EGFR blockade enriches for lung cancer stem-like cells through Notch3-dependent signaling. - Wikidata - wikimedia - TriplyDB

EGFR blockade enriches for lung cancer stem-like cells through Notch3-dependent signaling.

EGFR blockade enriches for lung cancer stem-like cells through Notch3-dependent signaling.

http://www.wikidata.org/entity/Q38965827

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The role of epithelial to mesenchymal transition in resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer Targeting Notch to overcome radiation resistance Advances in Lung Stem Cells and Lung Cancer Stem Cells Deciphering Crosstalk Circuits in Non-small Cell Lung Cancers with an Increasing Interval Length of Low Dose CT Screening Epidermal growth factor receptor and notch signaling in non-small-cell lung cancer Triptolide suppresses the in vitro and in vivo growth of lung cancer cells by targeting hyaluronan-CD44/RHAMM signaling.Notch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application.Randomized Adjuvant Chemotherapy of EGFR-Mutated Non-Small Cell Lung Cancer Patients with or without Icotinib Consolidation Therapy.Tyr1068-phosphorylated epidermal growth factor receptor (EGFR) predicts cancer stem cell targeting by erlotinib in preclinical models of wild-type EGFR lung cancer Aberrant activation of Notch signaling in extrahepatic cholangiocarcinoma: clinicopathological features and therapeutic potential for cancer stem cell-like properties Monitoring cancer stem cells: insights into clinical oncology.Musashi-2 (MSI2) supports TGF-β signaling and inhibits claudins to promote non-small cell lung cancer (NSCLC) metastasis.FGFR1 promotes the stem cell-like phenotype of FGFR1-amplified non-small cell lung cancer cells through the Hedgehog pathway.Notch4+ cancer stem-like cells promote the metastatic and invasive ability of melanoma.Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression.Short-term EGFR blockade enhances immune-mediated cytotoxicity of EGFR mutant lung cancer cells: rationale for combination therapies.A feed-forward loop between lncARSR and YAP activity promotes expansion of renal tumour-initiating cells.Carbon ion irradiation withstands cancer stem cells' migration/invasion process in Head and Neck Squamous Cell Carcinoma (HNSCC).Epigenetic therapy potential of suberoylanilide hydroxamic acid on invasive human non-small cell lung cancer cells Cancer stem cells and tumor-associated macrophages: a roadmap for multitargeting strategies.Antagonism of EGFR and Notch limits resistance to EGFR inhibitors and radiation by decreasing tumor-initiating cell frequency.Notch3 signaling-mediated melanoma-endothelial crosstalk regulates melanoma stem-like cell homeostasis and niche morphogenesis.Inhibition of the cancer stem cells-like properties by arsenic trioxide, involved in the attenuation of endogenous transforming growth factor beta signal.Concise Review: Emerging Drugs Targeting Epithelial Cancer Stem-Like Cells.Activation of signal transducer and activator of transcription 3 (STAT3) signaling in EGFR mutant non-small-cell lung cancer (NSCLC)Inhibition of Hes1 enhances lapatinib sensitivity in gastric cancer sphere-forming cells.Sulforaphane reverses gefitinib tolerance in human lung cancer cells via modulation of sonic hedgehog signaling.LncRNAs and their role in cancer stem cells.Combined Erlotinib and PF-03084014 treatment contributes to synthetic lethality in head and neck squamous cell carcinoma.Prospects for new lung cancer treatments that target EMT signaling.Evaluation of role of Notch3 signaling pathway in human lung cancer cells.NOTCH3 inactivation increases triple negative breast cancer sensitivity to gefitinib by promoting EGFR tyrosine dephosphorylation and its intracellular arrest.NOTCH3 binds activated EGFR EGFR phosphorylates NOTCH3 NOTCH3 Activation and Transmission of Signal to the Nucleus Notch3-dependent β-catenin signaling mediates EGFR TKI drug persistence in EGFR mutant NSCLC

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EGFR blockade enriches for lung cancer stem-like cells through Notch3-dependent signaling.

http://www.wikidata.org/entity/Q38965827

description

2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

@zh-mo

2014年論文

@zh-tw

2014年论文

@wuu

2014年论文

@zh

2014年论文

@zh-cn

name

EGFR blockade enriches for lun ...... gh Notch3-dependent signaling.

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type

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EGFR blockade enriches for lun ...... gh Notch3-dependent signaling.

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EGFR blockade enriches for lun ...... gh Notch3-dependent signaling.

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0008-5472.CAN-13-3724

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Cancer Research

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EGFR blockade enriches for lun ...... gh Notch3-dependent signaling.

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P2093

David P Carbone

http://www.w3.org/2001/XMLSchema#string

Joseph M Amann

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Mohammad A Rahman

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Rajeswara Rao Arasada

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Stacey S Huppert

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P2860

Dominant enhancers of Egfr in Drosophila melanogaster: genetic links between the Notch and Egfr signaling pathways

Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling

Notch and EGFR pathway interaction regulates neural stem cell number and self-renewal

Combined BRAF and MEK inhibition in melanoma with BRAF V600 mutations

IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland

Alterations of the Notch pathway in lung cancer.

Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma

Notch signaling: cell fate control and signal integration in development

PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR

Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR

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5572-5584

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10.1158/0008-5472.CAN-13-3724

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19

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74

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2014-08-14T00:00:00Z

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4263272

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