Reduction of expression of the multidrug resistance protein (MRP) in human tumor cells by antisense phosphorothioate oligonucleotides.
about
Predicting oligonucleotide affinity to nucleic acid targets.Antisense-induced down-regulation of thymidylate synthase and enhanced cytotoxicity of 5-FUdR in 5-FUdR-resistant HeLa cellsSilencing disease genes in the laboratory and the clinicAnthrapyridones, a novel group of antitumour non-cross resistant anthraquinone analogues. Synthesis and molecular basis of the cytotoxic activity towards K562/DOX cells.Subcellular daunorubicin distribution and its relation to multidrug resistance phenotype in drug-resistant cell line SMMC-7721/R.Identification of sequence motifs in oligonucleotides whose presence is correlated with antisense activityStrategies for reversing drug resistance.Improving cancer chemotherapy with modulators of ABC drug transporters.Use of ribozymes and antisense oligodeoxynucleotides to investigate mechanisms of drug resistanceMetabolism of ATP-binding cassette drug transporter inhibitors: complicating factor for multidrug resistance.Antisense oligonucleotides to class III beta-tubulin sensitize drug-resistant cells to TaxolNanomedicinal strategies to treat multidrug-resistant tumors: current progress.Reversal of ATP-binding cassette drug transporter activity to modulate chemoresistance: why has it failed to provide clinical benefit?An antisense oligodeoxynucleotide-doxorubicin conjugate: preparation and its reversal multidrug resistance of human carcinoma cell line in vitro.In vivo suppression of Bcl-XL expression facilitates chemotherapy-induced leukaemia cell death in a SCID/NOD-Hu model.Synthesis of new OBAN's and further studies on positioning of the catalytic group.In vitro and in vivo downregulation of MRP1 by antisense oligonucleotides: a potential role in neuroblastoma therapy.Coinhibition of overexpressed genes in acute myeloid leukemia subtype M2 by gold nanoparticles functionalized with five antisense oligonucleotides and one anti-CD33(+)/CD34(+) aptamer.
P2860
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P2860
Reduction of expression of the multidrug resistance protein (MRP) in human tumor cells by antisense phosphorothioate oligonucleotides.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Reduction of expression of the ...... phorothioate oligonucleotides.
@en
type
label
Reduction of expression of the ...... phorothioate oligonucleotides.
@en
prefLabel
Reduction of expression of the ...... phorothioate oligonucleotides.
@en
P2093
P1476
Reduction of expression of the ...... phorothioate oligonucleotides.
@en
P2093
P304
P356
10.1016/0006-2952(95)02220-1
P407
P577
1996-02-01T00:00:00Z