role of mitogen-activated protein kinase phosphatase-1 in corticosteroid insensitivity of chronic oxidant lung injury.Post-transcriptional regulation of gene expression by mitogen-activated protein kinase p38.MAP kinase phosphatase 1: a novel mediator of biological effects of glucocorticoids?Crosstalk between glucocorticoids and mitogen-activated protein kinase signalling pathways.Basal protein phosphatase 2A activity restrains cytokine expression: role for MAPKs and tristetraprolinDominant Suppression of Inflammation via Targeted Mutation of the mRNA Destabilizing Protein Tristetraprolin.Dual-Specificity Phosphatase 1 and Tristetraprolin Cooperate To Regulate Macrophage Responses to LipopolysaccharideThe involvement of AU-rich element-binding proteins in p38 mitogen-activated protein kinase pathway-mediated mRNA stabilisation.Role of dual specificity phosphatases in biological responses to glucocorticoids.Maps and legends: the quest for dissociated ligands of the glucocorticoid receptor.The p38 MAPK Pathway in Rheumatoid Arthritis: A Sideways Look.Activating protein phosphatase 2A (PP2A) enhances tristetraprolin (TTP) anti-inflammatory function in A549 lung epithelial cells.Temporal regulation of cytokine mRNA expression by tristetraprolin: dynamic control by p38 MAPK and MKP-1.Regulation of cyclooxygenase 2 mRNA stability by the mitogen-activated protein kinase p38 signaling cascadeDexamethasone destabilizes cyclooxygenase 2 mRNA by inhibiting mitogen-activated protein kinase p38.Anti-inflammatory effects of selective glucocorticoid receptor modulators are partially dependent on up-regulation of dual specificity phosphatase 1The stability of tristetraprolin mRNA is regulated by mitogen-activated protein kinase p38 and by tristetraprolin itself.Regulation of tumour necrosis factor alpha mRNA stability by the mitogen-activated protein kinase p38 signalling cascade.Antiinflammatory effects of dexamethasone are partly dependent on induction of dual specificity phosphatase 1.Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells.Mkp1 is a c-Jun target gene that antagonizes JNK-dependent apoptosis in sympathetic neuronsGlucocorticoid regulation of mouse and human dual specificity phosphatase 1 (DUSP1) genes: unusual cis-acting elements and unexpected evolutionary divergence.IL-10 inhibits transcription elongation of the human TNF gene in primary macrophages.Aurothiomalate inhibits cyclooxygenase 2, matrix metalloproteinase 3, and interleukin-6 expression in chondrocytes by increasing MAPK phosphatase 1 expression and decreasing p38 phosphorylation: MAPK phosphatase 1 as a novel target for antirheumaticPosttranslational regulation of tristetraprolin subcellular localization and protein stability by p38 mitogen-activated protein kinase and extracellular signal-regulated kinase pathways.c-Jun N-terminal kinase primes endothelial cells at atheroprone sites for apoptosis.The p38 MAPK pathway mediates both antiinflammatory and proinflammatory processes: comment on the article by Damjanov and the editorial by Genovese.Stroma: the forgotten cells of innate immune memory.Stabilization of IFN- mRNA by MAPK p38 in IL-12- and IL-18-stimulated human NK cellsA p38 MAP kinase inhibitor regulates stability of interleukin-1-induced cyclooxygenase-2 mRNAp38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytesIncreased endothelial mitogen-activated protein kinase phosphatase-1 expression suppresses proinflammatory activation at sites that are resistant to atherosclerosisDual-specificity phosphatase 1-null mice exhibit spontaneous osteolytic disease and enhanced inflammatory osteolysis in experimental arthritisThe Role of TTP Phosphorylation in the Regulation of Inflammatory Cytokine Production by MK2/3
P50
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P50
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Andrew R. Clark
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Andrew R. Clark
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Andrew R. Clark
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Andrew R. Clark
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Andrew R. Clark
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Andrew R. Clark
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Andrew R. Clark
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