Characterization of phenobarbital-inducible mouse Cyp2b10 gene transcription in primary hepatocytes.
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Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CARCross-repression, a functional consequence of the physical interaction of non-liganded nuclear receptors and POU domain transcription factorsInsights into CYP2B6-mediated drug-drug interactionsThe repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 geneFunctional interactions between an atypical NF-kappaB site from the rat CYP2B1 promoter and the transcriptional repressor RBP-Jkappa/CBF1.Coordinated regulation of nuclear receptor CAR by CCRP/DNAJC7, HSP70 and the ubiquitin-proteasome system.The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene.Regulation of cytochrome P450 (CYP) genes by nuclear receptors.CYP2B6: new insights into a historically overlooked cytochrome P450 isozymeTissue distribution and gender-divergent expression of 78 cytochrome P450 mRNAs in mice.Extracellular signal-regulated kinase is an endogenous signal retaining the nuclear constitutive active/androstane receptor (CAR) in the cytoplasm of mouse primary hepatocytes.Role of DNA methylation in the regulation of lipogenic glycerol-3-phosphate acyltransferase 1 gene expression in the mouse neonatal liver.Comparative cytochrome P450 proteomics in the livers of immunodeficient mice using 18O stable isotope labelingNonsterol Isoprenoids Activate Human Constitutive Androstane Receptor in an Isoform-Selective Manner in Primary Cultured Mouse Hepatocytes.p38 MAP Kinase Links CAR Activation and Inactivation in the Nucleus via Phosphorylation at Threonine 38.Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymesEstrogen receptor-dependent regulation of CYP2B6 in human breast cancer cells.A targeted in vivo SILAC approach for quantification of drug metabolism enzymes: regulation by the constitutive androstane receptor.Glucocorticoids and phenobarbital induce murine CYP2B genes by independent mechanisms.Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes.Identification of three novel natural product compounds that activate PXR and CAR and inhibit inflammationHuman nuclear pregnane X receptor cross-talk with CREB to repress cAMP activation of the glucose-6-phosphatase gene.Novel CAR-mediated mechanism for synergistic activation of two distinct elements within the human cytochrome P450 2B6 gene in HepG2 cells.The structure, function, and regulation of cytochrome P450 2A enzymes.A conserved nuclear receptor consensus sequence (DR-4) mediates transcriptional activation of the chicken CYP2H1 gene by phenobarbital in a hepatoma cell line.Transcriptional activation of cytochrome P450 genes by different classes of chemical inducers.Regulation of the major detoxication functions by phenobarbital and 3-methylcholanthrene in co-cultures of rat hepatocytes and liver epithelial cells.Modulation of murine phenobarbital-inducible CYP2A5, CYP2B10 and CYP1A enzymes by inhibitors of protein kinases and phosphatases.Specific and overlapping functions of the nuclear hormone receptors CAR and PXR in xenobiotic response.Protein serine/threonine phosphatase inhibitors suppress phenobarbital-induced Cyp2b10 gene transcription in mouse primary hepatocytes.Phosphorylated Nuclear Receptor CAR Forms a Homodimer To Repress Its Constitutive Activity for Ligand Activation.Localization of estradiol-responsive region in the phenobarbital-responsive enhancer module of mouse Cyp2b-10 gene.Acute sodium arsenite treatment induces Cyp2a5 but not Cyp1a1 in the C57Bl/6 mouse in a tissue (kidney) selective manner.In vivo activation of the constitutive androstane receptor beta (CARbeta) by treatment with dehydroepiandrosterone (DHEA) or DHEA sulfate (DHEA-S).Agonist-dependent and agonist-independent transactivations of the human constitutive androstane receptor are modulated by specific amino acid pairs.Clofibric acid induces hepatic CYP 2B1/2 via constitutive androstane receptor not via peroxisome proliferator activated receptor alpha in rat.Evidence against the Bm1P1 protein as a positive transcription factor for barbiturate-mediated induction of cytochrome P450BM-1 in bacillus megaterium.Characterization of a phenobarbital-responsive enhancer module in mouse P450 Cyp2b10 gene.Human MutSalpha specifically binds to DNA containing aminofluorene and acetylaminofluorene adducts.Multiplexed Isobaric Tag-Based Profiling of Seven Murine Tissues Following In Vivo Nicotine Treatment Using a Minimalistic Proteomics Strategy.
P2860
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P2860
Characterization of phenobarbital-inducible mouse Cyp2b10 gene transcription in primary hepatocytes.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Characterization of phenobarbi ...... iption in primary hepatocytes.
@en
type
label
Characterization of phenobarbi ...... iption in primary hepatocytes.
@en
prefLabel
Characterization of phenobarbi ...... iption in primary hepatocytes.
@en
P2093
P2860
P356
P1476
Characterization of phenobarbi ...... ription in primary hepatocytes
@en
P2093
P2860
P304
P356
10.1074/JBC.271.16.9746
P407
P577
1996-04-01T00:00:00Z