Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to Circulating Microvesicles
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Generation of Soluble Interleukin-11 and Interleukin-6 Receptors: A Crucial Function for Proteases during InflammationGlycosyl-Phosphatidyl-Inositol (GPI)-Anchors and Metalloproteases: Their Roles in the Regulation of Exosome Composition and NKG2D-Mediated Immune RecognitionProteolytic Origin of the Soluble Human IL-6R In Vivo and a Decisive Role of N-GlycosylationNeutrophil-mediated IL-6 receptor trans-signaling and the risk of chronic obstructive pulmonary disease and asthma.Interleukin-6 Signaling Pathway and Its Role in Kidney Disease: An UpdateIdentification of STOML2 as a putative novel asthma risk gene associated with IL6R.Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling.Role of MicroRNA-103a Targeting ADAM10 in Abdominal Aortic Aneurysm.Circulating Soluble IL-6R but Not ADAM17 Activation Drives Mononuclear Cell Migration in Tissue Inflammation.The Soluble Interleukin 6 Receptor: Advanced Therapeutic Options in Inflammation.Cleavage Site Localization Differentially Controls Interleukin-6 Receptor Proteolysis by ADAM10 and ADAM17.IL6 Signaling in Peripheral Blood T Cells Predicts Clinical Outcome in Breast Cancer.Cellular and Oxidative Mechanisms Associated with Interleukin-6 Signaling in the Vasculature.GRP78 protects a disintegrin and metalloprotease 17 against protein-disulfide isomerase A6 catalyzed inactivation.The Many Facets of Metzincins and Their Endogenous Inhibitors: Perspectives on Ovarian Cancer Progression.A Role for Soluble IL-6 Receptor in Osteoarthritis.ADAM17 is required for EGF-R-induced intestinal tumors via IL-6 trans-signaling.The EGFR-ADAM17 Axis in Chronic Obstructive Pulmonary Disease and Cystic Fibrosis Lung Pathology.Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertensionActivation of the JAK/STAT3 and PI3K/AKT pathways are crucial for IL-6 trans-signaling-mediated pro-inflammatory response in human vascular endothelial cells
P2860
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P2860
Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to Circulating Microvesicles
description
2015 nî lūn-bûn
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
@zh-hk
2015年論文
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2015年論文
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2015年论文
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2015年论文
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2015年论文
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name
Shedding of Endogenous Interle ...... s to Circulating Microvesicles
@en
type
label
Shedding of Endogenous Interle ...... s to Circulating Microvesicles
@en
prefLabel
Shedding of Endogenous Interle ...... s to Circulating Microvesicles
@en
P2093
P2860
P356
P1476
Shedding of Endogenous Interle ...... s to Circulating Microvesicles
@en
P2093
Andre Mauermann
Athena Chalaris
Beate Schacher
Björn Rabe
Christoph Garbers
Dörte Meyer
Gillian Murphy
Jan von der Heyde
Janina Wolf
Jeanette Schwarz
P2860
P304
26059-26071
P356
10.1074/JBC.M115.649509
P407
P577
2015-09-10T00:00:00Z