Hepatitis C virus genetic variability and the presence of NS5B resistance-associated mutations as natural polymorphisms in selected genotypes could affect the response to NS5B inhibitors.
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Mouse Systems to Model Hepatitis C Virus Treatment and Associated ResistanceState of the Art, Unresolved Issues, and Future Research Directions in the Fight against Hepatitis C Virus: Perspectives for Screening, Diagnostics of Resistances, and ImmunizationMultiple Introduction and Naturally Occuring Drug Resistance of HCV among HIV-Infected Intravenous Drug Users in Yunnan: An Origin of China's HIV/HCV EpidemicsGenetic Barrier to Direct Acting Antivirals in HCV Sequences Deposited in the European DatabankNaturally occurring drug resistance associated variants to hepatitis C virus direct-acting antiviral agents in treatment-naive HCV genotype 1b-infected patients in China.Identification of HCV Resistant Variants against Direct Acting Antivirals in Plasma and Liver of Treatment Naïve PatientsUpdate on different aspects of HCV variability: focus on NS5B polymerase.Comprehensive Screening for Naturally Occurring Hepatitis C Virus Resistance to Direct-Acting Antivirals in the NS3, NS5A, and NS5B Genes in Worldwide Isolates of Viral Genotypes 1 to 6Detection of Natural Resistance-Associated Substitutions by Ion Semiconductor Technology in HCV1b Positive, Direct-Acting Antiviral Agents-Naïve PatientsOmbitasvir (ABT-267), a novel NS5A inhibitor for the treatment of hepatitis C.Identification of potential inhibitors for HCV NS3 genotype 4a by combining protein-ligand interaction fingerprint, 3D pharmacophore, docking, and dynamic simulation.Prevention and management of treatment failure to new oral hepatitis C drugs.Hepatitis C virus resistance to the new direct-acting antivirals.Hepatitis C virus genotype 3A in a population of injecting drug users in Montenegro: Bayesian and evolutionary analysis.Resistance Mechanisms in Hepatitis C Virus: implications for Direct-Acting Antiviral Use.NMR reveals the intrinsically disordered domain 2 of NS5A protein as an allosteric regulator of the hepatitis C virus RNA polymerase NS5B.Molecular characterization and epidemic history of hepatitis C virus using core sequences of isolates from Central Province, Saudi Arabia.Naturally Occurring Resistance-Associated Variants to Hepatitis C Virus Direct-Acting Antiviral Agents in Treatment-Naive HCV Genotype 6a-Infected Patients.Characterization of NS5A and NS5B Resistance-Associated Substitutions from Genotype 1 Hepatitis C Virus Infected Patients in a Portuguese Cohort.Epidemic history of hepatitis C virus genotypes and subtypes in PortugalBaseline dasabuvir resistance in Hepatitis C virus from the genotypes 1, 2 and 3 and modeling of the NS5B-dasabuvir complex by the approach
P2860
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P2860
Hepatitis C virus genetic variability and the presence of NS5B resistance-associated mutations as natural polymorphisms in selected genotypes could affect the response to NS5B inhibitors.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
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2014年论文
@zh-cn
name
Hepatitis C virus genetic vari ...... e response to NS5B inhibitors.
@en
type
label
Hepatitis C virus genetic vari ...... e response to NS5B inhibitors.
@en
prefLabel
Hepatitis C virus genetic vari ...... e response to NS5B inhibitors.
@en
P2093
P2860
P356
P1476
Hepatitis C virus genetic vari ...... e response to NS5B inhibitors.
@en
P2093
C Mirabelli
F Ceccherini-Silberstein
V C Di Maio
P2860
P304
P356
10.1128/AAC.02386-13
P407
P577
2014-03-03T00:00:00Z