Chromatin modifications induced by PML-RARalpha repress critical targets in leukemogenesis as analyzed by ChIP-Chip.
about
Lysine deacetylase (KDAC) regulatory pathways: an alternative approach to selective modulationERG transcriptional networks in primary acute leukemia cells implicate a role for ERG in deregulated kinase signalingIdentification of a myeloid committed progenitor as the cancer-initiating cell in acute promyelocytic leukemia.Evaluating oligonucleotide properties for DNA microarray probe design.Characterisation of genome-wide PLZF/RARA target genes.Profiling of histone H3 lysine 9 trimethylation levels predicts transcription factor activity and survival in acute myeloid leukemia.A protease-resistant PML-RAR{alpha} has increased leukemogenic potential in a murine model of acute promyelocytic leukemiaCHK1 plays a critical role in the anti-leukemic activity of the wee1 inhibitor MK-1775 in acute myeloid leukemia cells.EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation.XXIII International Association for Comparative Research on Leukemia and Related Diseases Symposium: from molecular pathogenesis to targeted therapy in leukemia and solid tumors.Epigenetic distortion to VDR transcriptional regulation in prostate cancer cells.PML/RARα-Regulated miR-181a/b Cluster Targets the Tumor Suppressor RASSF1A in Acute Promyelocytic Leukemia.A critical appraisal of tools available for monitoring epigenetic changes in clinical samples from patients with myeloid malignancies.Egr1 regulates the coordinated expression of numerous EGF receptor target genes as identified by ChIP-on-chipNotch signaling in acute promyelocytic leukemiaApplications of microarray technology to Acute Myelogenous LeukemiaDNA methylation profiling in acute myeloid leukemia: from recent technological advances to biological and clinical insights.The PML-Interacting Protein DAXX: Histone Loading Gets into the Picture.Origins of aberrant DNA methylation in acute myeloid leukemia.Differentiation therapy of acute myeloid leukemia.Epigenetics in acute promyelocytic leukaemia pathogenesis and treatment response: a TRAnsition to targeted therapies.Cell-specific interaction of retinoic acid receptors with target genes in mouse embryonic fibroblasts and embryonic stem cells.Repression of CDKN2C caused by PML/RARα binding promotes the proliferation and differentiation block in acute promyelocytic leukemia.PML protein organizes heterochromatin domains where it regulates histone H3.3 deposition by ATRX/DAXX.Sensitivity of MLL-rearranged AML cells to all-trans retinoic acid is associated with the level of H3K4me2 in the RARα promoter region.Significance of Inactivated Genes in Leukemia: Pathogenesis and PrognosisCoordinated regulation of the immunoproteasome subunits by PML/RARα and PU.1 in acute promyelocytic leukemia.Interaction with RXR is necessary for NPM-RAR-induced myeloid differentiation blockade.The limited contribution of DNA methylation to PML-RARα induced leukemia.Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia.
P2860
Q27021965-43CE2701-4F2A-4C62-97B0-19D99EF3A790Q28484833-30C19055-F36D-4EC8-AB52-5517545FAEDCQ33560404-E106504C-EF9E-4021-B696-56486FA2D93EQ33922353-FFB32110-DBC9-4082-8DEA-FA47BB433CC8Q34031285-D422C839-80A0-485B-B0BF-4542C7022B9EQ34310541-E8BC917E-C6ED-4957-BA12-DA14634021B7Q34310547-6CDD0E05-D72D-4006-BDB2-5A002A8483BDQ34544769-D592ACC7-2305-4E78-B807-BBE9B4D3CAAAQ34963463-5867A432-B3FD-47CE-940B-A86A49BC8B82Q35138140-C6B082A5-A1BB-46B4-97C0-AAC283ABFAC2Q35600481-402A8774-500E-4B3B-919B-FD777024AD7EQ35958274-B09347D0-896F-494B-BB19-75EBF5C27AE2Q36216230-63DAA907-A32D-4329-A953-B75038448F96Q37038586-6B2B8744-5F8E-41DF-A503-840BBEFB77DCQ37414175-30EE811B-5437-4D80-95CC-0111168F5154Q37437233-AA3B8B80-FFE0-4F2B-9D54-AE3FBF7D418CQ37797467-7A392D5F-7E47-4EF5-ABFA-A250C25024F2Q38113966-8F6BE0B8-8CD7-4B7E-B67E-63993D97C357Q38130091-7F53257D-42AD-467F-AD26-747B3504B196Q38161360-08C33C26-D619-411F-8194-F9FE614EDEC9Q38253382-D7B0505E-CEA9-464C-AC95-B8407EBFC0BDQ38349181-48563EE5-7CBF-4541-B988-8C86E4179C2AQ38728895-14ACEC6D-B3D0-49A3-A6BE-776D90E5F685Q38877286-8166DEBF-B68C-466C-8882-4D8F31FD4D56Q39029755-61269BE4-C834-44B1-A295-D9E8B734D865Q39350173-E7E772A8-AAE9-49CE-A735-9C0C6612E900Q42440049-21D71AAF-E57A-4079-BEB0-1935533893CAQ42730910-39F44E7A-9F7C-473C-B291-8DE490635E56Q43105349-315ED48D-4AA5-4E85-A978-A9AF3E996516Q55399708-E9565175-D05A-42F3-8873-A609729EEB1A
P2860
Chromatin modifications induced by PML-RARalpha repress critical targets in leukemogenesis as analyzed by ChIP-Chip.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Chromatin modifications induce ...... esis as analyzed by ChIP-Chip.
@ast
Chromatin modifications induce ...... esis as analyzed by ChIP-Chip.
@en
type
label
Chromatin modifications induce ...... esis as analyzed by ChIP-Chip.
@ast
Chromatin modifications induce ...... esis as analyzed by ChIP-Chip.
@en
prefLabel
Chromatin modifications induce ...... esis as analyzed by ChIP-Chip.
@ast
Chromatin modifications induce ...... esis as analyzed by ChIP-Chip.
@en
P2093
P2860
P50
P1433
P1476
Chromatin modifications induce ...... esis as analyzed by ChIP-Chip.
@en
P2093
Abdul Peerzada
Christine Disselhoff
Claudia Hoemme
Fabienne Isken
Gerhard Behre
Kay Nieselt
Matthias Zschunke
Nicola Tidow
Shuchi Agrawal
Wolfgang E Berdel
P2860
P304
P356
10.1182/BLOOD-2007-03-079921
P407
P577
2007-11-16T00:00:00Z