Cis and trans requirements for stable episomal maintenance of the BPV-1 replicator.
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The mitotic chromosome binding activity of the papillomavirus E2 protein correlates with interaction with the cellular chromosomal protein, Brd4.Effect of bovine papillomavirus E2 protein-specific monoclonal antibodies on papillomavirus DNA replication.Bromodomain protein 4 mediates the papillomavirus E2 transcriptional activation functionBrd4-independent transcriptional repression function of the papillomavirus e2 proteinsA bovine papillomavirus-1 based vector restores the function of the low-density lipoprotein receptor in the receptor-deficient CHO-ldlA7 cell lineAnalysis of the papillomavirus E2 and bromodomain protein Brd4 interaction using bimolecular fluorescence complementationCell-specific modulation of papovavirus replication by tumor suppressor protein p53Replication and encapsidation of papillomaviruses in Saccharomyces cerevisiaeMechanism of genomic instability in cells infected with the high-risk human papillomaviruses.Abrogation of the Brd4-positive transcription elongation factor B complex by papillomavirus E2 protein contributes to viral oncogene repressionDNA replication of human papillomavirus type 31 is modulated by elements of the upstream regulatory region that lie 5' of the minimal originPapillomavirus interaction with cellular chromatin.Bovine papillomavirus type 1 genomes and the E2 transactivator protein are closely associated with mitotic chromatin.Nuclear matrix attachment regions of human papillomavirus type 16 point toward conservation of these genomic elements in all genital papillomavirusesProteasome-mediated degradation of the papillomavirus E2-TA protein is regulated by phosphorylation and can modulate viral genome copy number.Reconstitution of papillomavirus E2-mediated plasmid maintenance in Saccharomyces cerevisiae by the Brd4 bromodomain protein.Interaction of bovine papillomavirus E2 protein with Brd4 stabilizes its association with chromatin.Inhibition of E2 binding to Brd4 enhances viral genome loss and phenotypic reversion of bovine papillomavirus-transformed cells.Variations in the association of papillomavirus E2 proteins with mitotic chromosomesE1 protein of bovine papillomavirus type 1 interferes with E2 protein-mediated tethering of the viral DNA to mitotic chromosomesMitotic chromosome-binding activity of latency-associated nuclear antigen 1 is required for DNA replication from terminal repeat sequence of Kaposi's sarcoma-associated herpesvirusEpisomal maintenance of plasmids with hybrid origins in mouse cellsPapillomaviruses use recombination-dependent replication to vegetatively amplify their genomes in differentiated cellsBrd4 is required for e2-mediated transcriptional activation but not genome partitioning of all papillomaviruses.Replication and partitioning of papillomavirus genomes.Evolutionary variation of papillomavirus E2 protein and E2 binding sites.Human papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes.Human Papillomavirus Type 18 cis-Elements Crucial for Segregation and Latency.Genomic instability of the host cell induced by the human papillomavirus replication machineryA papillomavirus E2 phosphorylation mutant exhibits normal transient replication and transcription but is defective in transformation and plasmid retentionCell targeting in anti-cancer gene therapySegregation of viral plasmids depends on tethering to chromosomes and is regulated by phosphorylation.The EBNA1 protein of Epstein-Barr virus functionally interacts with Brd4Current understanding of the role of the Brd4 protein in the papillomavirus lifecycle.The papillomavirus E2 proteinsHitchhiking on host chromatin: how papillomaviruses persist.Transcriptional and replicational activation functions in the bovine papillomavirus type 1 E2 protein are encoded by different structural determinants.Phosphorylation of the Bovine Papillomavirus E2 Protein on Tyrosine Regulates Its Transcription and Replication FunctionsAnalysis of cis-elements that facilitate extrachromosomal persistence of human papillomavirus genomes.Human papillomavirus DNA replication compartments in a transient DNA replication system.
P2860
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P2860
Cis and trans requirements for stable episomal maintenance of the BPV-1 replicator.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
1996年學術文章
@zh
1996年學術文章
@zh-hant
name
Cis and trans requirements for stable episomal maintenance of the BPV-1 replicator.
@en
type
label
Cis and trans requirements for stable episomal maintenance of the BPV-1 replicator.
@en
prefLabel
Cis and trans requirements for stable episomal maintenance of the BPV-1 replicator.
@en
P2093
P2860
P1433
P1476
Cis and trans requirements for stable episomal maintenance of the BPV-1 replicator
@en
P2093
P2860
P356
10.1002/J.1460-2075.1996.TB00328.X
P407
P577
1996-01-01T00:00:00Z