Synthetic epigenetics-towards intelligent control of epigenetic states and cell identity
about
Enabling functional genomics with genome engineeringStrategies for precision modulation of gene expression by epigenome editing: an overviewEpigenetic Editing: On the Verge of Reprogramming Gene Expression at WillLocal chromatin microenvironment determines DNMT activity: from DNA methyltransferase to DNA demethylase or DNA dehydroxymethylaseApplication of CRISPR/Cas9 for biomedical discoveries.TALEored Epigenetics: A DNA-Binding Scaffold for Programmable Epigenome Editing and Analysis.Accelerated genome engineering through multiplexing.Re-expression of Selected Epigenetically Silenced Candidate Tumor Suppressor Genes in Cervical Cancer by TET2-directed Demethylation.Protein Delivery of an Artificial Transcription Factor Restores Widespread Ube3a Expression in an Angelman Syndrome Mouse BrainCRISPR-dCas9 mediated TET1 targeting for selective DNA demethylation at BRCA1 promoter.Targeted epigenetic editing of SPDEF reduces mucus production in lung epithelial cells.Rewriting DNA Methylation Signatures at Will: The Curable Genome Within Reach?Virus-host interplay in hepatitis B virus infection and epigenetic treatment strategies.Epigenome Editing in the Brain.Writing of H3K4Me3 overcomes epigenetic silencing in a sustained but context-dependent manner.Efficient targeted DNA methylation with chimeric dCas9-Dnmt3a-Dnmt3L methyltransferase.Epigenetic drugs: from chemistry via biology to medicine and back.Using CRISPR/Cas in three dimensions: towards synthetic plant genomes, transcriptomes and epigenomes.In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation.A Summary of the Biological Processes, Disease-Associated Changes, and Clinical Applications of DNA Methylation.From Reductionism to Holism: Toward a More Complete View of Development Through Genome Engineering.Engineering of the epigenome: synthetic biology to define functional causality and develop innovative therapies.The past and presence of gene targeting: from chemicals and DNA via proteins to RNA.Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men’s Health, Germination, Sperm Quality, and Fertilization.A modular dCas9-SunTag DNMT3A epigenome editing system overcomes pervasive off-target activity of direct fusion dCas9-DNMT3A constructs
P2860
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P2860
Synthetic epigenetics-towards intelligent control of epigenetic states and cell identity
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
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2015年學術文章
@zh-hant
name
Synthetic epigenetics-towards intelligent control of epigenetic states and cell identity
@en
type
label
Synthetic epigenetics-towards intelligent control of epigenetic states and cell identity
@en
prefLabel
Synthetic epigenetics-towards intelligent control of epigenetic states and cell identity
@en
P2860
P1433
P1476
Synthetic epigenetics-towards intelligent control of epigenetic states and cell identity
@en
P2093
Mirunalini Ravichandran
P2860
P2888
P356
10.1186/S13148-015-0044-X
P577
2015-03-04T00:00:00Z
P5875
P6179
1022329806