Molecular signature of retinoic acid treatment in acute promyelocytic leukemia.
about
Pirin downregulation is a feature of AML and leads to impairment of terminal myeloid differentiationNotch1 regulates the expression of the multidrug resistance gene ABCC1/MRP1 in cultured cancer cellsTranscriptomic response to differentiation induction.AML1/ETO oncoprotein is directed to AML1 binding regions and co-localizes with AML1 and HEB on its targets.HIF factors cooperate with PML-RARα to promote acute promyelocytic leukemia progression and relapseDimerization-induced corepressor binding and relaxed DNA-binding specificity are critical for PML/RARA-induced immortalization.Molecular concepts analysis links tumors, pathways, mechanisms, and drugsPKCδ Regulates Translation Initiation through PKR and eIF2α in Response to Retinoic Acid in Acute Myeloid Leukemia CellsChromatin modifications induced by PML-RARalpha repress critical targets in leukemogenesis as analyzed by ChIP-Chip.PML-RARα co-operates with Sox4 in acute myeloid leukemia development in miceMBD3, a component of the NuRD complex, facilitates chromatin alteration and deposition of epigenetic marks.Notch signaling in acute promyelocytic leukemiaPharmacogenetics in reproductive and perinatal medicine.PML/RARa inhibits PTEN expression in hematopoietic cells by competing with PU.1 transcriptional activity.Lymphoid enhancer binding factor-1 (LEF1) expression as a prognostic factor in adult acute promyelocytic leukemia.MicroRNA gene expression during retinoic acid-induced differentiation of human acute promyelocytic leukemia.Chronic toxicological effects of β-diketone antibiotics on Zebrafish (Danio rerio) using transcriptome profiling of deep sequencing.Aberrant association of promyelocytic leukemia protein-retinoic acid receptor-alpha with coactivators contributes to its ability to regulate gene expression.Opposite Effects of SET7/9 on Apoptosis of Human Acute Myeloid Leukemia Cells and Lung Cancer Cells.Pharmacogenetic model of retinoic acid-induced dyslipidemia and insulin resistance.Superenhancer Analysis Defines Novel Epigenomic Subtypes of Non-APL AML, Including an RARα Dependency Targetable by SY-1425, a Potent and Selective RARα Agonist.Opinion: how patients have benefited from mouse models of acute promyelocytic leukaemia.The acute promyelocytic leukaemia success story: curing leukaemia through targeted therapies.
P2860
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P2860
Molecular signature of retinoic acid treatment in acute promyelocytic leukemia.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Molecular signature of retinoic acid treatment in acute promyelocytic leukemia.
@en
type
label
Molecular signature of retinoic acid treatment in acute promyelocytic leukemia.
@en
prefLabel
Molecular signature of retinoic acid treatment in acute promyelocytic leukemia.
@en
P2093
P2860
P50
P356
P1433
P1476
Molecular signature of retinoic acid treatment in acute promyelocytic leukemia.
@en
P2093
Heiko Müller
Natalia Meani
Pier Giuseppe Pelicci
Silvia Licciulli
Vania Gelmetti
P2860
P2888
P304
P356
10.1038/SJ.ONC.1208498
P407
P577
2005-05-01T00:00:00Z
P5875
P6179
1035114993