Cleavage of oligoribonucleotides by a ribozyme derived from the hepatitis delta virus RNA sequence.
about
Efficient trans-cleavage of a stem-loop RNA substrate by a ribozyme derived from neurospora VS RNAStructural effects of nucleobase variations at key active site residue Ade38 in the hairpin ribozymeEnergetic contribution of non-essential 5' sequence to catalysis in a hepatitis delta virus ribozymeHepatitis delta virus: the molecular basis of laboratory diagnosis.Hidden ribozymes in eukaryotic genome sequenceA nested double pseudoknot is required for self-cleavage activity of both the genomic and antigenomic hepatitis delta virus ribozymes.Ribozyme cleavage of a 2,5-phosphodiester linkage: mechanism and a restricted divalent metal-ion requirement.Analysis of the cleavage reaction of a trans-acting human hepatitis delta virus ribozyme.Mutagenesis analysis of a hepatitis delta virus genomic ribozyme.Ribozyme-based gene-inactivation systems require a fine comprehension of their substrate specificities; the case of delta ribozymeRandom mutations to evaluate the role of bases at two important single-stranded regions of genomic HDV ribozyme.Hydrolysis of oligoribonucleotides: influence of sequence and length.Mutagenesis analysis of the self-cleavage domain of hepatitis delta virus antigenomic RNAUse of ribozymes and antisense oligodeoxynucleotides to investigate mechanisms of drug resistanceIn vitro selection of self-cleaving RNAs with a low pH optimumThe poly(A) site sequence in HDV RNA alters both extent and rate of self-cleavage of the antigenomic ribozymeRibozyme-mediated high resistance against potato spindle tuber viroid in transgenic potatoes.Progress and outlook in structural biology of large viral RNAs.Facilitator oligonucleotides increase ribozyme RNA binding to full-length RNA substrates in vitro.Catalytic cleavage of cis- and trans-acting antigenomic delta ribozymes in the presence of various divalent metal ionsA universal method to produce in vitro transcripts with homogeneous 3' ends.Core sequences and a cleavage site wobble pair required for HDV antigenomic ribozyme self-cleavage.Folding of the HDV antigenomic ribozyme pseudoknot structure deduced from long-range photocrosslinks.Core-associated non-duplex sequences distinguishing the genomic and antigenomic self-cleaving RNAs of hepatitis delta virus.A pseudoknot in the 3' non-core region of the glmS ribozyme enhances self-cleavage activity.3-D models of the antigenomic ribozyme of the hepatitis delta agent with eight new contacts suggested by sequence analysis of 188 cDNA clonesAssessment of disparate structural features in three models of the hepatitis delta virus ribozyme.A circular trans-acting hepatitis delta virus ribozyme.Substrate specificity of delta ribozyme cleavage.Kinetic analysis of delta ribozyme cleavage.A practical approach to generate suitable de novo synthesis RNA template for a flavivirus RNA-dependent RNA polymerase.Addition of an extra substrate binding site and partial destabilization of stem structures in HDV ribozyme give rise to high sequence-specificity for its target RNA.The effect of Lp3 enlargement on the folding and catalysis of hepatitis delta virus cis-cleaving ribozyme.An AU at the first base pair of helix 3 elevates the catalytic activity of hepatitis delta virus ribozymes.Circular ribozymes generated in Escherichia coli using group I self-splicing permuted intron-exon sequences.
P2860
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P2860
Cleavage of oligoribonucleotides by a ribozyme derived from the hepatitis delta virus RNA sequence.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh
1992年學術文章
@zh-hant
name
Cleavage of oligoribonucleotid ...... itis delta virus RNA sequence.
@en
type
label
Cleavage of oligoribonucleotid ...... itis delta virus RNA sequence.
@en
prefLabel
Cleavage of oligoribonucleotid ...... itis delta virus RNA sequence.
@en
P356
P1433
P1476
Cleavage of oligoribonucleotid ...... itis delta virus RNA sequence.
@en
P2093
P356
10.1021/BI00116A004
P407
P577
1992-01-01T00:00:00Z