Single-Cell Transcriptomics of the Human Endocrine Pancreas. - Wikidata - wikimedia - TriplyDB

Single-Cell Transcriptomics of the Human Endocrine Pancreas.

Single-Cell Transcriptomics of the Human Endocrine Pancreas.

http://www.wikidata.org/entity/Q38846538

about

Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes.Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.A Single-Cell Transcriptome Atlas of the Human Pancreas.PAX6 maintains β cell identity by repressing genes of alternative islet cell types.MiRNAs in β-Cell Development, Identity, and Disease.Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.Metabolic Stress and Compromised Identity of Pancreatic Beta Cells.Evidence for Loss in Identity, De-Differentiation, and Trans-Differentiation of Islet β-Cells in Type 2 Diabetes.Single-cell transcriptomics of East-Asian pancreatic islets cells.Single-Cell RNA-Sequencing: Assessment of Differential Expression Analysis Methods.Pancreatic Islet Protein Complexes and Their Dysregulation in Type 2 Diabetes Pseudotemporal Ordering of Single Cells Reveals Metabolic Control of Postnatal β Cell Proliferation.Immunohistochemical assessment of glucagon-like peptide 1 receptor (GLP-1R) expression in the pancreas of patients with type 2 diabetes.Is a β cell a β cell?Genomics of Islet (Dys)function and Type 2 Diabetes.All mixed up: defining roles for β-cell subtypes in mature islets.Beta cell heterogeneity: an evolving concept.Human Retrotransposon Insertion Polymorphisms Are Associated with Health and Disease via Gene Regulatory Phenotypes Systematic single-cell analysis provides new insights into heterogeneity and plasticity of the pancreas.Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis.Epigenetics in formation, function, and failure of the endocrine pancreas.Interrogating islets in health and disease with single-cell technologies Different developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth.Alpha TC1 and Beta-TC-6 genomic profiling uncovers both shared and distinct transcriptional regulatory features with their primary islet counterparts.Single-Cell Gene Expression Analysis of a Human ESC Model of Pancreatic Endocrine Development Reveals Different Paths to β-Cell Differentiation.Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns.Cross-Tissue Identification of Somatic Stem and Progenitor Cells Using a Single-Cell RNA-Sequencing Derived Gene Signature.Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.Unravelling biology and shifting paradigms in cancer with single-cell sequencing.The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates.β-Cells are not uniform after all-Novel insights into molecular heterogeneity of insulin-secreting cells.Cellular and molecular mechanisms coordinating pancreas development.Bottom-up proteomics analysis of the secretome of murine islets of Langerhans in elevated glucose levels.Pancreatic β-Cells Express the Fetal Islet Hormone Gastrin in Rodent and Human Diabetes.Characterizing the replicability of cell types defined by single cell RNA-sequencing data using MetaNeighbor.Cell type discovery using single-cell transcriptomics: implications for ontological representation.Single-cell analyses of human islet cells reveal de-differentiation signatures.Heterogeneity and cell fate flux in single human pancreatic islet cells.The role of beta cell heterogeneity in islet function and insulin release.Cellular network modeling and single cell gene expression analysis reveals novel hepatic stellate cell phenotypes controlling liver regeneration dynamics

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Single-Cell Transcriptomics of the Human Endocrine Pancreas.

http://www.wikidata.org/entity/Q38846538

description

2016 nî lūn-bûn

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2016年の論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年論文

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2016年论文

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2016年论文

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2016年论文

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name

Single-Cell Transcriptomics of the Human Endocrine Pancreas.

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type

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Single-Cell Transcriptomics of the Human Endocrine Pancreas.

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Single-Cell Transcriptomics of the Human Endocrine Pancreas.

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Single-Cell Transcriptomics of the Human Endocrine Pancreas

@en

P2093

Ali Naji

http://www.w3.org/2001/XMLSchema#string

Chengyang Liu

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Dana Avrahami

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Jonathan Schug

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Klaus H Kaestner

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Maria L Golson

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P2860

Regulation of PKD by the MAPK p38delta in insulin secretion and glucose homeostasis

The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

Genomic analysis at the single-cell level

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

Pancreatic islet plasticity: interspecies comparison of islet architecture and composition

Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2

Single-cell transcriptomics reveals bimodality in expression and splicing in immune cells

Epigenomic plasticity enables human pancreatic α to β cell reprogramming.

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Aizkuņģa dziedzeris

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