Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE)
about
Long-range nonanomalous diffusion of quantum dot-labeled aquaporin-1 water channels in the cell plasma membrane.Integrin alpha5beta1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cellsSequential and gamma-secretase-dependent processing of the betacellulin precursor generates a palmitoylated intracellular-domain fragment that inhibits cell growthGeneration of Soluble Interleukin-11 and Interleukin-6 Receptors: A Crucial Function for Proteases during InflammationIL-6 Plays a Crucial Role in HBV InfectionPrevention of colitis-associated cancer: natural compounds that target the IL-6 soluble receptorShedding of collagen XVII ectodomain depends on plasma membrane microenvironmentTrafficking and proteolytic processing of APPADAMs: key components in EGFR signalling and developmentProteolytic Origin of the Soluble Human IL-6R In Vivo and a Decisive Role of N-GlycosylationTraining signaling pathway maps to biochemical data with constrained fuzzy logic: quantitative analysis of liver cell responses to inflammatory stimuliShedding of the p75NTR neurotrophin receptor is modulated by lipid raftsProteomic identification of ADAM12 as a regulator for TGF-β1-induced differentiation of human mesenchymal stem cells to smooth muscle cellsATP-binding cassette transporter G1 negatively regulates thymocyte and peripheral lymphocyte proliferation.Cytoskeletal confinement of CX3CL1 limits its susceptibility to proteolytic cleavage by ADAM10Interleukin-6 Signaling Pathway and Its Role in Kidney Disease: An UpdateOncostatin M receptor β and cysteine/histidine-rich 1 are biomarkers of the response to erythropoietin in hemodialysis patients.ADAM10 is the major sheddase responsible for the release of membrane-associated meprin A.n-3 PUFAs reduce T-helper 17 cell differentiation by decreasing responsiveness to interleukin-6 in isolated mouse splenic CD4⁺ T cells.Leukocyte ADAM17 regulates acute pulmonary inflammation.L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowthCell cholesterol modulates metalloproteinase-dependent shedding of low-density lipoprotein receptor-related protein-1 (LRP-1) and clearance function.Blockade of IL-6 Trans signaling attenuates pulmonary fibrosisADAM10 mediates ectodomain shedding of the betacellulin precursor activated by p-aminophenylmercuric acetate and extracellular calcium influx.ADAM10 regulates transcription factor expression required for plasma cell functionLow cholesterol triggers membrane microdomain-dependent CD44 shedding and suppresses tumor cell migration.Systemic overexpression of TNFα-converting enzyme does not lead to enhanced shedding activity in vivoShedding of collagen XXIII is mediated by furin and depends on the plasma membrane microenvironment.Enhanced IL-6/IL-6R signaling promotes growth and malignant properties in EBV-infected premalignant and cancerous nasopharyngeal epithelial cells.A glycosphingolipid binding domain controls trafficking and activity of the mammalian notch ligand delta-like 1Mesothelin overexpression promotes autocrine IL-6/sIL-6R trans-signaling to stimulate pancreatic cancer cell proliferationIntracellular lipid flux and membrane microdomains as organizing principles in inflammatory cell signalingLigand activation leads to regulated intramembrane proteolysis of fibroblast growth factor receptor 3Plasma membrane microdomains regulate TACE-dependent TNFR1 shedding in human endothelial cells.Shedding of syndecan-1 from human hepatocytes alters very low density lipoprotein clearance.Evidence for functional redundancy between C. elegans ADAM proteins SUP-17/Kuzbanian and ADM-4/TACERadiation Inhibits Interleukin-12 Production via Inhibition of C-Rel through the Interleukin-6/ Signal Transducer and Activator of Transcription 3 Signaling Pathway in Dendritic CellsRole of ADAM17 in the non-cell autonomous effects of oncogene-induced senescence.Use of cyclodextrins to manipulate plasma membrane cholesterol content: evidence, misconceptions and control strategiesSoluble interleukin-6 receptor is elevated during influenza A virus infection and mediates the IL-6 and IL-32 inflammatory cytokine burst.
P2860
Q24294850-7663A25A-E391-4EF5-A86E-EF3999DFCEBEQ24309589-D215F77C-927D-4025-A533-84ED9A55E522Q24633569-C31D6D57-4D4F-45E7-98E2-063E3301155DQ26738992-D9ADE9C1-412E-4FD4-B496-3DABAFF4C19AQ26774879-275826E0-2599-4D1B-8DB7-EF574D754CB1Q27022976-14F716C4-F77C-40BA-B6E5-E8F22D225F60Q28261785-FBD546B5-9BE4-42BF-8289-C4AF594DAECEQ28265871-40D4E32D-15CC-4CFB-98C1-DBEFA52A1597Q28305519-1763A0EE-1A8A-4159-9DEB-2EA210CA9206Q28468416-15596F25-A491-42F6-BB7D-D7D66BDC8DA1Q28477321-6E446E6A-751F-4AD8-B826-D474F4FAA3DBQ28577816-5E7F0666-9583-4F9C-9131-1BF534CB796FQ28727037-B063E7C5-C69A-4BD9-BEBB-F36FEE9CF7CEQ30427703-C30BA29E-B0C2-41CA-AB6F-DF7AD8AC2A2CQ30601949-9890B9D4-D589-428A-9AFA-A77D021444DEQ33586501-624BA9E2-A0E9-4C0F-872E-E9197DB4D18FQ33625452-0D732A4B-A2C8-4B1A-885B-1BFE21E45F6CQ33676656-3D54A626-2C41-4EDA-839F-DC1EEFCEE20BQ33888245-513D3505-1E41-43D7-8333-BA8C3A3B9BDEQ33908463-26123CDA-DCAC-49F8-A069-25737508662EQ34097273-76B60A6D-CC1B-471B-B4CE-E7D176A03CD1Q34180389-E911C570-46E4-4146-82C4-DB77415E7D30Q34218604-CC208A35-8943-40A8-B42A-AE5CAC6788C8Q34362287-05D7E2F9-8B3A-430F-A49F-2DAAB763E875Q34374623-52B4AB95-23EE-4BB9-9D1F-F81C17C30ABFQ34503158-2E377D1E-54F1-4B7A-BAD7-D8D6A7784357Q34559443-5872DF2D-C4D3-4047-B45C-377DD243CDA7Q34649929-6DFB6B63-532C-42B4-B3F3-EE3E19D82DE8Q34712473-5D17B788-B28E-4EAD-97C4-EF0F77FCAD1CQ34999166-BDC671C9-9D02-4516-B796-55361C0FB8CAQ35083542-2C4B282A-173C-4C8E-AAD4-295D7AA7BF7BQ35150394-9A7119CC-393D-45C3-B0CC-9A7CE08FECFBQ35340703-B2D766A8-00BB-4789-8FDD-7BC2C34AC8E1Q35456998-E5787CA2-3ADC-4353-9289-097060BAE864Q35631767-10AAB4C0-F5B2-4340-8FD1-983FEC986E32Q35651962-CB559B61-77DE-48EE-939D-EC20DE3B4B7DQ35888942-124B7DD6-D6EA-4FC3-8E04-6554A7A47DC1Q35939308-5226FB8A-20D6-45F9-9013-47950D7938BFQ35940287-39A7FED9-850F-4A51-AB7D-4F2921A46208Q36085075-8B3F6A62-945B-477B-8BBA-82BC9EBFCA49
P2860
Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE)
description
2003 nî lūn-bûn
@nan
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Cellular cholesterol depletion ...... or by ADAM10 and ADAM17 (TACE)
@ast
Cellular cholesterol depletion ...... or by ADAM10 and ADAM17 (TACE)
@en
Cellular cholesterol depletion ...... or by ADAM10 and ADAM17 (TACE)
@en-gb
Cellular cholesterol depletion ...... or by ADAM10 and ADAM17 (TACE)
@nl
type
label
Cellular cholesterol depletion ...... or by ADAM10 and ADAM17 (TACE)
@ast
Cellular cholesterol depletion ...... or by ADAM10 and ADAM17 (TACE)
@en
Cellular cholesterol depletion ...... or by ADAM10 and ADAM17 (TACE)
@en-gb
Cellular cholesterol depletion ...... or by ADAM10 and ADAM17 (TACE)
@nl
prefLabel
Cellular cholesterol depletion ...... or by ADAM10 and ADAM17 (TACE)
@ast
Cellular cholesterol depletion ...... or by ADAM10 and ADAM17 (TACE)
@en
Cellular cholesterol depletion ...... or by ADAM10 and ADAM17 (TACE)
@en-gb
Cellular cholesterol depletion ...... or by ADAM10 and ADAM17 (TACE)
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
Cellular cholesterol depletion ...... or by ADAM10 and ADAM17 (TACE)
@en
P2093
Björn Schuster
Christian Hundhausen
Dieter Hartmann
Ingo Bussmeyer
Karl-Josef Kallen
Stefan Schütze
Thorsten Sadowski
Vance Matthews
P2860
P304
P3181
P356
10.1074/JBC.M210584200
P407
P577
2003-10-03T00:00:00Z