Growth inhibition of breast cancer cells by Grb2 downregulation is correlated with inactivation of mitogen-activated protein kinase in EGFR, but not in ErbB2, cells.
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Bivalent binding drives the formation of the Grb2-Gab1 signaling complex in a noncooperative mannerNovel inhibitors of a Grb2 SH3C domain interaction identified by a virtual screenShort-hairpin RNA-mediated stable silencing of Grb2 impairs cell growth and DNA synthesisGrb2 regulation of the actin-based cytoskeleton is required for ligand-independent EGF receptor-mediated oncogenesis.Expression profiling of gastric adenocarcinoma using cDNA array.Specificity and affinity motifs for Grb2 SH2-ligand interactionsMolecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery.Tobacco mosaic virus. Pioneering research for a century.Sphingosine kinase 1 isoform-specific interactions in breast cancerResveratrol attenuates the anticancer efficacy of paclitaxel in human breast cancer cells in vitro and in vivo.Luteolin and gefitinib regulation of EGF signaling pathway and cell cycle pathway genes in PC-3 human prostate cancer cells.Transcription factor and microRNA-regulated network motifs for cancer and signal transduction networks.High affinity molecules disrupting GRB2 protein complexes as a therapeutic strategy for chronic myelogenous leukaemia.Blood miRNomes and transcriptomes reveal novel longevity mechanisms in the long-lived bat, Myotis myotis.Liposomes to target peripheral neurons and Schwann cells.Liposomal delivery of nucleic acid-based anticancer therapeutics: BP-100-1.01.Disabled-2 small interfering RNA modulates cellular adhesive function and MAPK activity during megakaryocytic differentiation of K562 cells.Luteolin Regulation of Estrogen Signaling and Cell Cycle Pathway Genes in MCF-7 Human Breast Cancer Cells.Her2/neu induces all-trans retinoic acid (ATRA) resistance in breast cancer cells.HER2/neu reduces the apoptotic effects of N-(4-hydroxyphenyl)retinamide (4-HPR) in breast cancer cells by decreasing nitric oxide production.Troglitazone inhibits cell proliferation by attenuation of epidermal growth factor receptor signaling independent of peroxisome proliferator-activated receptor gamma.Aberrant expression of epidermal growth factor receptor and its interaction with protein kinase C δ in inflammation associated neoplastic transformation of human esophageal epithelium in high risk populations.Overexpression of Grb2 in inflammatory lesions and preneoplastic foci and tumors induced by N-nitrosodimethylamine in Helicobacter hepaticus-infected and -noninfected A/J mice.Grb2 signaling in cell motility and cancer
P2860
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P2860
Growth inhibition of breast cancer cells by Grb2 downregulation is correlated with inactivation of mitogen-activated protein kinase in EGFR, but not in ErbB2, cells.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Growth inhibition of breast ca ...... EGFR, but not in ErbB2, cells.
@en
type
label
Growth inhibition of breast ca ...... EGFR, but not in ErbB2, cells.
@en
prefLabel
Growth inhibition of breast ca ...... EGFR, but not in ErbB2, cells.
@en
P2093
P2860
P356
P1433
P1476
Growth inhibition of breast ca ...... EGFR, but not in ErbB2, cells.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1202422
P407
P577
1999-02-01T00:00:00Z
P5875
P6179
1037764312