Discriminating self from non-self in nucleic acid sensing.
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The murine cytomegalovirus M35 protein antagonizes type I IFN induction downstream of pattern recognition receptors by targeting NF-κB mediated transcriptionDecreased Expression of TMEM173 Predicts Poor Prognosis in Patients with Hepatocellular CarcinomaHarnessing Nanoparticles for Immunomodulation and VaccinesAmplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression.The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity.New insights into the immunopathogenesis of systemic lupus erythematosus.Nucleic acid-sensing TLRs: trafficking and regulation.Crosstalk between Cytoplasmic RIG-I and STING Sensing Pathways.Avian Interferons and Their Antiviral Effectors.B-cell tolerance and autoimmunity.Coordinated Role of Toll-Like Receptor-3 and Retinoic Acid-Inducible Gene-I in the Innate Response of Bovine Endometrial Cells to Virus.The RNA helicase DDX46 inhibits innate immunity by entrapping m6A-demethylated antiviral transcripts in the nucleus.cGAMP Quantification in Virus-Infected Human Monocyte-Derived Cells by HPLC-Coupled Tandem Mass Spectrometry.cGAS is activated by DNA in a length-dependent manner.A parapoxviral virion protein inhibits NF-κB signaling early in infection.RIG-I Activation Protects and Rescues from Lethal Influenza Virus Infection and Bacterial Superinfection.B. abortus RNA is the component involved in the down-modulation of MHC-I expression on human monocytes via TLR8 and the EGFR pathway.Human noncoding RNA 886 (nc886) adopts two structurally distinct conformers that are functionally opposing regulators of PKR.Uniquely conserved immunosuppressive viral exoribonucleasesDiscovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay.Long-lasting antiviral innate immune priming in the Lophotrochozoan Pacific oyster, Crassostrea gigas.RNA editing by ADAR1 regulates innate and antiviral immune functions in primary macrophages.Evaluation and control of miRNA-like off-target repression for RNA interference.The Significance of Type-I Interferons in the Pathogenesis and Therapy of Human Immunodeficiency Virus 1 Infection.Viral unmasking of cellular 5S rRNA pseudogene transcripts induces RIG-I-mediated immunity.Type I interferon-mediated autoinflammation due to DNase II deficiency.The catalytic mechanism of cyclic GMP-AMP synthase (cGAS) and implications for innate immunity and inhibition.Innate immune control of alphavirus infection.The RIG-I-like receptor LGP2 inhibits Dicer-dependent processing of long double-stranded RNA and blocks RNA interference in mammalian cells.Self-RNA sentinels signal viral invasion.Interferon-Stimulated Genes as Enhancers of Antiviral Innate Immune Signaling.The Scaffolding Protein IQGAP1 Interacts with NLRC3 and Inhibits Type I IFN Production.Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors.Negative regulation of B cell responses and self-tolerance to RNA-related lupus self-antigen.PARP1 depletion induces RIG-I-dependent signaling in human cancer cells.CRISPR RNAs trigger innate immune responses in human cells.Understanding the causes and consequences of measles virus persistence.Cyclin-dependent kinase activity is required for type I interferon production.STING agonists enable antiviral cross-talk between human cells and confer protection against genital herpes in mice.Nuclear-resident RIG-I senses viral replication inducing antiviral immunity
P2860
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P2860
Discriminating self from non-self in nucleic acid sensing.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Discriminating self from non-self in nucleic acid sensing.
@en
type
label
Discriminating self from non-self in nucleic acid sensing.
@en
prefLabel
Discriminating self from non-self in nucleic acid sensing.
@en
P2860
P356
P1476
Discriminating self from non-self in nucleic acid sensing.
@en
P2860
P304
P356
10.1038/NRI.2016.78
P577
2016-07-25T00:00:00Z