Mutations in two regions upstream of the A gamma globin gene canonical promoter affect gene expression.
about
A homeodomain protein binds to gamma-globin gene regulatory sequencesTranscription factors KLF1 and KLF2 positively regulate embryonic and fetal beta-globin genes through direct promoter bindingT to C substitution at -175 or -173 of the gamma-globin promoter affects GATA-1 and Oct-1 binding in vitro differently but can independently reproduce the hereditary persistence of fetal hemoglobin phenotype in transgenic micePhylogenetic footprinting reveals a nuclear protein which binds to silencer sequences in the human gamma and epsilon globin genesRegulatory mutations and human genetic disease.Protein-DNA interactions upstream from the human A gamma globin geneMethylation-enhanced binding of Sp1 to the stage selector element of the human gamma-globin gene promoter may regulate development specificity of expression.Roles of fetal G gamma-globin promoter elements and the adult beta-globin 3' enhancer in the stage-specific expression of globin genes.Analysis of the mechanism of action of non-deletion hereditary persistence of fetal hemoglobin mutants in transgenic mice.Modulation of the phenotypic diversity of sickle cell anemia.
P2860
Q24563215-DB0660D7-AFB0-4228-BD3F-84EBBA370F4FQ24632948-05D40109-CCE1-42B2-89DC-177FEF23BB0FQ28586736-AEAF5CD0-FB9D-419A-92D6-8928AA0AB7CEQ33339100-7B574675-E5F8-4E3C-B48F-7116B5B93417Q35164314-7658EFD9-EC94-4320-B5E2-D93305822E27Q35837183-38CB7004-EEB4-4463-8DC2-CDC0FF34E6CBQ36685090-1F31860F-1FF8-4F94-8CF4-B5B4BBD5A8CCQ36721219-DAE00952-2C62-4382-B87C-9C47F0BD4C5CQ39696919-4D89BBB5-FA9D-41BD-A8D9-265462F35376Q41068614-D941B6C8-1D95-433A-AA46-7C92F1F72B8A
P2860
Mutations in two regions upstream of the A gamma globin gene canonical promoter affect gene expression.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
Mutations in two regions upstr ...... omoter affect gene expression.
@en
type
label
Mutations in two regions upstr ...... omoter affect gene expression.
@en
prefLabel
Mutations in two regions upstr ...... omoter affect gene expression.
@en
P2093
P2860
P356
P1476
Mutations in two regions upstr ...... omoter affect gene expression.
@en
P2093
P2860
P304
P356
10.1093/NAR/17.11.4339
P407
P577
1989-06-01T00:00:00Z