ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
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Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cellsOxidized arachidonic and adrenic PEs navigate cells to ferroptosisDioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression."Only a life lived for others is worth living:" Redox Signaling by Oxygenated Phospholipids in Cell Fate Decisions.Modulation of Glutathione Hemostasis by Inhibition of 12/15-Lipoxygenase Prevents ROS-Mediated Cell Death after Hepatic Ischemia and Reperfusion.Iron, Oxidative Damage and Ferroptosis in Rhabdomyosarcoma.Oxidative lipidomics: applications in critical care.HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells.Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure.The in vivo evidence for regulated necrosis.Lipid Peroxidation-Dependent Cell Death Regulated by GPx4 and Ferroptosis.Iron and ferroptosis: A still ill-defined liaison.Ferroptosis: bug or feature?Characterization of ferroptosis in murine models of hemochromatosis.Ethanolamine and Phosphatidylethanolamine: Partners in Health and Disease.Cell Death Pathways: a Novel Therapeutic Approach for Neuroscientists.Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.t-BuOOH induces ferroptosis in human and murine cell lines.ENCoRE: an efficient software for CRISPR screens identifies new players in extrinsic apoptosis.Cell death and immunity in cancer: From danger signals to mimicry of pathogen defense responses.Necroptotic cell death in anti-cancer therapy.The α6β4 integrin promotes resistance to ferroptosis.Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.Heavy metal suicide.Cold stress-induced ferroptosis involves the ASK1-p38 pathway.miR-137 regulates ferroptosis by targeting glutamine transporter SLC1A5 in melanoma.How do we fit ferroptosis in the family of regulated cell death?A role for long-chain acyl-CoA synthetase-4 (ACSL4) in diet-induced phospholipid remodeling and obesity-associated adipocyte dysfunction.Baicalin inhibits PDGF-BB-induced hepatic stellate cell proliferation, apoptosis, invasion, migration and activation via the miR-3595/ACSL4 axis.To eat or not to eat-the metabolic flavor of ferroptosis.Autophagy and Ferroptosis - What's the Connection?Low-density lipoprotein docosahexaenoic acid nanoparticles induce ferroptotic cell death in hepatocellular carcinoma.Heme Oxygenase-1 Mitigates Ferroptosis in Renal Proximal Tubule Cells.Theoretical insights into the mechanism of ferroptosis suppression via inactivation of a lipid peroxide radical by liproxstatin-1.The Aging of Iron Man.Modeling the effects of lipid peroxidation during ferroptosis on membrane properties.Significance and In Vivo Detection of Iron-Laden Microglia in White Matter Multiple Sclerosis Lesions.Determination of the Subcellular Localization and Mechanism of Action of Ferrostatins in Suppressing Ferroptosis.Directing eicosanoid esterification into phospholipids.TFAM is a novel mediator of immunogenic cancer cell death.
P2860
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P2860
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
@en
type
label
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
@en
prefLabel
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
@en
P2093
P2860
P50
P356
P1476
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition.
@en
P2093
Axel Walch
Bettina Proneth
Christina H Scheel
Dietrich Trümbach
Elena Panzilius
Gaowei Mao
Hulya Bayir
Irina Ingold
Joachim Füllekrug
P2860
P2888
P356
10.1038/NCHEMBIO.2239
P577
2016-11-14T00:00:00Z