Ethyl pyruvate inhibits nuclear factor-kappaB-dependent signaling by directly targeting p65.
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Multiple sclerosis: molecular mechanisms and therapeutic opportunitiesConvergence of nitric oxide and lipid signaling: anti-inflammatory nitro-fatty acids.Nitrated fatty acids: Endogenous anti-inflammatory signaling mediatorsEthyl pyruvate protects against hypoxic-ischemic brain injury via anti-cell death and anti-inflammatory mechanisms.Thrombin promotes fibronectin secretion by bone marrow mesenchymal stem cells via the protease-activated receptor mediated signalling pathways.Nuclear factor kappaB inhibitors alleviate and the proteasome inhibitor PS-341 exacerbates radiation toxicity in zebrafish embryosResponses of cultured human keratocytes and myofibroblasts to ethyl pyruvate: a microarray analysis of gene expressionEthyl pyruvate has anti-inflammatory and delayed myocardial protective effects after regional ischemia/reperfusion injury.The apoptogenic toxin AIP56 is a metalloprotease A-B toxin that cleaves NF-κb P65Ethyl pyruvate improves survival in awake hemorrhage.Anti-inflammatory resuscitation improves survival in hemorrhage with trauma.Radiation protection of the gastrointestinal tract and growth inhibition of prostate cancer xenografts by a single compound.Postischemic treatment with ethyl pyruvate prevents adenosine triphosphate depletion, ameliorates inflammation, and decreases thrombosis in a murine model of hind-limb ischemia and reperfusionScientific and clinical challenges in sepsis.Soluble HMGB1 is a novel adipokine stimulating IL-6 secretion through RAGE receptor in SW872 preadipocyte cell line: contribution to chronic inflammation in fat tissueEthyl pyruvate inhibits HMGB1 phosphorylation and release by chelating calciumPreventive effects of ethyl pyruvate on endotoxin-induced uveitis in rats.Immunotherapeutic suppression of indoleamine 2,3-dioxygenase and tumor growth with ethyl pyruvate.Ethyl pyruvate preserves IGF-I sensitivity toward mTOR substrates and protein synthesis in C2C12 myotubes.Effects of ethyl pyruvate on leukocyte-endothelial interactions in the mesenteric microcirculation during early sepsis treatment.Can we predict the effects of NF-kappaB inhibition in sepsis? Studies with parthenolide and ethyl pyruvate.Ethyl pyruvate promotes spinal cord repair by ameliorating the glial microenvironment.Ethyl pyruvate ameliorates endotoxin-induced corneal inflammationHMGB1 in renal ischemic injury.Bench-to-bedside review: Amelioration of acute renal impairment using ethyl pyruvate.Update in critical care 2005.Ethyl pyruvate attenuated coxsackievirus B3-induced acute viral myocarditis by suppression of HMGB1/RAGE/NF-ΚB pathwayIntroduction of an agent-based multi-scale modular architecture for dynamic knowledge representation of acute inflammationMethyl-2-acetamidoacrylate, an ethyl pyruvate analog, decreases sepsis-induced acute kidney injury in mice.Ethyl pyruvate attenuates murine allergic rhinitis partly by decreasing high mobility group box 1 release.Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.Pyruvate protects against experimental stroke via an anti-inflammatory mechanism.Anti-inflammatory and anti-excitoxic effects of diethyl oxopropanamide, an ethyl pyruvate bioisoster, exert robust neuroprotective effects in the postischemic brain.Hydrogen sulfide suppresses oxidized low-density lipoprotein (ox-LDL)-stimulated monocyte chemoattractant protein 1 generation from macrophages via the nuclear factor κB (NF-κB) pathway.Effects of ethyl pyruvate on cardiac function recovery and apoptosis reduction after global cold ischemia and reperfusionMicroglial activation in stroke: therapeutic targets.Direct Rel/NF-κB inhibitors: structural basis for mechanism of action.Treatment of endotoxaemia and septicaemia in the equine patient.EOP, a newly synthesized ethyl pyruvate derivative, attenuates the production of inflammatory mediators via p38, ERK and NF-κB pathways in lipopolysaccharide-activated BV-2 microglial cells.Stimulation of FasL induces production of proinflammatory mediators through activation of mitogen-activated protein kinases and nuclear factor-κB in THP-1 cells.
P2860
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P2860
Ethyl pyruvate inhibits nuclear factor-kappaB-dependent signaling by directly targeting p65.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh
2004年學術文章
@zh-hant
name
Ethyl pyruvate inhibits nuclea ...... ing by directly targeting p65.
@en
type
label
Ethyl pyruvate inhibits nuclea ...... ing by directly targeting p65.
@en
prefLabel
Ethyl pyruvate inhibits nuclea ...... ing by directly targeting p65.
@en
P2093
P356
P1476
Ethyl pyruvate inhibits nuclea ...... ing by directly targeting p65.
@en
P2093
Joshua A Englert
Mitchell P Fink
Runkuan Yang
Russell L Delude
Yusheng Han
P304
P356
10.1124/JPET.104.079707
P407
P577
2004-11-03T00:00:00Z