Affinity purification and characterization of human O6-alkylguanine-DNA alkyltransferase complexed with BCNU-treated, synthetic oligonucleotide.
about
Current data and strategy in glioblastoma multiformeInfluence of glutathione and glutathione S-transferases on DNA interstrand cross-link formation by 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)hydrazine, the active anticancer moiety generated by laromustine.Repair-deficient 3-methyladenine DNA glycosylase homozygous mutant mouse cells have increased sensitivity to alkylation-induced chromosome damage and cell killing.DNA interstrand cross-linking and cytotoxicity induced by chloroethylnitrosoureas and cisplatin in human glioma cell lines which vary in cellular concentration of O6-alkylguanine-DNA alkyltransferase.S-alkylthiolation of O6-methylguanine-DNA-methyltransferase (MGMT) to sensitize cancer cells to anticancer therapy.The therapeutic potential of O6-alkylguanine DNA alkyltransferase inhibitors.Cancer pharmacogenomics: role of DNA repair genetic polymorphisms in individualizing cancer therapy.Evidence that covalent complex formation between BCNU-treated oligonucleotides and E. coli alkyltransferases requires the O6-alkylguanine function.DNA repair functions in heterologous cells.The chloroethylnitrosoureas: sensitivity and resistance to cancer chemotherapy at the molecular level.Expression of O⁶-methylguanine-DNA methyltransferase in childhood medulloblastoma.
P2860
Q33527073-9189896F-DA48-497C-AE2A-E665DAEA1775Q34065933-92E2B311-8894-4CD2-AA23-6B21F0E4ECB6Q35853590-45C28667-5D8E-4E37-AD4B-4D896ABA5AD3Q36116107-03D65A21-EAB2-4423-9ABC-1E8EAE8512E1Q36734940-BD482FC1-7AC2-4D2F-9D26-37E465DE9BF2Q36964700-590BC5F3-AD2A-4E3B-93E1-0F9A0AD8E416Q37031517-4B1DA385-2F1A-46FB-B0EF-E4264C23BD96Q40518061-4E857046-4944-4618-866E-64F2B229CE40Q41311787-4ACE505C-FE4F-4D6D-8957-936CC1C4C320Q41669418-CCD9960E-A107-4061-9F9D-BAA898FAB2CEQ54412464-C3788B8E-4DF9-400D-8418-C7636EEDA0E0
P2860
Affinity purification and characterization of human O6-alkylguanine-DNA alkyltransferase complexed with BCNU-treated, synthetic oligonucleotide.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Affinity purification and char ...... ed, synthetic oligonucleotide.
@en
type
label
Affinity purification and char ...... ed, synthetic oligonucleotide.
@en
prefLabel
Affinity purification and char ...... ed, synthetic oligonucleotide.
@en
P2860
P356
P1476
Affinity purification and char ...... ed, synthetic oligonucleotide.
@en
P2093
P E Gonzaga
P2860
P304
P356
10.1093/NAR/17.16.6581
P407
P577
1989-08-01T00:00:00Z