Presenilin 1 Maintains Lysosomal Ca(2+) Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification.
about
"TRP inflammation" relationship in cardiovascular systemTwo-Pore Channels and Parkinson's Disease: Where's the Link?Proteases Revisited: Roles and Therapeutic Implications in Fibrosis.Mitofusin-2 knockdown increases ER-mitochondria contact and decreases amyloid β-peptide productionLysosome acidification by photoactivated nanoparticles restores autophagy under lipotoxicity.Autophagy flux in CA1 neurons of Alzheimer hippocampus: Increased induction overburdens failing lysosomes to propel neuritic dystrophy.Lysosomal adaptation: How cells respond to lysosomotropic compounds.Acidic Ca2+ stores in neurodegeneration.The Autophagy-Lysosomal Pathway in Neurodegeneration: A TFEB PerspectiveEndoplasmic reticulum and lysosomal Ca²⁺ stores are remodelled in GBA1-linked Parkinson disease patient fibroblasts.Autophagy-ERK1/2-Involved Disinhibition of Hippocampal Neurons Contributes to the Pre-Synaptic Toxicity Induced by Aβ42 Exposure.PIKfyve Regulates Vacuole Maturation and Nutrient Recovery following Engulfment.Disorders of lysosomal acidification-The emerging role of v-ATPase in aging and neurodegenerative disease.Calcium's role as nuanced modulator of cellular physiology in the brain.The Role of Presenilin in Protein Trafficking and Degradation-Implications for Metal Homeostasis.Emerging pathways driving early synaptic pathology in Alzheimer's disease.Anesthetic neurotoxicity: Apoptosis and autophagic cell death mediated by calcium dysregulation.Prelysosomal Compartments in the Unconventional Secretion of Amyloidogenic Seeds.The role of Ca2+ signaling in Parkinson's disease.Defective Transcytosis of APP and Lipoproteins in Human iPSC-Derived Neurons with Familial Alzheimer's Disease Mutations.Amyloid precursor protein and endosomal-lysosomal dysfunction in Alzheimer's disease: inseparable partners in a multifactorial disease.Autophagy in neurodegenerative diseases: pathogenesis and therapy.Endo-lysosomal TRP mucolipin-1 channels trigger global ER Ca2+ release and Ca2+ influx.Targeting neuronal MAPK14/p38α activity to modulate autophagy in the Alzheimer disease brain.Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer's Disease-Associated Presenilin 1 Mutation.Connecting Ca2+ and lysosomes to Parkinson disease.Deviant lysosomal Ca2+ signalling in neurodegeneration. An introduction.Lysosomal Ca2+ Signaling Regulates High Glucose-Mediated Interleukin-1β Secretion via Transcription Factor EB in Human Monocytic Cells.General Anesthetics Regulate Autophagy via Modulating the Inositol 1,4,5-Trisphosphate Receptor: Implications for Dual Effects of Cytoprotection and Cytotoxicity.Curcumin Exerts Effects on the Pathophysiology of Alzheimer's Disease by Regulating PI(3,5)P2 and Transient Receptor Potential Mucolipin-1 Expression.Structure of mammalian endolysosomal TRPML1 channel in nanodiscs.Lysosomal Calcium in Neurodegeneration.The lysosomal Ca2+ release channel TRPML1 regulates lysosome size by activating calmodulin.Organellar Omics-A Reviving Strategy to Untangle the Biomolecular Complexity of the Cell.MicroRNA Profiling in Aging Brain of PSEN1/PSEN2 Double Knockout Mice.Dysfunction of autophagy and endosomal-lysosomal pathways: Roles in pathogenesis of Down syndrome and Alzheimer's Disease.The curious case of vacuolar ATPase: regulation of signaling pathways.Cathepsin D Polymorphism C224T in Childhood-Onset Neurodegenerative Disorders: No Impact for Childhood Dementia.[Autophagy and brain: the case of neurodegenerative diseases].Neuronal lysosomes.
P2860
Q26781720-E618A164-BD29-408F-B82F-12562AE359C0Q33703425-1D7CE8D4-C15F-49A1-91D2-1D2DAE6B3B96Q33795055-72B94150-20EE-4DCF-B163-E29EDC983766Q34527610-8A7D5CDE-87DC-461A-B602-1E3D7BD541B8Q34532901-11EE0AEB-3A2C-4DEF-B80D-4F4E3706437AQ36182739-F6A42CCC-5D7A-4624-AB7F-27F57F049053Q36310581-A3F03D44-584A-4C4B-BB47-C6404B847571Q36395510-99F68331-E991-4603-A14F-BEC5C9F46B5BQ37055497-7D37C96D-ABFF-496E-867F-456D3F82B4D8Q38389995-83839A35-4AEC-42B0-AE92-802186C56B74Q38683916-13E1D119-2A30-4F2D-BB8D-5DA54CACD25FQ38746550-E87F69EC-70ED-4322-A7DF-812EFFA2C5F2Q38838536-C1C41DD6-1BE1-4EE1-8E25-EF0D330595B1Q38935052-FDEB9452-F352-4D18-BDE8-E28ACADC66EFQ38936434-77CF997B-E16E-4BFC-8AFB-E3A73953DB89Q38962140-8E4216B5-CF2E-4A14-956E-AFF091A1ACDBQ39011212-F4BF5A66-209B-49E3-B791-BACF527F524DQ39104462-FF91F751-DB16-46D9-8F16-FC0F4731F843Q39281423-A6A80C0F-A495-47F6-BA9E-A237CBC6D7D7Q39298977-E5FA9C66-1F8E-4C1F-8AD8-DE12FDBD4E26Q39405747-5A444B3D-21A1-47FA-B117-59E3B81EA527Q39432638-9A9642C2-B74F-4C7C-9005-56298A733283Q39438967-4721F731-7884-4F02-9CC5-764B673F1A9CQ39547451-D4889929-865B-413B-B13B-E8F6C9CAB31AQ41673213-9AAA4F39-7944-4320-9B1E-170C8B169E0DQ42255446-C615CAFE-5F1D-497B-B58A-C3939DA0F589Q42257818-3AC81189-AE6A-47A7-8971-570F82701418Q42362535-E96E1ECF-77B3-4FBD-8BC0-79683EE8E0C7Q42366448-0593B87D-F404-4711-9C74-764A05D54944Q42778269-B0B5DAB7-3BAF-443D-A2E5-7C9BF8A6B8E8Q47035965-F3BD3578-37AA-4935-A19F-0B5FC103C56DQ47124126-E1DDC344-1ED2-4024-9B2C-DAFE8195A321Q47224732-1AF26F59-679F-4518-AEDB-BEEB0A1B26C9Q47975495-E8C3A50F-CD3D-4645-8F83-4D33151B6E3BQ48115198-C64D00B1-DB56-4FB8-A2C2-A6D92A509BCFQ49497621-8EDE249B-2D3B-4482-B520-E72BD04A89B0Q49963014-D8FDA0C1-8A6B-4BAC-B8FD-AD6899F1C0DCQ50021884-AF76C3D3-2417-403B-AA1C-45EF0FCB38BFQ51831274-855BDED1-D59E-4B4D-B643-5CD5215A2D57Q52601345-3D2AADF4-2730-42BC-A544-9234F50143A3
P2860
Presenilin 1 Maintains Lysosomal Ca(2+) Homeostasis via TRPML1 by Regulating vATPase-Mediated Lysosome Acidification.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Presenilin 1 Maintains Lysosom ...... diated Lysosome Acidification.
@en
type
label
Presenilin 1 Maintains Lysosom ...... diated Lysosome Acidification.
@en
prefLabel
Presenilin 1 Maintains Lysosom ...... diated Lysosome Acidification.
@en
P2093
P2860
P1433
P1476
Presenilin 1 Maintains Lysosom ...... ediated Lysosome Acidification
@en
P2093
Asok Kumar
Claire H Mitchell
Devin M Wolfe
Emyr Lloyd-Evans
Erin E Coffey
Luke J Haslett
Mary Kate McBrayer
Panaiyur Mohan
Pearl P Y Lie
Ralph A Nixon
P2860
P304
P356
10.1016/J.CELREP.2015.07.050
P50
P577
2015-08-20T00:00:00Z