RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway.
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An outline of necrosome triggersBacterial Exotoxins and the InflammasomeMolecular mechanisms regulating NLRP3 inflammasome activationReactive oxygen species and mitochondria: A nexus of cellular homeostasisThe two faces of receptor interacting protein kinase-1Mechanisms of inflammasome activation: recent advances and novel insightsNatural Compounds as Regulators of NLRP3 Inflammasome-Mediated IL-1β ProductionRecent Advances of the NLRP3 Inflammasome in Central Nervous System DisordersUbiquitin in Influenza Virus Entry and Innate ImmunityCellular and molecular regulation of innate inflammatory responsesInitiation and perpetuation of NLRP3 inflammasome activation and assemblyInflammasome control of viral infectionThe intersection of cell death and inflammasome activationRIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKLPINK1/Parkin-Dependent Mitochondrial Surveillance: From Pleiotropy to Parkinson's Disease.Inhibition of Drp1 hyper-activation is protective in animal models of experimental multiple sclerosis.Programmed necrosis in inflammation: Toward identification of the effector molecules.Deletion of FADD in macrophages and granulocytes results in RIP3- and MyD88-dependent systemic inflammationToxin-induced necroptosis is a major mechanism of Staphylococcus aureus lung damage.Regulation of inflammasome activation.Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3Pore-Forming Toxins Induce Macrophage Necroptosis during Acute Bacterial Pneumonia.Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome SignalingRIPK3 Is Largely Dispensable for RIG-I-Like Receptor- and Type I Interferon-Driven Transcriptional Responses to Influenza A Virus in Murine Fibroblasts.Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.Defective mitochondrial fission augments NLRP3 inflammasome activationRIPK3 interacts with MAVS to regulate type I IFN-mediated immunity to Influenza A virus infectionThe Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages.NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions.Peroxisome Proliferator-activated Receptor-γ Coactivator 1-α (PGC1α) Protects against Experimental Murine ColitisIntracellular detection of viral nucleic acids.ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways.Emerging Roles for RIPK1 and RIPK3 in Pathogen-Induced Cell Death and Host Immunity.Paclitaxel nanoparticle awakens immune system to fight against cancer.Therapy-induced microenvironmental changes in cancer.RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus.Necroptosis-independent signaling by the RIP kinases in inflammation.K(+) regulates Ca(2+) to drive inflammasome signaling: dynamic visualization of ion flux in live cells.Necroptosis: A Novel Cell Death Modality and Its Potential Relevance for Critical Care Medicine.RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation.
P2860
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P2860
RNA viruses promote activation of the NLRP3 inflammasome through a RIP1-RIP3-DRP1 signaling pathway.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
RNA viruses promote activation ...... 1-RIP3-DRP1 signaling pathway.
@en
type
label
RNA viruses promote activation ...... 1-RIP3-DRP1 signaling pathway.
@en
prefLabel
RNA viruses promote activation ...... 1-RIP3-DRP1 signaling pathway.
@en
P2093
P2860
P356
P1433
P1476
RNA viruses promote activation ...... P1-RIP3-DRP1 signaling pathway
@en
P2093
Jiahuai Han
Rongbin Zhou
Xiaqiong Wang
Yiqing Yan
Zhigang Tian
P2860
P304
P356
10.1038/NI.3015
P407
P50
P577
2014-10-19T00:00:00Z